Search Results - "Ngo, Doan"

Established and Emerging Cancer Therapies and Cardiovascular System: Focus on Hypertension—Mechanisms and Mitigation by Butel-Simoes, Lloyd E., Haw, Tatt Jhong, Williams, Trent, Sritharan, Shanathan, Gadre, Payal, Herrmann, Sandra M., Herrmann, Joerg, Ngo, Doan T.M., Sverdlov, Aaron L.

“…Cardiovascular disease and cancer are 2 of the leading causes of death worldwide. Although improvements in outcomes have been noted for both disease entities,…”
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Biology and therapeutic implications of VEGF‐A splice isoforms and single‐nucleotide polymorphisms in colorectal cancer by Canavese, Miriam, Ngo, Doan T.M., Maddern, Guy J., Hardingham, Jennifer E., Price, Timothy J., Hauben, Ehud

“…Tumor growth, dissemination and metastasis are dependent on angiogenesis. The predominant vascular endothelial growth factor (VEGF) isoform that plays a major…”
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Mitochondrial Dynamin-Related Protein Drp1: a New Player in Cardio-oncology by Deng, Yali, Ngo, Doan T. M., Holien, Jessica K., Lees, Jarmon G., Lim, Shiang Y.

“…Purpose of Review This study is aimed at reviewing the recent progress in Drp1 inhibition as a novel approach for reducing doxorubicin-induced cardiotoxicity…”
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New cimlanod trial provides insights into mechanistic effects of vasodilators in heart failure by Collins, Nicholas J., Ngo, Doan T.M., Sverdlov, Aaron L.

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Forkhead Box O-1 Modulation Improves Endothelial Insulin Resistance in Human Obesity by Karki, Shakun, Farb, Melissa G, Ngo, Doan T.M, Myers, Samantha, Puri, Vishwajeet, Hamburg, Naomi M, Carmine, Brian, Hess, Donald T, Gokce, Noyan

“…OBJECTIVE—Increased visceral adiposity has been closely linked to insulin resistance, endothelial dysfunction, and cardiometabolic disease in obesity, but…”
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The Role of Pathological Aging in Cardiac and Pulmonary Fibrosis by Murtha, Lucy A, Morten, Matthew, Schuliga, Michael J, Mabotuwana, Nishani S, Hardy, Sean A, Waters, David W, Burgess, Janette K, Ngo, Doan Tm, Sverdlov, Aaron L, Knight, Darryl A, Boyle, Andrew J

“…Aging promotes a range of degenerative pathologies characterized by progressive losses of tissue and/or cellular function. Fibrosis is the hardening,…”
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Vitamin D supplementation lowers thrombospondin-1 levels and blood pressure in healthy adults by Amarasekera, Anjalee T, Assadi-Khansari, Bahador, Liu, Saifei, Black, Marilyn, Dymmott, Greer, Rogers, Natasha M, Sverdlov, Aaron L, Horowitz, John D, Ngo, Doan T M

“…Vitamin D insufficiency, defined as 25-hydroxyvitamin D (25(OH)D) levels < 75nmol/L is associated with cardio-metabolic dysfunction. Vitamin D insufficiency is…”
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Sex-based differences in short- and longer-term diet-induced metabolic heart disease by Croft, Amanda J, Kelly, Conagh, Chen, Dongqing, Haw, Tatt Jhong, Balachandran, Lohis, Murtha, Lucy A, Boyle, Andrew J, Sverdlov, Aaron L, Ngo, Doan T M

“…Sex-based differences in the development of obesity-induced cardiometabolic dysfunction are well documented, however, the specific mechanisms are not…”
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Noncanonical Wnt signaling promotes obesity-induced adipose tissue inflammation and metabolic dysfunction independent of adipose tissue expansion by Fuster, José J, Zuriaga, María A, Ngo, Doan Thi-Minh, Farb, Melissa G, Aprahamian, Tamar, Yamaguchi, Terry P, Gokce, Noyan, Walsh, Kenneth

“…Adipose tissue dysfunction plays a pivotal role in the development of insulin resistance in obese individuals. Cell culture studies and gain-of-function mouse…”
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The Importance of Primary Care in Cardio-Oncology by Cehic, Daniel A., Sverdlov, Aaron L., Koczwara, Bogda, Emery, Jon, Ngo, Doan T. M., Thornton-Benko, Elysia

