Search Results - "Ng, Tzi Bun"
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The medicinal and pharmaceutical importance of Dendrobium species
Published in Applied Microbiology and Biotechnology (01-03-2017)“…Plants of the Dendrobium genus, one of the largest in the Orchidaceae, manifest a diversity of medicinal effects encompassing antiangiogenic, immunomodulating,…”
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Laccases: Production, Expression Regulation, and Applications in Pharmaceutical Biodegradation
Published in Frontiers in microbiology (16-05-2017)“…Laccases are a family of copper-containing oxidases with important applications in bioremediation and other various industrial and biotechnological areas…”
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3
Shiga toxins: from structure and mechanism to applications
Published in Applied microbiology and biotechnology (01-02-2016)“…Shiga toxins are a group of type 2 ribosome-inactivating proteins (RIPs) produced in several types of bacteria. The toxins possess an AB 5 structure, which…”
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4
Mushroom extracts and compounds with suppressive action on breast cancer: evidence from studies using cultured cancer cells, tumor-bearing animals, and clinical trials
Published in Applied microbiology and biotechnology (01-06-2020)“…This article reviews mushrooms with anti-breast cancer activity. The mushrooms covered which are better known include the following: button mushroom Agaricus…”
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New ribosome-inactivating proteins and other proteins with protein synthesis–inhibiting activities
Published in Applied microbiology and biotechnology (01-05-2020)“…Ribosome-inactivating proteins (RIPs) consist of three varieties. Type 1 RIPs are single-chained and approximately 30-kDa in molecular weight. Type 2 RIPs are…”
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6
Mannose Binding Lectin: A Potential Biomarker for Many Human Diseases
Published in Current medicinal chemistry (01-10-2016)“…The innate immune system plays a modulatory role in producing an inflammatory response during microbial infection and tissue regeneration. Mannose-binding…”
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Antifreeze Proteins from Diverse Organisms and their Applications: An Overview
Published in Current protein & peptide science (01-01-2017)“…Antifreeze proteins are ice-binding or ice-structuring proteins that prevent water from freezing by adsorbing to the ice surface and stopping the growth of…”
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The effect of exogenous melatonin on reducing scoliotic curvature and improving bone quality in melatonin-deficient C57BL/6J mice
Published in Scientific reports (17-04-2019)“…It is well-documented that melatonin deficiency has been linked to the etiopathogenesis of adolescent idiopathic scoliosis. In this study, we intended to apply…”
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The mechanism of enriched environment repairing the learning and memory impairment in offspring of prenatal stress by regulating the expression of activity-regulated cytoskeletal-associated and insulin-like growth factor-2 in hippocampus
Published in Environmental health and preventive medicine (15-01-2021)“…Prenatal stress can cause neurobiological and behavioral defects in offspring; environmental factors play a crucial role in regulating the development of brain…”
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10
Anti-Parkinsonian drug discovery from herbal medicines: What have we got from neurotoxic models?
Published in Journal of ethnopharmacology (15-02-2012)“…Herbal medicines are used to treat Parkinson's disease (PD) in ancient medical systems in Asian countries such as India, China, Japan and Korea based on their…”
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Cathelicidins: peptides with antimicrobial, immunomodulatory, anti-inflammatory, angiogenic, anticancer and procancer activities
Published in Current protein & peptide science (01-09-2013)“…The family of peptides designated as cathelicidins was identified over a decade ago. Cathelicidins have since gained increasing recognition, both as endogenous…”
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12
Degradation of dyes using crude extract and a thermostable and pH-stable laccase isolated from Pleurotus nebrodensis
Published in Bioscience reports (01-08-2016)“…Three laccase isoenzymes (Lac1, Lac2 and Lac3) have been purified to homogeneity from Pleurotus nebrodensis in our previous study. Lac2 was shown to be the…”
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13
Degradation of tetracycline by immobilized laccase and the proposed transformation pathway
Published in Journal of hazardous materials (15-01-2017)“…•Laccase was immobilized as magnetic cross-linked enzyme aggregates (M-CLEAs).•Laccase at 40U/mL eliminated over 80μg/mL TC at pH 6 and 25°C in 12h.•A…”
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CRISPR/Cas9 Technology Targeting Fas Gene Protects Mice From Concanavalin‐A Induced Fulminant Hepatic Failure
Published in Journal of cellular biochemistry (01-03-2017)“…ABSTRACT Fulminant hepatic failure is a life‐threatening disease which occurs in patients without preexisting liver disease. Nowadays, there is no ideal…”
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Intestinal absorption and bioavailability of traditional Chinese medicines: a review of recent experimental progress and implication for quality control
Published in Journal of pharmacy and pharmacology (01-05-2013)“…Objectives Experimental studies on the pharmacokinetics of traditional Chinese medicines (TCMs) have achieved great progress in recent years. This review aims…”
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Studies on anticancer activities of lactoferrin and lactoferricin
Published in Current protein & peptide science (01-09-2013)“…This review mainly summarizes results of recent studies on the anticancer activity of the multifunctional protein lactoferrin (Lf) and its derived peptide…”
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First report of a haemagglutinin-induced apoptotic pathway in breast cancer cells
Published in Bioscience reports (01-10-2010)“…A dimeric 64 kDa HA (haemagglutinin) was isolated with a high yield from dried Phaseolus vulgaris cultivar 'French bean number 35' seeds. It inhibited the…”
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A Phytase Characterized by Relatively High pH Tolerance and Thermostability from the Shiitake Mushroom Lentinus edodes
Published in BioMed research international (01-01-2013)“…A monomeric phytase with a molecular mass of 14 kDa was acquired from fresh fruiting bodies of the shiitake mushroom Lentinus edodes. The isolation procedure…”
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Abnormal response of the proliferation and differentiation of growth plate chondrocytes to melatonin in adolescent idiopathic scoliosis
Published in International journal of molecular sciences (25-09-2014)“…Abnormalities in the melatonin signaling pathway and the involvement of melatonin receptor MT2 have been reported in patients with adolescent idiopathic…”
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Sesquin, a potent defensin-like antimicrobial peptide from ground beans with inhibitory activities toward tumor cells and HIV-1 reverse transcriptase
Published in Peptides (New York, N.Y. : 1980) (01-07-2005)“…An antifungal peptide with a molecular mass around 7 kDa and an N-terminal sequence highly homologous to defensin was isolated from ground beans ( Vigna…”
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