Search Results - "Ng, Maggie"

Association of kidney structure-related gene variants with type 2 diabetes-attributed end-stage kidney disease in African Americans by Guan, Meijian, Ma, Jun, Keaton, Jacob M., Dimitrov, Latchezar, Mudgal, Poorva, Stromberg, Mary, Bonomo, Jason A., Hicks, Pamela J., Freedman, Barry I., Bowden, Donald W., Ng, Maggie C. Y.

“…African Americans (AAs) are at higher risk for developing end-stage kidney disease (ESKD) compared to European Americans. Genome-wide association studies have…”
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Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus by Kasuga, Masato, Yasuda, Kazuki, Miyake, Kazuaki, Horikawa, Yukio, Hara, Kazuo, Osawa, Haruhiko, Furuta, Hiroto, Hirota, Yushi, Mori, Hiroyuki, Jonsson, Anna, Sato, Yoshifumi, Yamagata, Kazuya, Hinokio, Yoshinori, Wang, He-Yao, Tanahashi, Toshihito, Nakamura, Naoto, Oka, Yoshitomo, Iwasaki, Naoko, Iwamoto, Yasuhiko, Yamada, Yuichiro, Seino, Yutaka, Maegawa, Hiroshi, Kashiwagi, Atsunori, Takeda, Jun, Maeda, Eiichi, Shin, Hyoung Doo, Cho, Young Min, Park, Kyong Soo, Lee, Hong Kyu, Ng, Maggie C Y, Ma, Ronald C W, So, Wing-Yee, Chan, Juliana C N, Lyssenko, Valeriya, Tuomi, Tiinamaija, Nilsson, Peter, Groop, Leif, Kamatani, Naoyuki, Sekine, Akihiro, Nakamura, Yusuke, Yamamoto, Ken, Yoshida, Teruhiko, Tokunaga, Katsushi, Itakura, Mitsuo, Makino, Hideichi, Nanjo, Kishio, Kadowaki, Takashi

“…We carried out a multistage genome-wide association study of type 2 diabetes mellitus in Japanese individuals, with a total of 1,612 cases and 1,424 controls…”
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Identification of type 2 diabetes loci in 433,540 East Asian individuals by Spracklen, Cassandra N., Horikoshi, Momoko, Kim, Young Jin, Lin, Kuang, Moon, Sanghoon, Suzuki, Ken, Tam, Claudia H. T., Tabara, Yasuharu, Kwak, Soo-Heon, Takeuchi, Fumihiko, Long, Jirong, Lim, Victor J. Y., Chai, Jin-Fang, Chen, Chien-Hsiun, Nakatochi, Masahiro, Yao, Jie, Choi, Hyeok Sun, Iyengar, Apoorva K., Perrin, Hannah J., Brotman, Sarah M., van de Bunt, Martijn, Gloyn, Anna L., Below, Jennifer E., Boehnke, Michael, Chambers, John C., Mahajan, Anubha, McCarthy, Mark I., Ng, Maggie C. Y., Petty, Lauren E., Zhang, Weihua, Morris, Andrew P., Adair, Linda S., Akiyama, Masato, Bian, Zheng, Chan, Juliana C. N., Chang, Li-Ching, Chee, Miao-Li, Chen, Yii-Der Ida, Chen, Yuan-Tsong, Chen, Zhengming, Chuang, Lee-Ming, Du, Shufa, Gordon-Larsen, Penny, Gross, Myron, Guo, Xiuqing, Guo, Yu, Han, Sohee, Howard, Annie-Green, Huang, Wei, Hung, Yi-Jen, Hwang, Mi Yeong, Hwu, Chii-Min, Isono, Masato, Jang, Hye-Mi, Jiang, Guozhi, Kamatani, Yoichiro, Katsuya, Tomohiro, Kawaguchi, Takahisa, Lee, Myung-Shik, Lee, Nanette R., Li, Liming, Liu, Jianjun, Luk, Andrea O., Pereira, Mark A., Sabanayagam, Charumathi, Shi, Jinxiu, Shin, Dong Mun, So, Wing Yee, Takahashi, Atsushi, Tomlinson, Brian, van Dam, Rob M., Xiang, Yong-Bing, Yamamoto, Ken, Yamauchi, Toshimasa, Yoon, Kyungheon, Yu, Canqing, Yuan, Jian-Min, Zhang, Liang, Zheng, Wei, Igase, Michiya, Cho, Yoon Shin, Rotter, Jerome I., Wang, Ya-Xing, Sheu, Wayne H. H., Yokota, Mitsuhiro, Wu, Jer-Yuarn, Cheng, Ching-Yu, Shu, Xiao-Ou, Kato, Norihiro, Park, Kyong-Soo, Tai, E-Shyong, Matsuda, Fumihiko, Koh, Woon-Puay, Ma, Ronald C. W., Millwood, Iona Y., Lee, Juyoung, Walters, Robin G., Kim, Bong-Jo, Mohlke, Karen L., Sim, Xueling

