Search Results - "Ng, PC"

SIFT: predicting amino acid changes that affect protein function by Ng, Pauline C., Henikoff, Steven

“…Single nucleotide polymorphism (SNP) studies and random mutagenesis projects identify amino acid substitutions in protein-coding regions. Each substitution has…”
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Predicting deleterious amino acid substitutions by Ng, P C, Henikoff, S

“…Many missense substitutions are identified in single nucleotide polymorphism (SNP) data and large-scale random mutagenesis projects. Each amino acid…”
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Accounting for human polymorphisms predicted to affect protein function by Ng, Pauline C, Henikoff, Steven

“…A major interest in human genetics is to determine whether a nonsynonymous single-base nucleotide polymorphism (nsSNP) in a gene affects its protein product…”
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Epidemiological and clinical profiles of acute poisoning in patients admitted to the intensive care unit in eastern Iran (2010 to 2017) by Mehrpour, Omid, Akbari, Ayob, Jahani, Firoozeh, Amirabadizadeh, Alireza, Allahyari, Elaheh, Mansouri, Borhan, Ng, Patrick C

“…Acute poisoning is a common chief complaint leading to emergency department visits and hospital admissions in developing countries such as Iran. Data…”
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Diagnostic markers of infection in neonates by Ng, P C

“…Diagnostic markers of infection are useful indicators of neonatal sepsis. Serial measurements of infection markers can improve diagnostic sensitivity, and the…”
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Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome by Wong, Shell F, Chow, Kam M, Leung, Tse N, Ng, Wai F, Ng, Tak K, Shek, Chi C, Ng, Pak C, Lam, Pansy W.Y, Ho, Lau C, To, William W.K, Lai, Sik T, Yan, Wing W, Tan, Peggy Y.H

“…This study was undertaken to evaluate the pregnancy and perinatal outcomes of pregnant women with severe acute respiratory syndrome (SARS). All pregnant women…”
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Hyperglycemia and adverse pregnancy outcome study: neonatal glycemia by Metzger, Boyd E, Persson, Bengt, Lowe, Lynn P, Dyer, Alan R, Cruickshank, J Kennedy, Deerochanawong, Chaicharn, Halliday, Henry L, Hennis, Anselm J, Liley, Helen, Ng, Pak C, Coustan, Donald R, Hadden, David R, Hod, Moshe, Oats, Jeremy J N, Trimble, Elisabeth R

“…The goal was to describe the temporal pattern of neonatal plasma glucose levels and associations with maternal glucose levels, cord serum C-peptide levels, and…”
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Variations in healthcare worker and parental preferences to surgical management of critically ill preterm infants by Lam, HS, Cheung, HM, Chau, CLS, Ng, PC

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Neonatal mortality in singleton pregnancies: a 20-year retrospective study from a tertiary perinatal unit in Hong Kong by Fung, G P G, Lau, S L, Hui, A S Y, Wong, S T K, Tse, W T, Ng, P C, Sahota, D S, Lam, H S, Leung, T Y

“…The global neonatal death (NND) rate has been declining in recent decades, but there are no comprehensive data concerning the characteristics of NNDs in Hong…”
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Acetaminophen and Acetylsalicylic Acid Exposure in a Preterm Infant after Maternal Overdose by Pavlek, Leeann, Kraft, Monica, Simmons, Caitlyn, Ryan, Mary, Prusakov, Pavel, Campbell, Amanda, Brandehoff, Nicklaus, Ng, Patrick C, Russell, Jason, Ciciora, Steven L, Fathi, Omid

“…Here, we review the case of a 26 1/7 weeks' gestation premature female infant born to a mother who intentionally ingested a large quantity of Tylenol, aspirin,…”
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A Double-Blind, Randomized, Controlled Study of a "Stress Dose" of Hydrocortisone for Rescue Treatment of Refractory Hypotension in Preterm Infants by Ng, Pak C, Lee, Cheuk H, Bnur, Flora Liu, Chan, Iris H.S, Lee, Anthony W.Y, Wong, Eric, Chan, Hin B, Lam, Christopher W.K, Lee, Benjamin S.C, Fok, Tai F

