Search Results - "Ngemenya, Moses N."

New antimalarial hits from Dacryodes edulis (Burseraceae)--part I: isolation, in vitro activity, in silico "drug-likeness" and pharmacokinetic profiles by Zofou, Denis, Tematio, Esther Laure, Ntie-Kang, Fidele, Tene, Mathieu, Ngemenya, Moses N, Tane, Pierre, Titanji, Vincent P K

“…The aims of the present study were to identify the compounds responsible for the anti-malarial activity of Dacryoedes edulis (Burseraceae) and to investigate…”
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Hypericum lanceolatum (Hypericaceae) as a potential source of new anti-malarial agents: a bioassay-guided fractionation of the stem bark by Zofou, Denis, Kowa, Théodora K, Wabo, Hippolyte K, Ngemenya, Moses N, Tane, Pierre, Titanji, Vincent P K

“…Malaria is a major public health threat in Africa, and traditional medicine continues to play a key role in its control especially in rural areas. A…”
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Structurally simple synthetic 1, 4-disubstituted piperidines with high selectivity for resistant Plasmodium falciparum by Ngemenya, Moses N, Abwenzoh, Grace Ntube, Ikome, Hermia Nalova, Zofou, Denis, Ntie-Kang, Fidele, Efange, Simon M N

“…Emergence of resistance to artemisinins and some of their combinations in chemotherapy of clinical malaria has intensified the search for novel safe…”
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In vitro antiplasmodial activity and cytotoxicity of crude extracts and compounds from the stem bark of Kigelia africana (Lam.) Benth (Bignoniaceae) by Zofou, Denis, Kengne, Archile Bernabe Ouambo, Tene, Mathieu, Ngemenya, Moses N., Tane, Pierre, Titanji, Vincent P. K.

“…In order to assess the potential of the stem bark of Kigelia africana (Lam.) Benth as source of new anti-malarial leads, n-hexane and ethyl acetate (EtOAc)…”
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Bioassay-guided discovery of antibacterial agents: in vitro screening of Peperomia vulcanica, Peperomia fernandopoioana and Scleria striatinux by Mbah, James A, Ngemenya, Moses N, Abawah, Ashime Louis, Babiaka, Smith B, Nubed, Lina N, Nyongbela, Kennedy D, Lemuh, Njimoh Dieudonne, Efange, Simon M N

“…The global burden of bacterial infections is high and has been further aggravated by increasing resistance to antibiotics. In the search for novel…”
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Evaluation of macrofilaricidal and microfilaricidal activities against Onchocerca ochengi and cytotoxicity of some synthesized azo compounds containing thiophene backbone by Tsemeugne, Joseph, Shinyuy, Lahngong M., Djeukoua, Sorel K. D., Sopbue, Emmanuel F., Ngemenya, Moses N.

“…Control and treatment of onchocerciasis, a devastating tropical filarial disease caused by Onchocerca volvulus , rely solely on the community directed…”
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In vitro activity against multi-drug resistant bacteria and cytotoxicity of lichens collected from Mount Cameroon by Bate, Petuel Ndip Ndip, Orock, Ayuk Elizabeth, Nyongbela, Kennedy Dohjinga, Babiaka, Smith Borakaeyabe, Kukwah, Anthony, Ngemenya, Moses N.

“…Natural products remain a promising source of new efficacious antimicrobials to counter increasing resistance and prevent emergence of multidrug and…”
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Anti-Salmonella activity on multidrug-resistant strains and cytotoxicity of extracts and constituents of Garcinia brevipedicellata and Garcinia epunctata by Akongwi, Mirabel, Kwene, Emade C., Awah, Laupy Anne, Tih, Anastasie E., Ghogomu, Raphael T., Cho-Ngwa, Fidelis, Ngemenya, Moses N.