“…Meta-analyses of genome-wide association studies (GWAS) have identified more than 240 loci that are associated with type 2 diabetes (T2D) 1 , 2 ; however, most…”
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Evaluation of candidate nephropathy susceptibility genes in a genome-wide association study of African American diabetic kidney disease by Palmer, Nicholette D, Ng, Maggie C Y, Hicks, Pamela J, Mudgal, Poorva, Langefeld, Carl D, Freedman, Barry I, Bowden, Donald W

“…Type 2 diabetes (T2D)-associated end-stage kidney disease (ESKD) is a complex disorder resulting from the combined influence of genetic and environmental…”
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Implication of Genetic Variants Near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in Type 2 Diabetes and Obesity in 6,719 Asians by Ng, Maggie C Y, Park, Kyong Soo, Oh, Bermseok, Tam, Claudia H T, Cho, Young Min, Shin, Hyoung Doo, Lam, Vincent K L, Ma, Ronald C W, So, Wing Yee, Cho, Yoon Shin, Kim, Hyung-Lae, Lee, Hong Kyu, Chan, Juliana C N, Cho, Nam H

“…Implication of Genetic Variants Near TCF7L2 , SLC30A8 , HHEX , CDKAL1 , CDKN2A/B , IGF2BP2 , and FTO in Type 2 Diabetes and Obesity in 6,719 Asians Maggie C.Y…”
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Genetics of Type 2 Diabetes in U.S. Hispanic/Latino Individuals: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) by Qi, Qibin, Stilp, Adrienne M, Sofer, Tamar, Moon, Jee-Young, Hidalgo, Bertha, Szpiro, Adam A, Wang, Tao, Ng, Maggie C Y, Guo, Xiuqing, Chen, Yii-Der Ida, Taylor, Kent D, Aviles-Santa, M Larissa, Papanicolaou, George, Pankow, James S, Schneiderman, Neil, Laurie, Cathy C, Rotter, Jerome I, Kaplan, Robert C

“…Few genome-wide association studies (GWAS) of type 2 diabetes (T2D) have been conducted in U.S. Hispanics/Latinos of diverse backgrounds who are…”
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A comparison of type 2 diabetes risk allele load between African Americans and European Americans by Keaton, Jacob M., Cooke Bailey, Jessica N., Palmer, Nicholette D., Freedman, Barry I., Langefeld, Carl D., Ng, Maggie C. Y., Bowden, Donald W.

“…The prevalence of type 2 diabetes (T2D) is greater in populations of African descent compared to European-descent populations. Genetic risk factors may…”
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Polygenic Risk for Type 2 Diabetes in African Americans by Irvin, Marguerite R, Ge, Tian, Patki, Amit, Srinivasasainagendra, Vinodh, Armstrong, Nicole D, Davis, Brittney, Jones, Alana C, Perez, Emma, Stalbow, Lauren, Lebo, Matthew, Kenny, Eimear, Loos, Ruth J F, Ng, Maggie C Y, Smoller, Jordan W, Meigs, James B, Lange, Leslie A, Karlson, Elizabeth W, Limdi, Nita A, Tiwari, Hemant K

“…African Americans (AAs) have been underrepresented in polygenic risk score (PRS) studies. Here, we integrated genome-wide data from multiple observational…”
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Mapping adipose and muscle tissue expression quantitative trait loci in African Americans to identify genes for type 2 diabetes and obesity by Sajuthi, Satria P., Sharma, Neeraj K., Chou, Jeff W., Palmer, Nicholette D., McWilliams, David R., Beal, John, Comeau, Mary E., Ma, Lijun, Calles-Escandon, Jorge, Demons, Jamehl, Rogers, Samantha, Cherry, Kristina, Menon, Lata, Kouba, Ethel, Davis, Donna, Burris, Marcie, Byerly, Sara J., Ng, Maggie C. Y., Maruthur, Nisa M., Patel, Sanjay R., Bielak, Lawrence F., Lange, Leslie A., Guo, Xiuqing, Sale, Michèle M., Chan, Kei Hang K., Monda, Keri L., Chen, Gary K., Taylor, Kira, Palmer, Cameron, Edwards, Todd L., North, Kari E., Haiman, Christopher A., Bowden, Donald W., Freedman, Barry I., Langefeld, Carl D., Das, Swapan K.

“…Relative to European Americans, type 2 diabetes (T2D) is more prevalent in African Americans (AAs). Genetic variation may modulate transcript abundance in…”
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Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study by Wing, Maria R, Ziegler, Julie, Langefeld, Carl D, Ng, Maggie C. Y, Haffner, Steven M, Norris, Jill M, Goodarzi, Mark O, Bowden, Donald W

“…Multiple studies have identified FTO gene variants associated with measures of adiposity in European-derived populations. The objective of the study was to…”
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Photocontrolled multiple-state photochromic benzo[b]phosphole thieno[3,2-b]phosphole-containing alkynylgold(I) complex via selective light irradiation by Wu, Nathan Man-Wai, Ng, Maggie, Yam, Vivian Wing-Wah

“…Photochromic materials have drawn growing attention because using light as a stimulus has been regarded as a convenient and environmental-friendly way to…”
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Integrated multi‐omic analyses uncover the effects of aging on cell‐type regulation in glucose‐responsive tissues by Xu, Peng, Kong, Yimeng, Palmer, Nicholette D., Ng, Maggie C. Y., Zhang, Bin, Das, Swapan K.

