Search Results - "Ng, P L"

Combining computational and experimental evidence on the activity of antimalarial drugs on papain‐like protease of SARS‐CoV‐2: A repurposing study by Ribaudo, Giovanni, Yun, Xiaoyun, Ongaro, Alberto, Oselladore, Erika, Ng, Jerome P. L., Haynes, Richard K., Law, Betty Yuen Kwan, Memo, Maurizio, Wong, Vincent Kam Wai, Coghi, Paolo, Gianoncelli, Alessandra

“…The development of inhibitors that target the papain‐like protease (PLpro) has the potential to counteract the spread of severe acute respiratory syndrome…”
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Natural Products and Derivatives Targeting Metabolic Reprogramming in Colorectal Cancer: A Comprehensive Review by Wang, Mengyu, Qu, Liqun, Du, Xinying, Song, Peng, Ng, Jerome P L, Wong, Vincent Kam Wai, Law, Betty Yuen Kwan, Fu, Xianjun

“…Metabolic reprogramming is a critical pathogenesis of colorectal cancer (CRC), referring to metabolic disorders that cancer cells make in response to the…”
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Dysregulation of miR-31 and miR-375 expression is associated with clinical outcomes in oral carcinoma by Siow, MY, Karen Ng, LP, Vincent Chong, VK, Jamaludin, M, Abraham, MT, Abdul Rahman, ZA, Kallarakkal, TG, Yang, Y-H, Cheong, SC, Zain, RB

“…Objectives To identify differentially expressed miRNA between oral squamous cell carcinoma (OSCC) and non‐cancer (NC) and to associate these with…”
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Heterogenous antibody and T‐cell responses to SARS‐CoV‐2 mRNA vaccines among immunocompromised young people by Lu, Liangjian, Chan, Chang Yien, Chan‐Ng, Pauline P. L., Than, Mya, Tan, Pamela S. Y., Lim, Lee Kean, Teo, Sharon, Lau, Perry YW, Ng, Kar Hui, Ang, Elizabeth Y., Karthik, Sivaramakrishnan Venkatesh, Aw, Marion M., Tambyah, Paul A., Yap, Hui Kim, Lee, Bee Wah

“…Baseline characteristics (Table 1, Figure 1A) were comparable between controls and the immunocompromised cohort, and disease groups were homogenous in terms of…”
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Acropetal Auxin Transport Inhibition Is Involved in Indeterminate But Not Determinate Nodule Formation by Ng, Jason L P, Mathesius, Ulrike

“…Legumes enter into a symbiotic relationship with nitrogen-fixing rhizobia, leading to nodule development. Two main types of nodules have been widely studied,…”
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Structural Modification of Epigallocatechin-3-gallate to (2R,3R)-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)chroman-3-yl l-valinate in Four Steps by Yu, Xiaoman, Ren, Zimo, Coghi, Paolo, Ng, Jerome P. L.

“…Tea is a daily drink for most people, and one of its major ingredients, epigallocatechin-3-gallate (EGCG), has been widely recognized as a potent antioxidant…”
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A Drug Repurposing Approach for Antimalarials Interfering with SARS-CoV-2 Spike Protein Receptor Binding Domain (RBD) and Human Angiotensin-Converting Enzyme 2 (ACE2) by Coghi, Paolo, Yang, Li Jun, Ng, Jerome P L, Haynes, Richard K, Memo, Maurizio, Gianoncelli, Alessandra, Wong, Vincent Kam Wai, Ribaudo, Giovanni

“…Host cell invasion by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is mediated by the interaction of the viral spike protein (S) with human…”
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Establishing and managing a periodontal biobank for research: the sharing of experience by Vaithilingam, RD, Safii, SH, Baharuddin, NA, Karen-Ng, LP, Saub, R, Ariffin, F, Ramli, H, Sharifuddin, A, Hidayat, MFH, Raman, R, Chan, YK, Rani, NA, Rahim, RA, Shahruddin, N, Cheong, SC, Bartold, PM, Zain, RB

“…Periodontal bio‐repositories, which allow banking of clinically validated human data and biological samples, provide an opportunity to derive biomarkers for…”
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Antimalarial and antitumour activities of the steroidal quinone-methide celastrol and its combinations with artemiside, artemisone and methylene blue by Ng, Jerome P. L., Han, Yu, Yang, Li Jun, Birkholtz, Lyn-Marie, Coertzen, Dina, Wong, Ho Ning, Haynes, Richard K., Coghi, Paolo, Wong, Vincent Kam Wai

“…Artemisinin, isolated from the traditional Chinese medicinal plant qīng hāo 青蒿 ( Artemisia annua ) and its derivatives are used for treatment of malaria. With…”
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Biological Evaluation in Resistant Cancer Cells and Study of Mechanism of Action of Arylvinyl-1,2,4-Trioxanes by Ng, Jerome P L, Tiwari, Mohit K, Nasim, Ali Adnan, Zhang, Rui Long, Qu, Yuanqing, Sharma, Richa, Law, Betty Yuen Kwan, Yadav, Dharmendra K, Chaudhary, Sandeep, Coghi, Paolo, Wong, Vincent Kam Wai

