Search Results - "Ng, Siemon H S"

The MEF2A transcription factor interactome in cardiomyocytes by Moustafa, Amira, Hashemi, Sara, Brar, Gurnoor, Grigull, Jörg, Ng, Siemon H. S., Williams, Declan, Schmitt-Ulms, Gerold, McDermott, John C.

“…Transcriptional regulators encoded by the M yocyte E nhancer F actor 2 (MEF2) gene family play a fundamental role in cardiac development, homeostasis and…”
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The recombinational anatomy of a mouse chromosome by Paigen, Kenneth, Szatkiewicz, Jin P, Sawyer, Kathryn, Leahy, Nicole, Parvanov, Emil D, Ng, Siemon H S, Graber, Joel H, Broman, Karl W, Petkov, Petko M

“…Among mammals, genetic recombination occurs at highly delimited sites known as recombination hotspots. They are typically 1-2 kb long and vary as much as a…”
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Trans-regulation of mouse meiotic recombination hotspots by Rcr1 by Parvanov, Emil D, Ng, Siemon H S, Petkov, Petko M, Paigen, Kenneth

“…Meiotic recombination is required for the orderly segregation of chromosomes during meiosis and for providing genetic diversity among offspring. Among mammals,…”
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Sensitivity and breadth of detection of high-throughput sequencing for adventitious virus detection by Charlebois, Robert L., Sathiamoorthy, Sarmitha, Logvinoff, Carine, Gisonni-Lex, Lucy, Mallet, Laurent, Ng, Siemon H. S.

“…High-throughput sequencing (HTS) is capable of broad virus detection encompassing both known and unknown adventitious viruses in a variety of sample matrices…”
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A Multicenter Study To Evaluate the Performance of High-Throughput Sequencing for Virus Detection by Khan, Arifa S, Ng, Siemon H S, Vandeputte, Olivier, Aljanahi, Aisha, Deyati, Avisek, Cassart, Jean-Pol, Charlebois, Robert L, Taliaferro, Lanyn P

“…The capability of high-throughput sequencing (HTS) for detection of known and unknown viruses makes it a powerful tool for broad microbial investigations, such…”
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Report of the third conference on next-generation sequencing for adventitious virus detection in biologics for humans and animals by Khan, Arifa S., Mallet, Laurent, Blümel, Johannes, Cassart, Jean-Pol, Knezevic, Ivana, Ng, Siemon H.S., Wall, Michael, Jakava-Viljanen, Miia, Logvinoff, Carine, Goios, Ana, Neels, Pieter

“…Next-generation sequencing (NGS) has been proven to address some of the limitations of the current testing methods for adventitious virus detection in…”
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Report of the 2019 NIST-FDA workshop on standards for next generation sequencing detection of viral adventitious agents in biologics and biomanufacturing by Cleveland, Megan H., Anekella, Bharathi, Brewer, Michael, Chin, Pei-Ju, Couch, Heather, Delwart, Eric, Huggett, Jim, Jackson, Scott, Martin, Javier, Monpoeho, Serge, Morrison, Tom, Ng, Siemon H.S., Ussery, David, Khan, Arifa S.

“…Adventitious virus testing assures product safety by demonstrating the absence of viruses that could be unintentionally introduced during the manufacturing…”
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Selection and evaluation of an efficient method for the recovery of viral nucleic acids from complex biologicals by Sathiamoorthy, Sarmitha, Malott, Rebecca J., Gisonni-Lex, Lucy, Ng, Siemon H. S.

“…There is a need for a broad and efficient testing strategy for the detection of both known and novel viral adventitious agents in vaccines and biologicals…”
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A physical map of the genome of Atlantic salmon, Salmo salar by Ng, Siemon H.S., Artieri, Carlo G., Bosdet, Ian E., Chiu, Readman, Danzmann, Roy G., Davidson, William S., Ferguson, Moira M., Fjell, Christopher D., Hoyheim, Bjorn, Jones, Steven J.M., de Jong, Pieter J., Koop, Ben F., Krzywinski, Martin I., Lubieniecki, Krzysztof, Marra, Marco A., Mitchell, Leslie A., Mathewson, Carrie, Osoegawa, Kazutoyo, Parisotto, Sarah E., Phillips, Ruth B., Rise, Matthew L., von Schalburg, Kristian R., Schein, Jacqueline E., Shin, Heesun, Siddiqui, Asim, Thorsen, Jim, Wye, Natasja, Yang, George, Zhu, Baoli

“…A physical map of the Atlantic salmon ( Salmo salar) genome was generated based on HindIII fingerprints of a publicly available BAC (bacterial artificial…”
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Sensitivity and breadth of detection of high-throughput sequencing for adventitious virus detection by Charlebois, Robert L, Sathiamoorthy, Sarmitha, Logvinoff, Carine, Gisonni-Lex, Lucy, Mallet, Laurent, Ng, Siemon H S

