Search Results - "Ng, Kah Ying"
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Variant-Specific IgA Protects Against Omicron Infection
Published in The Journal of infectious diseases (16-08-2024)“…Abstract Background The emergence of rapidly evolving severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, coupled with waning…”
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Clinical evaluation of a low cost, in-house developed real-time RT-PCR human immunodeficiency virus type 1 (HIV-1) quantitation assay for HIV-1 infected patients
Published in PloS one (06-03-2014)“…HIV-1 viral quantitation is essential for treatment monitoring. An in-house assay would decrease financial barriers to access. A real-time competitive RT-PCR…”
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3
HIV-1 Transmission Networks Among Men Who Have Sex With Men in Asia
Published in Clinical infectious diseases (15-09-2014)Get full text
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4
High prevalence of CXCR4 usage among treatment-naive CRF01_AE and CRF51_01B-infected HIV-1 subjects in Singapore
Published in BMC infectious diseases (19-02-2013)“…Recent studies suggest HIV-1 inter-subtype differences in co-receptor usage. We examined the correlation between HIV-1 subtype and co-receptor usage among…”
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Phylodynamic profile of HIV-1 subtype B, CRF01_AE and the recently emerging CRF51_01B among men who have sex with men (MSM) in Singapore
Published in PloS one (02-12-2013)“…HIV-1 subtype B and CRF01_AE are the predominant infecting subtypes among men who have sex with men (MSM) in Singapore. The genetic history, population…”
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6
Detection and genetic characterisation of qnrB in hospital isolates of Klebsiella pneumoniae in Singapore
Published in International journal of antimicrobial agents (01-02-2009)“…Abstract Polymerase chain reaction (PCR) screening of 116 ciprofloxacin-resistant Klebsiella pneumoniae hospital isolates for the presence of qnr genes that…”
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Sucrose Gradient Analysis of Human Mitochondrial Ribosomes and RNA
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…Faithful expression of the mitochondrial genome is required for the synthesis of the oxidative phosphorylation complexes and cell fitness. In humans,…”
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Translation of MT-ATP6 pathogenic variants reveals distinct regulatory consequences from the co-translational quality control of mitochondrial protein synthesis
Published in Human molecular genetics (22-04-2022)“…Abstract Pathogenic variants that disrupt human mitochondrial protein synthesis are associated with a clinically heterogeneous group of diseases. Despite an…”
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Bi-allelic variants in the mitochondrial RNase P subunit PRORP cause mitochondrial tRNA processing defects and pleiotropic multisystem presentations
Published in American journal of human genetics (04-11-2021)“…Human mitochondrial RNase P (mt-RNase P) is responsible for 5′ end processing of mitochondrial precursor tRNAs, a vital step in mitochondrial RNA maturation,…”
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10
Nonstop mRNAs generate a ground state of mitochondrial gene expression noise
Published in Science advances (16-11-2022)“…A stop codon within the mRNA facilitates coordinated termination of protein synthesis, releasing the nascent polypeptide from the ribosome. This essential step…”
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Mitochondrial stress response triggered by defects in protein synthesis quality control
Published in Life science alliance (01-02-2019)“…Mitochondria have a compartmentalized gene expression system dedicated to the synthesis of membrane proteins essential for oxidative phosphorylation…”
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Clinical Evaluation of a Low Cost, In-House Developed Real-Time RT-PCR Human Immunodeficiency Virus Type 1
Published in PloS one (06-03-2014)“…Objectives HIV-1 viral quantitation is essential for treatment monitoring. An in-house assay would decrease financial barriers to access. Materials and Methods…”
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13
Phylodynamic Profile of HIV-1 Subtype B, CRF01_AE and the Recently Emerging CRF51_01B among Men Who Have Sex with Men
Published in PloS one (02-12-2013)“…HIV-1 subtype B and CRF01_AE are the predominant infecting subtypes among men who have sex with men (MSM) in Singapore. The genetic history, population…”
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14
Clinical evaluation of an in-house human immunodeficiency virus (HIV) genotyping assay for the detection of drug resistance mutations in HIV-1 infected patients in Singapore
Published in Annals of the Academy of Medicine, Singapore (01-12-2012)“…Human immunodeficiency virus type 1 (HIV-1) genotyping resistance test (GRT) is essential for monitoring HIV-1 drug resistance mutations (DRMs). High cost and…”
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Clinical Evaluation of a Low Cost, In-House Developed Real-Time RT-PCR Human Immunodeficiency Virus Type 1 (HIV-1) Quantitation Assay for HIV-1 Infected Patients: e89826
Published in PloS one (01-03-2014)“…Objectives HIV-1 viral quantitation is essential for treatment monitoring. An in-house assay would decrease financial barriers to access. Materials and Methods…”
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Journal Article -
16
Phylodynamic Profile of HIV-1 Subtype B, CRF01ULAE and the Recently Emerging CRF51UL01B among Men Who Have Sex with Men (MSM) in Singapore: e80884
Published in PloS one (01-12-2013)“…HIV-1 subtype B and CRF01ULAE are the predominant infecting subtypes among men who have sex with men (MSM) in Singapore. The genetic history, population…”
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