“…Opinion statement There is significant interplay between cancer and cardiovascular disease involving shared risk factors, cross disease communication where…”
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An antiangiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease by Kikuchi, Ryosuke, Nakamura, Kazuto, MacLauchlan, Susan, Ngo, Doan Thi-Minh, Shimizu, Ippei, Fuster, Jose Javier, Katanasaka, Yasufumi, Yoshida, Sumiko, Qiu, Yan, Yamaguchi, Terry P, Matsushita, Tadashi, Murohara, Toyoaki, Gokce, Noyan, Bates, David O, Hamburg, Naomi M, Walsh, Kenneth

“…Alternative splicing of the gene encoding VEGF-A under ischemic conditions generates an antiangiogenic isoform of the protein that impairs revascularization…”
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Oxidative modifications of mitochondrial complex II are associated with insulin resistance of visceral fat in obesity by Ngo, Doan T M, Sverdlov, Aaron L, Karki, Shakun, Macartney-Coxson, Donia, Stubbs, Richard S, Farb, Melissa G, Carmine, Brian, Hess, Donald T, Colucci, Wilson S, Gokce, Noyan

“…Obesity, particularly visceral adiposity, has been linked to mitochondrial dysfunction and increased oxidative stress, which have been suggested as mechanisms…”
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Landscape fire smoke airway exposure impairs respiratory and cardiac function and worsens experimental asthma by Gomez, Henry M., Haw, Tatt J., Ilic, Dusan, Robinson, Peter, Donovan, Chantal, Croft, Amanda J., Vanka, Kanth S., Small, Ellen, Carroll, Olivia R., Kim, Richard Y., Mayall, Jemma R., Beyene, Tesfalidet, Palanisami, Thava, Ngo, Doan T.M., Zosky, Graeme R., Holliday, Elizabeth G., Jensen, Megan E., McDonald, Vanessa M., Murphy, Vanessa E., Gibson, Peter G., Horvat, Jay C.

“…[Display omitted] Millions of people are exposed to landscape fire smoke (LFS) globally, and inhalation of LFS particulate matter (PM) is associated with poor…”
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How to build an actionable narrative for cardio-oncology by Nolan, Mark T., Ngo, Doan T.M., Sverdlov, Aaron L.

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Testosterone to estradiol ratio and plaque inflammation: mechanistic insights and biomarker potential? by Figtree, Gemma A, Ngo, Doan T M, Bubb, Kristen J

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Cancer Therapies and Cardiomyocyte Viability: Which Drugs are Directly Cardiotoxic? by Balachandran, Lohis, Haw, Tatt Jhong, Leong, Angeline Jia Wen, Croft, Amanda J., Chen, Dongqing, Kelly, Conagh, Sverdlov, Aaron L., Ngo, Doan T.M.

“…Increased cancer survivorship represents a remarkable achievement for modern medicine. Unfortunately, cancer treatments have inadvertently contributed to…”
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Response to the letter to editor : Galectin-3 and atrial fibrillation by Sverdlov, Aaron L, Ngo, Doan T.M

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Does Vitamin D Modulate Asymmetric Dimethylarginine and C-Reactive Protein Concentrations? by Ngo, Doan T., BPharm, PhD, Sverdlov, Aaron L., MBBS, McNeil, John J., MBBS, PhD, Horowitz, John D., MBBS, PhD

“…Abstract Background Vitamin D deficiency is associated with significant increases in the incidence of cardiovascular risk factors and mortality. However, the…”
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Overexpression of Mitochondrial Catalase within Adipose Tissue Does Not Confer Systemic Metabolic Protection against Diet-Induced Obesity by Croft, Amanda J, Kelly, Conagh, Chen, Dongqing, Haw, Tatt Jhong, Sverdlov, Aaron L, Ngo, Doan T M

“…Obesity is associated with significant metabolic co-morbidities, such as diabetes, hypertension, and dyslipidaemia, as well as a range of cardiovascular…”
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Reciprocal regulation of NO signaling and TXNIP expression in humans: Impact of aging and ramipril therapy by Sverdlov, Aaron L, Chan, Wai P.A, Procter, Nathan E.K, Chirkov, Yuliy Y, Ngo, Doan T.M, Horowitz, John D

“…Abstract Background Impaired tissue responsiveness to nitric oxide (NO) occurs in many cardiovascular diseases as well as with advanced age and is a correlate…”
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