Search Results - "Nguan, Christopher Y"

Correlation of surface-enhanced Raman spectroscopic fingerprints of kidney transplant recipient urine with kidney function parameters by Huang, Zhongli, Feng, Shijian, Guan, Qiunong, Lin, Tao, Zhao, Jianhua, Nguan, Christopher Y. C., Zeng, Haishan, Harriman, David, Li, Hong, Du, Caigan

“…Routine monitoring of kidney transplant function is required for the standard care in post-transplantation management, including frequent measurements of serum…”
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Relationship of clusterin with renal inflammation and fibrosis after the recovery phase of ischemia-reperfusion injury by Guo, Jia, Guan, Qiunong, Liu, Xiuheng, Wang, Hao, Gleave, Martin E, Nguan, Christopher Y C, Du, Caigan

“…Long-term outcomes after acute kidney injury (AKI) include incremental loss of function and progression towards chronic kidney disease (CKD); however, the…”
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Promotion of cell proliferation by clusterin in the renal tissue repair phase after ischemia-reperfusion injury by Nguan, Christopher Y C, Guan, Qiunong, Gleave, Martin E, Du, Caigan

“…Renal repair begins soon after the kidney suffers ischemia-reperfusion injury (IRI); however, its molecular pathways are not fully understood. Clusterin (Clu)…”
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Hyperbranched polyglycerol as a colloid in cold organ preservation solutions by Gao, Sihai, Guan, Qiunong, Chafeeva, Irina, Brooks, Donald E, Nguan, Christopher Y C, Kizhakkedathu, Jayachandran N, Du, Caigan

“…Hydroxyethyl starch (HES) is a common colloid in organ preservation solutions, such as in University of Wisconsin (UW) solution, for preventing graft…”
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Halofuginone Synergistically Enhances Anti-Proliferation of Rapamycin in T Cells and Reduces Cytotoxicity of Cyclosporine in Cultured Renal Tubular Epithelial Cells by Chu, Tony L H, Guan, Qiunong, Nguan, Christopher Y C, Du, Caigan

“…Both rapamycin (RAPA) and cyclosporin A (CsA) are commonly used for immunosuppression, however their adverse side effects limit their application. Thus, it is…”
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Clusterin Deficiency Predisposes C57BL/6j Mice to Cationic Bovine Serum Albumin-Induced Glomerular Inflammation by Sun, Pengcheng, Feng, Shijian, Guan, Qiunong, Adomat, Hans, Barbour, Sean, Gleave, Martin E, Nguan, Christopher Y C, Xu, Wanhai, Du, Caigan

“…Membranous nephropathy (MN) is a specific entity of glomerulonephritis, and its glomerular inflammation is characterized by the deposition of immune complexes…”
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Expression of Transforming Growth Factor-β1 Limits Renal Ischemia-Reperfusion Injury by QIUNONG GUAN, NGUAN, Christopher Y. C, CAIGAN DU

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Transcriptome-Based Analysis of Molecular Pathways for Clusterin Functions in Kidney Cells by Dairi, Ghida, Guan, Qiunong, Roshan-Moniri, Mani, Collins, Colin C., Ong, Christopher J., Gleave, Martin E., Nguan, Christopher Y.C., Du, Caigan

“…Clusterin (CLU) is a chaperone‐like protein and plays a protective role against renal ischemia‐reperfusion injury (IRI); however, the molecular pathways for…”
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Loss of clusterin expression worsens renal ischemia-reperfusion injury by Zhou, Wenjun, Guan, Qiunong, Kwan, Chris C H, Chen, Huifang, Gleave, Martin E, Nguan, Christopher Y C, Du, Caigan

“…Prevention of ischemia-reperfusion injury (IRI) is a challenge in clinical care of the patients with kidney transplants or acute kidney injury, and…”
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Decrease in donor heart injury by recombinant clusterin protein in cold preservation with University of Wisconsin solution by Guan, Qiunong, MPhil, Li, Shuyuan, MD, PhD, Yip, Gordon, BS, Gleave, Martin E., MD, PhD, Nguan, Christopher Y.C., MD, Du, Caigan, PhD