“…The morbidity of Salmonella infections remains high partly due to emergence of multidrug-resistant (MDR) strains. Garcinia species have demonstrated activity…”
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Selective activity of extracts of Margaritaria discoidea and Homalium africanum on Onchocerca ochengi by Cho-Ngwa, Fidelis, Abongwa, Melanie, Ngemenya, Moses N, Nyongbela, Kennedy D

“…The current treatment of onchocerciasis relies on the use of ivermectin which is only microfilaricidal and for which resistant parasite strains of veterinary…”
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The antimalarial potential of medicinal plants used for the treatment of malaria in Cameroonian folk medicine by Titanji, Vincent P K, Zofou, Denis, Ngemenya, Moses N

“…Malaria remains one of the leading public health problems in Cameroon as in other parts of Sub-Saharan Africa. In the past decades, this situation has been…”
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In vitro antifungal, antibacterial activities and nutritional value of nine Cameroonian edible vegetables by Wandji, Fabrice N B, Achidi, Aduni U, Ngemenya, Moses N, Nyongbela, Kennedy D, Tiencheu, Bernard

“…The high medicinal potential of plants, including edible vegetables, is well documented. Vegetables can afford significant health benefits to consumers,…”
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Promising activity of tetrahydroisoquinolines against multidrug-resistant clinical Salmonella isolates and cytotoxicity against monkey kidney cells by Hanna, Joelle Ngo, Ndip, Rita A., Ngemenya, Moses N., Simons, Casey R., Toze, Flavien A. A., Ghogomu, Stephen M., Mbah, James A.

“…The high burden of Salmonella infections has been aggravated by the emergence and spread of multidrug-resistant strains affecting almost all antibiotic classes…”
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Isolation and identification of an antiparasitic triterpenoid estersaponin from the stem bark of Pittosporum mannii (Pittosporaceae) by Nyongbela, Kennedy D, Lannang, Alain M, Ayimele, Godfred A, Ngemenya, Moses N, Bickle, Quentin, Efange, Simon

“…To screen for antiparasitic properties of Pittosporum mannii Hook (Pittosporaceae) through in vitro bioassay tests and to identify the bioactive compound(s)…”
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4-aroylpiperidines and 4-(α-hydroxyphenyl)piperidines as selective sigma-1 receptor ligands: synthesis, preliminary pharmacological evaluation and computational studies by Ikome, Hermia N., Ntie-Kang, Fidele, Ngemenya, Moses N., Tu, Zhude, Mach, Robert H., Efange, Simon M. N.

“…Background Sigma (σ) receptors are membrane-bound proteins characterised by an unusual promiscuous ability to bind a wide variety of drugs and their high…”
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In Vitro Antiplasmodial Activity and Cytotoxicity of Extracts of Selected Medicinal Plants Used by Traditional Healers of Western Cameroon by Zofou, Denis, Tene, Mathieu, Ngemenya, Moses N., Tane, Pierre, Titanji, Vincent P. K.

“…Medicinal plants play a key role in malaria control in Africa, especially in remote areas where health facilities are limited. In order to assess their…”
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Antiplasmodial Activities of Some Products from Turreanthus Africanus (Meliaceae) by Ngemenya, Moses N, Akam, Thomas M, Yong, Joseph N, Tane, Pierre, Fanso-Free, Samuel N. Y, Berzins, Klavs, Titanji, Vincent P. K

“…We investigated the antiplasmodial activity of some pure compounds of Turreanthus africanus (Meliaceae), a plant that is used in traditional medicine to treat…”
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In vitro antiplasmodial activity and cytotoxicity of crude extracts and compounds from the stem bark of Kigelia africana by Zofou, Denis, Ouambo Kengne, Archile Bernabe, Tene, Mathieu, Ngemenya, Moses N, Tane, Pierre, Titanji, Vincent P.K

“…In order to assess the potential of the stem bark of Kigelia africana (Lam.) Benth as source of new anti-malarial leads, n-hexane and ethyl acetate (EtOAc)…”
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Ethnobotanical survey and in vitro antiplasmodial activity of medicinal plants used to treat malaria in Kagera and Lindi regions, Tanzania by Ramadhani, S.O. Nondo, Denis, Zofou, Mainen, J. Moshi, Paul, Erasto, Samuel, Wanji, Moses, N. Ngemenya, Vincent, P.K. Titanji, Abdul, W. Kidukuli, Pax, J. Masimba

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The Antimalarial Potential Of Medicinal Plants Used For The Treatment Of Malaria In Cameroonian Folk Medicine by Titanji, Vincent P.K, Zofou, Denis, Ngemenya, Moses N

“…Malaria remains one of the leading public health problems in Cameroon as in other parts of Sub-Saharan Africa. In the past decades, this situation has been…”
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