“…To assess the effectiveness of a "stress dose" of hydrocortisone for rescue treatment of refractory hypotension and adrenocortical insufficiency of prematurity…”
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Severe acute respiratory syndrome (SARS) in neonates and children by Li, A M, Ng, P C

“…Severe acute respiratory syndrome (SARS) runs a more benign course in children during the acute phase. Infants born to mothers with the disease did not acquire…”
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Clinical presentations and outcome of severe acute respiratory syndrome in children by Hon, KLE, Leung, CW, Cheng, WTF, Chan, PKS, Chu, WCW, Kwan, YW, Li, AM, Fong, NC, Ng, PC, Chiu, MC, Li, CK, Tam, JS, Fok, TF

“…Hong Kong has been severely affected by severe acute respiratory syndrome (SARS). Contact in households and healthcare settings is thought to be important for…”
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PO-0632 Variations In Healthcare Worker And Parental Preferences To Surgical Management Of Critically Ill Preterm Infants by Lam, HS, Cheung, HM, Chau, CLS, Ng, PC

“…Abstract only…”
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Thrombopoietin protects against in vitro and in vivo cardiotoxicity induced by doxorubicin by KAREN LI, SUNG, Rita Yn Tz, CHI KONG LI, YUEK OI WONG, NG, Pak Cheung, WEI ZHE HUANG, MO YANG, NGA HIN PONG, SHUK MAN LEE, WOOD YEE CHAN, HAILU ZHAO, TO, Man Yin, FOK, Tai Fai

“…Doxorubicin (DOX) is an important antineoplastic agent. However, the associated cardiotoxicity, possibly mediated by the production of reactive oxygen species,…”
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Individual Genomes Instead of Race for Personalized Medicine by Ng, PC, Zhao, Q, Levy, S, Strausberg, RL, Venter, JC

“…The cost of sequencing and genotyping is aggressively decreasing, enabling pervasive personalized genomic screening for drug reactions. Drug‐metabolizing genes…”
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CDLQI, SCORAD and NESS: Are They Correlated? by Hon, K. L. E., Kam, W. Y. C., Lam, M. C. A., Leung, T. F., Ng, P. C.

“…Background: Quality of life (QOL) and clinical severity scores are important parameters in the evaluation of distress experienced by children with atopic…”
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Neutrophil CD64 is a sensitive diagnostic marker for early-onset neonatal infection by NG, Pak C, LI, Geng, CHUI, Kit M, CHU, Winnie C. W, LI, Karen, WONG, Raymond P. O, CHIK, Kai W, WONG, Eric, FOK, Tai F

“…This prospective study aimed to evaluate the diagnostic utilities of neutrophil CD64 expression for the identification of early-onset clinical infection and…”
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Infants Born to Mothers With Severe Acute Respiratory Syndrome by Shek, Chi C, Ng, Pak C, Fung, Genevieve P. G, Cheng, Frankie W. T, Chan, Paul K. S, Peiris, Malik J. S, Lee, Kim H, Wong, Shell F, Cheung, Hon M, Li, Albert M, Hon, Ellis K. L, Yeung, Chung K, Chow, Chun B, Tam, John S, Chiu, Man C, Fok, Tai F

“…Severe acute respiratory syndrome (SARS) is a newly discovered infectious disease caused by a novel coronavirus. During the community outbreak in Hong Kong, 5…”
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Whole-exome sequencing identifies a polymorphism in the BMP5 gene associated with SSRI treatment response in major depression by Tammiste, Anu, Jiang, Tao, Fischer, Krista, Mägi, Reedik, Krjutškov, Kaarel, Pettai, Kristi, Esko, Tõnu, Li, Yingrui, Tansey, Katherine E, Carroll, Liam S, Uher, Rudolf, McGuffin, Peter, Võsa, Urmo, Tšernikova, Natalia, Saria, Alois, Ng, Pauline C, Eller, Triin, Vasar, Veiko, Nutt, David J, Maron, Eduard, Wang, Jun, Metspalu, Andres

“…Although antidepressants are widely used in the pharmacotherapy of major depressive disorder (MDD), their efficacy is still insufficient as approximately…”
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