Search Results - "Ng, Siew Hon"

Solidified saturated fats coating subunit vaccines greatly extended vaccine booster release and contributed to a Th1/Th2 mixed immune response in mice by Choudhary, Pooja, Boamah, Bright, Hon Ng, Siew, White, Aaron, Weber, Lynn P., Wilson, Heather L.

“…Delayed release of vaccine coupled with a soluble vaccine acts as a primer and a booster with only a single administration, which would be very beneficial to…”
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Vaccination with a Lawsonia intracellularis subunit water in oil emulsion vaccine mitigated some disease parameters but failed to affect shedding by Fourie, Kezia R., Jeffery, Alison, Chand, Dylan, Choudhary, Pooja, Ng, Siew Hon, Liu, Haoming, Magloire, Donaldson, Khatooni, Zahed, Berberov, Emil, Wilson, Heather L.

“…Lawsonia intracellularis is the causative agent of ileitis in swine that manifests as slower weight gain, mild or hemorrhagic diarrhea and/or death in severe…”
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Metabolic engineering of Pichia pastoris to produce ricinoleic acid, a hydroxy fatty acid of industrial importance[S] by Meesapyodsuk, Dauenpen, Chen, Yan, Ng, Siew Hon, Chen, Jianan, Qiu, Xiao

“…Ricinoleic acid (12-hydroxyoctadec-cis-9-enoic acid) has many specialized uses in bioproduct industries, while castor bean is currently the only commercial…”
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Immunoproteomic analysis of Lawsonia intracellularis identifies candidate neutralizing antibody targets for use in subunit vaccine development by Obradovic, Milan, Pasternak, J. Alex, Hon Ng, Siew, Allan, Brenda, Brownlie, Robert, Wilson, Heather L.

“…•We used proteomic analysis to identify immunogenic Lawsonia intracellularis proteins.•Four immunogenic bacterial proteins predicted to be expressed on the…”
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Development of flow cytometry based adherence assay for Neisseria gonorrhoeae using 5'-carboxyfluorosceinsuccidyl ester by Thakur, Sidharath Dev, Obradovic, Milan, Dillon, Jo-Anne R, Ng, Siew Hon, Wilson, Heather L

“…Neisseria gonorrhoeae is an obligate human pathogen and its adherence to host cells is essential for its pathogenesis. Gonococcal adherence assays are based on…”
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Assessment of Immunological Response and Impacts on Fertility Following Intrauterine Vaccination Delivered to Swine in an Artificial Insemination Dose by Hamonic, Glenn, Pasternak, J Alex, Ng, Siew Hon, Fourie, Kezia R, Simko, Olena M, Deluco, Brodie, Wilson, Heather L

“…To protect the health of sows and gilts, significant investments are directed toward the development of vaccines against infectious agents that impact…”
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A single, low dose oral antigen exposure in newborn piglets primes mucosal immunity if administered with CpG oligodeoxynucleotides and polyphosphazene adjuvants by Pasternak, J. Alex, Ng, Siew Hon, Wilson, Heather L.

“…•Neonatal piglets drenched with ovalbumin alone fail to respond to oral booster immunization with immunity.•Neonatal piglets drenched with ovalbumin respond to…”
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Combination of Innate Immune Modulators as Vaccine Adjuvants in Mice by Haddadi, Azita, Chaffey, Alyssa, Ng, Siew Hon, Yalamati, Damayanthi, Wilson, Heather L

“…The development of new, effective, and safe vaccines necessarily requires the identification of new adjuvant(s) to enhance the potency and longevity of…”
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A Single-Dose Intramuscular Nanoparticle Vaccine With or Without Prior Intrauterine Priming Triggers Specific Uterine and Colostral Mucosal Antibodies and Systemic Immunity in Gilts but Not Passive Protection for Suckling Piglets by Choudhary, Pooja, Khajavinia, Amir, Mohammadi, Ramin, Ng, Siew Hon, Bérubé, Nathalie, Yalamati, Damayanthi, Haddadi, Azita, Wilson, Heather L.

“…An effective single-dose vaccine that protects the dam and her suckling offspring against infectious disease would be widely beneficial to livestock animals…”
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Evaluation of immunogenicity and protection mediated by Lawsonia intracellularis subunit vaccines by Fourie, Kezia R., Choudhary, Pooja, Ng, Siew Hon, Obradovic, Milan, Brownlie, Robert, Anand, Sanjeev K., Wilson, Heather L.

“…Lawsonia intracellularis is an economically important bacterium that causes ileitis in pigs. Current vaccines for L. intracellularis do not allow for…”
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Corrigendum to “A single, low dose oral antigen exposure in newborn piglets primes mucosal immunity if administered with CpG oligodeoxynucleotides and polyphosphazene adjuvants” [Vet. Immunol. Immunopathol. 161 (2014) 211–221] by Alex Pasternak, J., Ng, Siew Hon, Wilson, Heather L.

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Use of flow cytometry and PCR analysis to detect 5-carboxyfluoroscein-stained obligate intracellular bacteria Lawsonia intracellularis invasion of McCoy cells by Obradovic, Milan, Pasternak, J. Alex, Ng, Siew Hon, Wilson, Heather L.

“…In this study, we describe a method to quantify invasion of obligate intracellular bacteria, Lawsonia intracellularis, inside McCoy cells. In immunological…”
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Oral antigen exposure in newborn piglets circumvents induction of oral tolerance in response to intraperitoneal vaccination in later life by Pasternak, J Alex, Ng, Siew Hon, Buchanan, Rachelle M, Mertins, Sonja, Mutwiri, George K, Gerdts, Volker, Wilson, Heather L

“…BACKGROUND: We previously determined that newborn piglets orally gavaged with Ovalbumin (OVA) responded to systemic OVA re-exposure with tolerance; if…”
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Rapamune Does Not Attenuate High Cholesterol-Induced Atherosclerosis in Rabbits by Attia, Ahmed, Ahmed, Mohamed, Ng, Siew Hon, Prasad, Kailash, Shoker, Ahmed

“…Abstract Solid-organ transplant recipients are prone to develop atherosclerosis. The objectives of this study were to investigate the effects of Rapamune…”
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