“…Aging significantly influences cellular activity and metabolism in glucose‐responsive tissues, yet a comprehensive evaluation of the impacts of aging and…”
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Genetic Risk Score Associations With Cardiovascular Disease and Mortality in the Diabetes Heart Study by COX, Amanda J, HSU, Fang-Chi, NG, Maggie C. Y, LANGEFELD, Carl D, FREEDMAN, Barry I, CARR, J. Jeffrey, BOWDEN, Donald W

“…OBJECTIVE Given the high rates of cardiovascular disease (CVD) and associated mortality in individuals with type 2 diabetes, identifying and understanding…”
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Resequencing and Analysis of Variation in the TCF7L2 Gene in African Americans Suggests That SNP rs7903146 Is the Causal Diabetes Susceptibility Variant by PALMER, Nicholette D, HESTER, Jessica M, SANDY AN, S, ADEYEMO, Adebowale, ROTIMI, Charles, LANGEFELD, Carl D, FREEDMAN, Barry I, NG, Maggie C. Y, BOWDEN, Donald W

“…Variation in the transcription factor 7-like 2 (TCF7L2) locus is associated with type 2 diabetes across multiple ethnicities. The aim of this study was to…”
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Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions by Langefeld, Carl D, Comeau, Mary E, Ng, Maggie C Y, Guan, Meijian, Dimitrov, Latchezar, Mudgal, Poorva, Spainhour, Mitzie H, Julian, Bruce A, Edberg, Jeffrey C, Croker, Jennifer A, Divers, Jasmin, Hicks, Pamela J, Bowden, Donald W, Chan, Gary C, Ma, Lijun, Palmer, Nicholette D, Kimberly, Robert P, Freedman, Barry I

“…African Americans carrying two apolipoprotein L1 gene (APOL1) renal risk variants have a high risk for nephropathy. However, only a minority develops end-stage…”
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Genetic Risk Assessment of Type 2 Diabetes-Associated Polymorphisms in African Americans by COOKE, Jessica N, NG, Maggie C. Y, PALMER, Nicholette D, SANDY AN, S, HESTER, Jessica M, FREEDMAN, Barry I, LANGEFELD, Carl D, BOWDEN, Donald W

“…Multiple single nucleotide polymorphisms (SNPs) associated with type 2 diabetes (T2D) susceptibility have been identified in predominantly European-derived…”
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Strategies towards rational design of gold(iii) complexes for high-performance organic light-emitting devices by Li, Lok-Kwan, Tang, Man-Chung, Lai, Shiu-Lun, Ng, Maggie, Kwok, Wing-Kei, Chan, Mei-Yee, Yam, Vivian Wing-Wah

“…Gold( iii ) complexes are attractive candidates as phosphorescent dopants in organic light-emitting devices for high-luminance full-colour displays. However,…”
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Genetics of Type 2 Diabetes in African Americans by Ng, Maggie C. Y.

“…Type 2 diabetes (T2D) is a global health problem showing substantial ethnic disparity in disease prevalence. African Americans have one of the highest…”
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Genome-wide association study of vitamin D concentrations and bone mineral density in the African American-Diabetes Heart Study by Palmer, Nicholette D, Lu, Lingyi, Register, Thomas C, Lenchik, Leon, Carr, J Jeffrey, Hicks, Pamela J, Smith, S Carrie, Xu, Jianzhao, Dimitrov, Latchezar, Keaton, Jacob, Guan, Meijian, Ng, Maggie C Y, Chen, Yii-der I, Hanley, Anthony J, Engelman, Corinne D, Norris, Jill M, Langefeld, Carl D, Wagenknecht, Lynne E, Bowden, Donald W, Freedman, Barry I, Divers, Jasmin

“…Relative to European Americans, African Americans have lower 25-hydroxyvitamin D (25OHD) and vitamin D binding protein (VDBP) concentrations, higher…”
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Identification of Type 2 Diabetes Genes in Mexican Americans Through Genome-Wide Association Studies by Hayes, M Geoffrey, Pluzhnikov, Anna, Miyake, Kazuaki, Sun, Ying, Ng, Maggie C Y, Roe, Cheryl A, Below, Jennifer E, Nicolae, Raluca I, Konkashbaev, Anuar, Bell, Graeme I, Cox, Nancy J, Hanis, Craig L

“…Identification of Type 2 Diabetes Genes in Mexican Americans Through Genome-Wide Association Studies M. Geoffrey Hayes 1 , Anna Pluzhnikov 1 , Kazuaki Miyake 1…”
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