Search Results - "Ngo, Kenneth"

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    Reduction in Human Epidermal Langerhans Cells with Age Is Associated with Decline in CXCL14-Mediated Recruitment of CD14+ Monocytes by Hasegawa, Tatsuya, Feng, Zhaoyi, Yan, Zhiyu, Ngo, Kenneth H., Hosoi, Junichi, Demehri, Shadmehr

    Published in Journal of investigative dermatology (01-07-2020)
    “…The skin provides the first line of physical and immunological defense against environmental insults. However, the age-related changes in the immune function…”
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    Journal Article
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    Acute pharmacological degradation of Helios destabilizes regulatory T cells by Wang, Eric S., Verano, Alyssa L., Nowak, Radosław P., Yuan, J. Christine, Donovan, Katherine A., Eleuteri, Nicholas A., Yue, Hong, Ngo, Kenneth H., Lizotte, Patrick H., Gokhale, Prafulla C., Gray, Nathanael S., Fischer, Eric S.

    Published in Nature chemical biology (01-06-2021)
    “…The zinc-finger transcription factor Helios is critical for maintaining the identity, anergic phenotype and suppressive activity of regulatory T (T reg )…”
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    Thymic stromal lymphopoietin blocks early stages of breast carcinogenesis by Demehri, Shadmehr, Cunningham, Trevor J, Manivasagam, Sindhu, Ngo, Kenneth H, Moradi Tuchayi, Sara, Reddy, Rasika, Meyers, Melissa A, DeNardo, David G, Yokoyama, Wayne M

    Published in The Journal of clinical investigation (01-04-2016)
    “…Advances in the field of cancer immunology, including studies on tumor-infiltrating CD8+ cytotoxic T lymphocytes (CTLs), have led to new immunotherapeutics…”
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    Chronic Inflammation Promotes Skin Carcinogenesis in Cancer-Prone Discoid Lupus Erythematosus by Zaalberg, Anniek, Moradi Tuchayi, Sara, Ameri, Amir H., Ngo, Kenneth H., Cunningham, Trevor J., Eliane, Jean-Pierre, Livneh, Maia, Horn, Thomas D., Rosman, Ilana S., Musiek, Amy, Anadkat, Milan J., Demehri, Shadmehr

    Published in Journal of investigative dermatology (01-01-2019)
    “…High-risk skin cancer is a rare, but severe, complication associated with discoid lupus erythematosus (DLE). Chronic scar, inflammation, UVR, and…”
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    Skin cancer precursor immunotherapy for squamous cell carcinoma prevention by Rosenberg, Abby R, Tabacchi, Mary, Ngo, Kenneth H, Wallendorf, Michael, Rosman, Ilana S, Cornelius, Lynn A, Demehri, Shadmehr

    Published in JCI insight (21-03-2019)
    “…Topical calcipotriol plus 5-fluorouracil (5-FU) combination is an effective immunotherapy against actinic keratosis (AK), which is a precursor to squamous cell…”
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    Cotargeting a MYC/eIF4A-survival axis improves the efficacy of KRAS inhibitors in lung cancer by Nardi, Francesca, Perurena, Naiara, Schade, Amy E, Li, Ze-Hua, Ngo, Kenneth, Ivanova, Elena V, Saldanha, Aisha, Li, Chendi, Gokhale, Prafulla C, Hata, Aaron N, Barbie, David A, Paweletz, Cloud P, Jänne, Pasi A, Cichowski, Karen

    Published in The Journal of clinical investigation (15-08-2023)
    “…Despite the success of KRAS G12C inhibitors in non-small cell lung cancer (NSCLC), more effective treatments are needed. One preclinical strategy has been to…”
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    Topical Calcipotriol Plus Imiquimod Immunotherapy for Nonkeratinocyte Skin Cancers by Azin, Marjan, Ngo, Kenneth H., Hojanazarova, Jennet, Demehri, Shadmehr

    Published in JID innovations (01-11-2023)
    “…Nonkeratinocyte cutaneous malignancies, including breast cancer cutaneous metastasis and melanoma in situ, are often poor surgical candidates. Imiquimod (IMQ),…”
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    Topical Combination of Fluorouracil and Calcipotriene as a Palliative Therapy for Refractory Extramammary Paget Disease by Molina, Gabriel E, Khalifian, Saami, Mull, Jamie L, Chen, Lu, Rosman, Ilana S, Faulkner-Jones, Beverly E, Ngo, Kenneth H, Demehri, Shadmehr, Cornelius, Lynn A, Wu, Peggy A

    Published in JAMA dermatology (Chicago, Ill.) (01-05-2019)
    “…Extramammary Paget disease (EMPD), a rare intraepithelial adenocarcinoma, poses a therapeutic challenge with high postoperative recurrence rates and a limited…”
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    Immunity to commensal papillomaviruses protects against skin cancer by Strickley, John D., Messerschmidt, Jonathan L., Awad, Mary E., Li, Tiancheng, Hasegawa, Tatsuya, Ha, Dat Thinh, Nabeta, Henry W., Bevins, Paul A., Ngo, Kenneth H., Asgari, Maryam M., Nazarian, Rosalynn M., Neel, Victor A., Jenson, Alfred Bennett, Joh, Joongho, Demehri, Shadmehr

    Published in Nature (London) (01-11-2019)
    “…Immunosuppression increases the risk of cancers that are associated with viral infection 1 . In particular, the risk of squamous cell carcinoma of the…”
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    Electrodiagnostic Findings and Surgical Outcome in Isolated First Branch Lateral Plantar Neuropathy: A Case Series With Literature Review by Ngo, Kenneth T., MD, Del Toro, David R., MD

    “…Abstract Ngo KT, Del Toro DR. Electrodiagnostic findings and surgical outcome in isolated first branch lateral plantar neuropathy: a case series with…”
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    Prevalence of Prostate Cancer in Patients With Chronic Spinal Cord Injury by Patel, Nikhil, MD, Ngo, Kenneth, MD, Hastings, James, PhD, Ketchum, Nicholas, MD, Sepahpanah, Farhad, MD

    Published in PM & R (01-07-2011)
    “…Objective To determine the prevalence of prostate cancer in patients with chronic spinal cord injury (SCI), with regard to the duration, level, and severity of…”
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