“…1,2,4-trioxane is a pharmacophore, which possesses a wide spectrum of biological activities, including anticancer effects. In this study, the cytotoxic effect…”
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Accumulation of and Response to Auxins in Roots and Nodules of the Actinorhizal Plant Datisca glomerata Compared to the Model Legume Medicago truncatula by Demina, Irina V., Maity, Pooja Jha, Nagchowdhury, Anurupa, Ng, Jason L. P., van der Graaff, Eric, Demchenko, Kirill N., Roitsch, Thomas, Mathesius, Ulrike, Pawlowski, Katharina

“…Actinorhizal nodules are structurally different from legume nodules and show a greater similarity to lateral roots. Because of the important role of auxins in…”
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Mutant p53R211 ameliorates inflammatory arthritis in AIA rats via inhibition of TBK1-IRF3 innate immune response by Zeng, Yaling, Ng, Jerome P. L., Wang, Linna, Xu, Xiongfei, Law, Betty Yuen Kwan, Chen, Guobing, Lo, Hang Hong, Yang, Lijun, Yang, Jiujie, Zhang, Lei, Qu, Liqun, Yun, Xiaoyun, Zhong, Jing, Chen, Ruihong, Zhang, Dingqi, Wang, Yuping, Luo, Weidan, Qiu, Congling, Huang, Baixiong, liu, Wenfeng, Liu, Liang, Wong, Vincent Kam Wai

“…Background Rheumatoid arthritis (RA) is an autoimmune inflammation disease characterized by imbalance of immune homeostasis. p53 mutants are commonly described…”
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Synthesis and Coordination Properties of a Water-Soluble Material by Cross-Linking Low Molecular Weight Polyethyleneimine with Armed Cyclotriveratrilene by Ng, Yoke Mooi, Coghi, Paolo, Ng, Jerome P L, Ali, Fayaz, Wong, Vincent Kam Wai, Coluccini, Carmine

“…In this study, a full organic and water-soluble material was synthesized by coupling low molecular weight polyethylenimine (PEI-800) with cyclotriveratrilene…”
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Seropositivity of HPV 16 E6 and E7 and the risk of oral cancer by Wong, GR, Ha, KO, Himratul-Aznita, WH, Yang, YH, Wan Mustafa, WM, Yuen, KM, Abraham, MT, Tay, KK, Karen-Ng, LP, Cheong, SC, Zain, RB

“…Objectives The objective of the study was to determine the prevalence of HPV seropositivity among patients with oral squamous cell carcinoma (OSCC) and healthy…”
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Neurocysticercosis in a young Indian male by Ng, E Pl, Woo, P Ym, Wong, A Ks, Chan, K Y

“…Images of the patient(a) Computed tomography demonstrating an intra-axial right parietal lesion with a calcific focus (axial, white arrow). (b) Hole-with-dot…”
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Roles of packing density and slurry film thickness in synergistic effects of metakaolin and silica fume by Chu, S.H., Chen, J.J., Li, L.G., Ng, P.L., Kwan, A.K.H.

“…Metakaolin (MK) and silica fume (SF) have been added either individually or in combination to improve concrete performance. Recent studies proved that the…”
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N-[7-Chloro-4-[4-(phenoxymethyl)-1H-1,2,3-triazol-1-yl]quinoline]-acetamide by Coghi, Paolo, Ng, Jerome P. L., Nasim, Ali Adnan, Wong, Vincent Kam Wai

“…The 1,2,3-triazole is a well-known biologically active pharmacophore constructed by the copper-catalyzed azide–alkyne cycloaddition. We herein reported the…”
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An 11-year review of dermatomyositis in Asian patients by Liu, Wen Chun, Ho, Madeline, Koh, Woon-Puay, Tan, Audrey W H, Ng, Patricia P L, Chua, Sze Hon, Tan, Suat Hoon, Tang, Mark B Y

“…Dermatomyositis (DM) is a multisystem inflammatory disease with a strong association with malignancy. We aimed to describe a series of Asian patients with DM…”
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Genome-wide analysis of oral squamous cell carcinomas revealed over expression of ISG15, Nestin and WNT11 by Vincent-Chong, VK, Ismail, SM, Rahman, ZAA, Sharifah, NA, Anwar, A, Pradeep, PJ, Ramanathan, A, Karen-Ng, LP, Kallarakkal, TG, Mustafa, WMW, Abraham, MT, Tay, KK, Zain, RB

“…Oral Diseases (2012) 18, 469–476 Background:  Multistep pathways and mechanisms are involved in the development of oral cancer. Chromosomal alterations are one…”
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Optimum Fines Content in Manufactured Sand for Best Overall Performance of Superplasticized Concrete by Chen, J. J., Ng, P. L., Kwan, A. K. H.

“…Due to a shortage of river sand for concrete production, manufactured sand (MS) made from crushed rock has gradually become a substitute. It inherently…”
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