Optimal Design and Synthesis of Sustainable Integrated Biorefinery for Pharmaceutical Products from Palm-Based Biomass

Optimal Design and Synthesis of Sustainable Integrated Biorefinery for Pharmaceutical Products from Palm-Based Biomass

In the last decade, numerous technologies have been developed to convert biomass into value-added products (bioenergy, biomaterial and biochemical). However, not much research has been done in the identification of possible pathways to convert biomass into pharmaceutical products. This research focu...

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Bibliographic Details
Published in:Process integration and optimization for sustainability Vol. 1; no. 2; pp. 135 - 151
Main Authors: Ng, Shi Yee, Ong, Sze Ying, Ng, Yee Yin, Liew, Alexander H. B., Ng, Denny K. S., Chemmangattuvalappil, Nishanth G.
Format: Journal Article
Language:English
Published: Singapore Springer Singapore 01-07-2017
Springer Nature B.V
Subjects:
Algae
Alternative energy sources
Biomass
Biomaterials
Biomedical materials
Biorefineries
Carbon sequestration
Chemicals
Cost control
Design optimization
Economics
Economics and Management
Energy Policy
Engineering
Environmental impact
Environmental policy
Fossil fuels
Industrial and Production Engineering
Industrial Chemistry/Chemical Engineering
Lignocellulose
Operating costs
Optimization
Original Research Paper
Pharmaceutical industry
Pharmaceuticals
Raw materials
Refining
Sensitivity analysis
Sustainable Development
Waste Management/Waste Technology
Economic performance
Uncertainty
Integrated biorefinery
Palm-based biomass
Reaction pathway
Pharmaceutical products
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Summary:In the last decade, numerous technologies have been developed to convert biomass into value-added products (bioenergy, biomaterial and biochemical). However, not much research has been done in the identification of possible pathways to convert biomass into pharmaceutical products. This research focuses on exploiting the potential pharmaceutical products that can be derived from palm-based biomass. However, due to the large number of potential products, multiple reaction pathways and processing technologies involved. Thus, there is a need for a systematic methodology which is capable to identify the optimal production routes in the integrated biorefinery based on different optimisation objectives. In this work, a mathematical optimisation-based approach is developed to determine the optimum conversion pathway that converts palm-based biomass into pharmaceutical products with maximum economic performance. Besides, a novel approach which can estimate the operating cost of pharmaceutical products is also introduced in this work. In addition, sensitivity analysis is carried out to investigate the impact of changes in conversion of reaction, market price and operating cost to the economic performance of the synthesised integrated biorefinery.
ISSN:2509-4238
2509-4246
DOI:10.1007/s41660-017-0010-5