Search Results - "Ngo, Kenneth"
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Reduction in Human Epidermal Langerhans Cells with Age Is Associated with Decline in CXCL14-Mediated Recruitment of CD14+ Monocytes
Published in Journal of investigative dermatology (01-07-2020)“…The skin provides the first line of physical and immunological defense against environmental insults. However, the age-related changes in the immune function…”
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IL-33/regulatory T cell axis triggers the development of a tumor-promoting immune environment in chronic inflammation
Published in Proceedings of the National Academy of Sciences - PNAS (12-02-2019)“…Chronic inflammation’s tumor-promoting potential is well-recognized; however, the mechanism underlying the development of this immune environment is unknown…”
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Acute pharmacological degradation of Helios destabilizes regulatory T cells
Published in Nature chemical biology (01-06-2021)“…The zinc-finger transcription factor Helios is critical for maintaining the identity, anergic phenotype and suppressive activity of regulatory T (T reg )…”
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Thymic stromal lymphopoietin blocks early stages of breast carcinogenesis
Published in The Journal of clinical investigation (01-04-2016)“…Advances in the field of cancer immunology, including studies on tumor-infiltrating CD8+ cytotoxic T lymphocytes (CTLs), have led to new immunotherapeutics…”
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Chronic Inflammation Promotes Skin Carcinogenesis in Cancer-Prone Discoid Lupus Erythematosus
Published in Journal of investigative dermatology (01-01-2019)“…High-risk skin cancer is a rare, but severe, complication associated with discoid lupus erythematosus (DLE). Chronic scar, inflammation, UVR, and…”
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Skin cancer precursor immunotherapy for squamous cell carcinoma prevention
Published in JCI insight (21-03-2019)“…Topical calcipotriol plus 5-fluorouracil (5-FU) combination is an effective immunotherapy against actinic keratosis (AK), which is a precursor to squamous cell…”
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EGFR Inhibition Enhances the Cellular Uptake and Antitumor-Activity of the HER3 Antibody-Drug Conjugate HER3-DXd
Published in Cancer research (Chicago, Ill.) (01-01-2022)“…Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) are the standard-of-care treatment for -mutant non-small cell lung cancers (NSCLC)…”
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Cotargeting a MYC/eIF4A-survival axis improves the efficacy of KRAS inhibitors in lung cancer
Published in The Journal of clinical investigation (15-08-2023)“…Despite the success of KRAS G12C inhibitors in non-small cell lung cancer (NSCLC), more effective treatments are needed. One preclinical strategy has been to…”
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Topical Calcipotriol Plus Imiquimod Immunotherapy for Nonkeratinocyte Skin Cancers
Published in JID innovations (01-11-2023)“…Nonkeratinocyte cutaneous malignancies, including breast cancer cutaneous metastasis and melanoma in situ, are often poor surgical candidates. Imiquimod (IMQ),…”
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Topical Combination of Fluorouracil and Calcipotriene as a Palliative Therapy for Refractory Extramammary Paget Disease
Published in JAMA dermatology (Chicago, Ill.) (01-05-2019)“…Extramammary Paget disease (EMPD), a rare intraepithelial adenocarcinoma, poses a therapeutic challenge with high postoperative recurrence rates and a limited…”
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Immunity to commensal papillomaviruses protects against skin cancer
Published in Nature (London) (01-11-2019)“…Immunosuppression increases the risk of cancers that are associated with viral infection 1 . In particular, the risk of squamous cell carcinoma of the…”
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Aggressive Mobilization in Disorders of Consciousness During Acute Rehabilitation: An Untapped Intervention
Published in Archives of physical medicine and rehabilitation (01-10-2014)Get full text
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Electrodiagnostic Findings and Surgical Outcome in Isolated First Branch Lateral Plantar Neuropathy: A Case Series With Literature Review
Published in Archives of physical medicine and rehabilitation (01-12-2010)“…Abstract Ngo KT, Del Toro DR. Electrodiagnostic findings and surgical outcome in isolated first branch lateral plantar neuropathy: a case series with…”
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Prevalence of Prostate Cancer in Patients With Chronic Spinal Cord Injury
Published in PM & R (01-07-2011)“…Objective To determine the prevalence of prostate cancer in patients with chronic spinal cord injury (SCI), with regard to the duration, level, and severity of…”
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Poster 45: Failure to Identify Intrathecal Baclofen Pump/Catheter Problems Can Lead to Unnecessary Healthcare Costs: A Case Report
Published in PM & R (01-09-2009)Get full text
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Neuromuscular Electrical Stimulation Protocol to Improve Blepharoptosis Following Traumatic Cculomotor Nerve Palsy
Published in Archives of physical medicine and rehabilitation (01-10-2016)Get full text
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Poster 353: Prostate Cancer in Patients with Chronic Spinal Cord Injury
Published in PM & R (01-09-2009)Get full text
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