“…Background Donor organ injury during cold preservation before transplantation negatively impacts graft survival. Clusterin (CLU) is a chaperonic protein, and…”
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Reduction of cold ischemia–reperfusion injury by graft-expressing clusterin in heart transplantation by Li, Shuyuan, MD, Guan, Qiunong, MPhil, Chen, Zhishui, MD, PhD, Gleave, Martin E., MD, PhD, Nguan, Christopher Y.C., MD, Du, Caigan, PhD

“…Background Cold ischemia–reperfusion injury (IRI) is a major factor for early graft dysfunction and is associated with rejection episodes in heart…”
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The COSMIC Bubble Helmet: A Non-Invasive Positive Pressure Ventilation System for COVID-19 by Gusti, Vionarica, Wu, Wan Jun, Grover, Arpan, Chiu, Sabian, Su, Kai-Wen, Ma, Erica, Chow, Chanelle K., Sit, Ella, Lim, Jun, Pandhari, Abhijit, Park, Mattias, Lee, Ryan, Shahril, Faisal, Lim, Shawn T., Nguan, Christopher Y., Driedger, Dan, Sinha, Avinash K., Scrooby, Ivan G., Mclean, Neilson J., Lee, Michael W., Yan, Tyler D., COSMIC Team, The

“…Goal: COSMIC Medical, a Vancouver-based open-source volunteer initiative, has designed an accessible, affordable, and aerosol-confining non-invasive…”
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Treatment of renal transplant complications with a mesh hood fascial closure technique by Nguan, Christopher Y.C., M.D., F.R.C.S.C, Beasley, Kenneth A., M.D., F.R.C.S.C, McAlister, Vivian C., M.D., F.R.C.S.C, Luke, Patrick P.W., M.D., F.R.C.S.C

“…Abstract Early renal allograft dysfunction may be caused by a number of technical factors including thrombosis, kinking of vessels, and a Page kidney situation…”
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Reduction of chronic allograft nephropathy by inhibition of extracellular signal-regulated kinase 1 and 2 signaling by Wang, Shuang, Jiang, Jifu, Guan, Qiunong, Wang, Hao, Nguan, Christopher Y C, Jevnikar, Anthony M, Du, Caigan

“…Chronic allograft nephropathy (CAN), the most common cause of late kidney allograft failure, is not effectively prevented by immunosuppressive regimens…”
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Renal artery pseudoaneurysm of infectious etiology: A life-threatening complication after renal transplantation by Nguan, Christopher Y.C., Luke, Patrick P.P.W.

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Requirement of clusterin expression for prosurvival autophagy in hypoxic kidney tubular epithelial cells by Alnasser, Hatem A, Guan, Qiunong, Zhang, Fan, Gleave, Martin E, Nguan, Christopher Y C, Du, Caigan

“…Cellular autophagy is a prosurvival mechanism in the kidney against ischemia-reperfusion injury (IRI), but the molecular pathways that activate the autophagy…”
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Late renal vein aneurysm following living related renal transplant by Dale, Robert T, Bidnur, Samir, Nguan, Christopher Y C

“…Renal vein aneurysms are rare; there are less than 10 reported cases. As of yet there have been no reported cases of renal vein aneurysm following renal…”
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Reduction of Foxp3-expressing regulatory T cell infiltrates during the progression of renal allograft rejection in a mouse model by Wang, Shuang, Jiang, Jifu, Guan, Qiunong, Lan, Zhu, Wang, Hao, Nguan, Christopher Y.C, Jevnikar, Anthony M, Du, Caigan

“…Abstract Background Regulatory T (Treg) cells are the immune suppressors in the maintenance of immune homeostasis and tolerance to self and non-self antigens,…”
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Tissue Tracking and Registration for Image-Guided Surgery by Yip, Michael C., Lowe, David G., Salcudean, Septimiu E., Rohling, Robert N., Nguan, Christopher Y.

“…Vision-based tracking of tissue is a key component to enable augmented reality during a surgical operation. Conventional tracking techniques in computer vision…”
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Reduction of chronic rejection of renal allografts by anti-transforming growth factor-β antibody therapy in a rat model by Guan, Qiunong, Li, Shuyuan, Gao, Sihai, Chen, Huifang, Nguan, Christopher Y C, Du, Caigan

“…There is no effective treatment for chronic rejection (CR) that largely limits long-term survival of kidney transplants. Transforming growth factor (TGF)-β is…”
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