Search Results - "Ngo, Quy A."

A calcium dialog mediated by the FERONIA signal transduction pathway controls plant sperm delivery by Ngo, Quy A, Vogler, Hannes, Lituiev, Dmytro S, Nestorova, Anna, Grossniklaus, Ueli

“…Sperm delivery for double fertilization of flowering plants relies on interactions between the pollen tube (PT) and two synergids, leading to programmed cell…”
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The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability by Huang, Yun, Mouttet, Brice, Warnatz, Hans-Jörg, Risch, Thomas, Rietmann, Fabian, Frommelt, Fabian, Ngo, Quy A., Dobay, Maria Pamela, Marovca, Blerim, Jenni, Silvia, Tsai, Yi-Chien, Matzk, Sören, Amstislavskiy, Vyacheslav, Schrappe, Martin, Stanulla, Martin, Gstaiger, Matthias, Bornhauser, Beat, Yaspo, Marie-Laure, Bourquin, Jean-Pierre

“…The chimeric transcription factor TCF3-HLF defines an incurable acute lymphoblastic leukemia subtype. Here we decipher the regulome of endogenous TCF3-HLF and…”
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Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivity by Manzella, Gabriele, Schreck, Leonie D., Breunis, Willemijn B., Molenaar, Jan, Merks, Hans, Barr, Frederic G., Sun, Wenyue, Römmele, Michaela, Zhang, Luduo, Tchinda, Joelle, Ngo, Quy A., Bode, Peter, Delattre, Olivier, Surdez, Didier, Rekhi, Bharat, Niggli, Felix K., Schäfer, Beat W., Wachtel, Marco

“…Cancer therapy is currently shifting from broadly used cytotoxic drugs to patient-specific precision therapies. Druggable driver oncogenes, identified by…”
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Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization by Pedot, Gloria, Marques, Joana Graça, Ambühl, Philip P, Wachtel, Marco, Kasper, Stephanie, Ngo, Quy A, Niggli, Felix K, Schäfer, Beat W

“…Oncogenic transcription factors lacking enzymatic activity or targetable binding pockets are typically considered "undruggable". An example is provided by the…”
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PAX3-FOXO1 uses its activation domain to recruit CBP/P300 and shape RNA Pol2 cluster distribution by Asante, Yaw, Benischke, Katharina, Osman, Issra, Ngo, Quy A., Wurth, Jakob, Laubscher, Dominik, Kim, Hyunmin, Udhayakumar, Bhavatharini, Khan, Md Imdadul H., Chin, Diana H., Porch, Jadon, Chakraborty, Maharshi, Sallari, Richard, Delattre, Olivier, Zaidi, Sakina, Morice, Sarah, Surdez, Didier, Danielli, Sara G., Schäfer, Beat W., Gryder, Berkley E., Wachtel, Marco

“…Activation of oncogenic gene expression from long-range enhancers is initiated by the assembly of DNA-binding transcription factors (TF), leading to…”
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CRISPR activation screen identifies TGFβ-associated PEG10 as a crucial tumor suppressor in Ewing sarcoma by Saratov, Vadim, Ngo, Quy A., Pedot, Gloria, Sidorov, Semjon, Wachtel, Marco, Niggli, Felix K., Schäfer, Beat W.

“…As the second most common pediatric bone and soft tissue tumor, Ewing sarcoma (ES) is an aggressive disease with a pathognomonic chromosomal translocation…”
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Corrigendum to "Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization" [Neoplasia volume 27 (2022) pp. 100784/Number C] by Pedot, Gloria, Marques, Joana Graça, Ambühl, Philip P, Wachtel, Marco, Kasper, Stephanie, Ngo, Quy A, Niggli, Felix K, Schäfer, Beat W

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NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency by Marques, Joana G, Gryder, Berkley E, Pavlovic, Blaz, Chung, Yeonjoo, Ngo, Quy A, Frommelt, Fabian, Gstaiger, Matthias, Song, Young, Benischke, Katharina, Laubscher, Dominik, Wachtel, Marco, Khan, Javed, Schäfer, Beat W

“…The NuRD complex subunit CHD4 is essential for fusion-positive rhabdomyosarcoma (FP-RMS) survival, but the mechanisms underlying this dependency are not…”
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Author Correction: CRISPR activation screen identifies TGFβ-associated PEG10 as a crucial tumor suppressor in Ewing sarcoma by Saratov, Vadim, Ngo, Quy A., Pedot, Gloria, Sidorov, Semjon, Wachtel, Marco, Niggli, Felix K., Schäfer, Beat W.