“…High-throughput sequencing (HTS) is capable of broad virus detection encompassing both known and unknown adventitious viruses in a variety of sample matrices…”
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Development and application of a salmonid EST database and cDNA microarray: data mining and interspecific hybridization characteristics by Rise, Matthew L, von Schalburg, Kristian R, Brown, Gordon D, Mawer, Melanie A, Devlin, Robert H, Kuipers, Nathanael, Busby, Maura, Beetz-Sargent, Marianne, Alberto, Roberto, Gibbs, A Ross, Hunt, Peter, Shukin, Robert, Zeznik, Jeffrey A, Nelson, Colleen, Jones, Simon R M, Smailus, Duane E, Jones, Steven J M, Schein, Jacqueline E, Marra, Marco A, Butterfield, Yaron S N, Stott, Jeff M, Ng, Siemon H S, Davidson, William S, Koop, Ben F

“…We report 80,388 ESTs from 23 Atlantic salmon (Salmo salar) cDNA libraries (61,819 ESTs), 6 rainbow trout (Oncorhynchus mykiss) cDNA libraries (14,544 ESTs), 2…”
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Advanced Virus Detection Technologies Interest Group (AVDTIG): Efforts on High Throughput Sequencing (HTS) for Virus Detection by Khan, Arifa S, Vacante, Dominick A, Cassart, Jean-Pol, Ng, Siemon H S, Lambert, Christophe, Charlebois, Robert L, King, Kathryn E

“…Several nucleic-acid based technologies have recently emerged with capabilities for broad virus detection. One of these, high throughput sequencing, has the…”
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Erratum: Author Correction: Selection and evaluation of an efficient method for the recovery of viral nucleic acids from complex biologicals by Sathiamoorthy, Sarmitha, Malott, Rebecca J, Gisonni-Lex, Lucy, Ng, Siemon H S

“…[This corrects the article DOI: 10.1038/s41541-018-0067-3.]…”
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Author Correction: Selection and evaluation of an efficient method for the recovery of viral nucleic acids from complex biologicals by Sathiamoorthy, Sarmitha, Malott, Rebecca J., Gisonni-Lex, Lucy, Ng, Siemon H. S.

“…In the original version of this Article the title was incorrectly given as ‘Selection and evaluation of an efficient method for the recovery of viral nucleic…”
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Preliminary Evaluation of Next-Generation Sequencing Performance Relative to qPCR and In Vitro Cell Culture Tests for Human Cytomegalovirus by Ng, Siemon H S, Azizi, Ali, Edamura, Kerrie, Malott, Rebecca J, Charlebois, Robert L, Logvinoff, Carine, Schreiber, Martha, Mallet, Laurent, Gisonni-Lex, Lucy

“…To compare the performances of conventional in vitro indicator cell culture, quantitative polymerase chain reaction (qPCR), and next-generation sequencing…”
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Cataloguing the taxonomic origins of sequences from a heterogeneous sample using phylogenomics: applications in adventitious agent detection by Charlebois, Robert L, Ng, Siemon H S, Gisonni-Lex, Lucy, Mallet, Laurent

“…We have designed and implemented a software system, named PhyloID™, that can be used to detect putative adventitious agents in biological samples characterized…”
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Development of a candidate reference material for adventitious virus detection in vaccine and biologicals manufacturing by deep sequencing by Mee, Edward T, Preston, Mark D, Minor, Philip D, Schepelmann, Silke

“…Highlights • Deep sequencing has potential as an improved adventitious virus screening method. • 15 laboratories sequenced a common reagent containing 25…”
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Trans-Regulation of Mouse Meiotic Recombination Hotspots by Rcr1: e1000036 by Parvanov, Emil D, Ng, Siemon HS, Petkov, Petko M, Paigen, Kenneth

“…Meiotic recombination is required for the orderly segregation of chromosomes during meiosis and for providing genetic diversity among offspring. Among mammals,…”
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The Recombinational Anatomy of a Mouse Chromosome: e1000119 by Paigen, Kenneth, Szatkiewicz, Jin P, Sawyer, Kathryn, Leahy, Nicole, Parvanov, Emil D, Ng, Siemon HS, Graber, Joel H, Broman, Karl W, Petkov, Petko M

“…Among mammals, genetic recombination occurs at highly delimited sites known as recombination hotspots. They are typically 1-2 kb long and vary as much as a…”
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Type I microsatellite markers from Atlantic salmon (Salmo salar) expressed sequence tags by NG, SIEMON H. S., CHANG, ALAN, BROWN, GORDON D., KOOP, BEN F., DAVIDSON, WILLIAM S.

“…The detection of simple sequence repeats (SSRs) within expressed sequence tags (ESTs) connects potential microsatellite markers with specific genes, generating…”
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