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Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis by Pagnussat, Gabriela C, Yu, Hee-Ju, Ngo, Quy A, Rajani, Sarojam, Mayalagu, Sevugan, Johnson, Cameron S, Capron, Arnaud, Xie, Li-Fen, Ye, De, Sundaresan, Venkatesan

“…The plant life cycle involves an alternation of generations between sporophyte and gametophyte. Currently, the genes and pathways involved in gametophytic…”
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DEFECTIVE EMBRYO AND MERISTEMS genes are required for cell division and gamete viability in Arabidopsis by Lee, Chin Hong, Hawker, Nathaniel P, Peters, Jonathan R, Lonhienne, Thierry G A, Gursanscky, Nial R, Matthew, Louisa, Brosnan, Christopher A, Mann, Christopher W G, Cromer, Laurence, Taochy, Christelle, Ngo, Quy A, Sundaresan, Venkatesan, Schenk, Peer M, Kobe, Bostjan, Borges, Filipe, Mercier, Raphael, Bowman, John L, Carroll, Bernard J

“…The DEFECTIVE EMBRYO AND MERISTEMS 1 (DEM1) gene encodes a protein of unknown biochemical function required for meristem formation and seedling development in…”
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Molecular Characterization of the glauce Mutant: A Central Cell-Specific Function Is Required for Double Fertilization in Arabidopsis by Leshem, Yehoram, Johnson, Cameron, Wuest, Samuel E., Song, Xiaoya, Ngo, Quy A., Grossniklaus, Ueli, Sundaresan, Venkatesan

“…Double fertilization of the egg cell and the central cell by two sperm cells, resulting in the formation of the embryo and the endosperm, respectively, is a…”
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The Armadillo Repeat Gene ZAK IXIK Promotes Arabidopsis Early Embryo and Endosperm Development through a Distinctive Gametophytic Maternal Effect by Ngo, Quy A., Baroux, Celia, Guthörl, Daniela, Mozerov, Peter, Collinge, Margaret A., Sundaresan, Venkatesan, Grossniklaus, Ueli

“…The proper balance of parental genomic contributions to the fertilized embryo and endosperm is essential for their normal growth and development. The…”
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The TvPirin Gene Is Necessary for Haustorium Development in the Parasitic Plant Triphysaria versicolor by Bandaranayake, Pradeepa C.G., Tomilov, Alexey, Tomilova, Natalya B., Ngo, Quy A., Wickett, Norman, dePamphilis, Claude W., Yoder, John I.

“…The rhizosphere is teemed with organisms that coordinate their symbioses using chemical signals traversing between the host root and symbionts. Chemical…”
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The differentially regulated genes TvQR1 and TvPirin of the parasitic plant Triphysaria exhibit distinctive natural allelic diversity by Ngo, Quy A, Albrecht, Huguette, Tsuchimatsu, Takashi, Grossniklaus, Ueli

“…Plant parasitism represents an extraordinary interaction among flowering plants: parasitic plants use a specialized organ, the haustorium, to invade the host…”
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Arabidopsis GLAUCE promotes fertilization-independent endosperm development and expression of paternally inherited alleles by Ngo, Quy A, Moore, James M, Baskar, Ramamurthy, Grossniklaus, Ueli, Sundaresan, Venkatesan

“…Early seed development of sexually reproducing plants requires both maternal and paternal genomes but is prominently maternally influenced. A novel…”
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The Chromatin Remodeler CHD4 Sustains Ewing Sarcoma Cell Survival by Controlling Global Chromatin Architecture by Graca Marques, Joana, Pavlovic, Blaz, Ngo, Quy A, Pedot, Gloria, Roemmele, Michaela, Volken, Larissa, Kisele, Samanta, Perbet, Romain, Wachtel, Marco, Schäfer, Beat W

“…Ewing sarcoma is an aggressive cancer with a defective response to DNA damage leading to an enhanced sensitivity to genotoxic agents. Mechanistically, Ewing…”
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Cytoplasmic Ca2+ changes dynamically during the interaction of the pollen tube with synergid cells by Iwano, Megumi, Ngo, Quy A, Entani, Tetsuyuki, Shiba, Hiroshi, Nagai, Takeharu, Miyawaki, Atsushi, Isogai, Akira, Grossniklaus, Ueli, Takayama, Seiji

“…The directional growth of the pollen tube from the stigma to the embryo sac in the ovules is regulated by pollen-pistil interactions based on intercellular…”
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Retraction notice to “Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization” [Neoplasia 27 (2022) 100784] by Pedot, Gloria, Marques, Joana Graça, Ambühl, Philip P., Wachtel, Marco, Kasper, Stephanie, Ngo, Quy A., Niggli, Felix K., Schäfer, Beat W.

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Retraction notice to Corrigendum to “Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization” [Neoplasia 31 (2022) 100805] by Pedot, Gloria, Marques, Joana Graça, Ambühl, Philip P., Wachtel, Marco, Kasper, Stephanie, Ngo, Quy A., Niggli, Felix K., Schäfer, Beat W.

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