Search Results - "Ng, Elizabeth"

Human haematopoietic stem cell development: from the embryo to the dish by Ivanovs, Andrejs, Rybtsov, Stanislav, Ng, Elizabeth S, Stanley, Edouard G, Elefanty, Andrew G, Medvinsky, Alexander

“…Haematopoietic stem cells (HSCs) emerge during embryogenesis and give rise to the adult haematopoietic system. Understanding how early haematopoietic…”
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Mapping human haematopoietic stem cells from haemogenic endothelium to birth by Calvanese, Vincenzo, Capellera-Garcia, Sandra, Ma, Feiyang, Fares, Iman, Liebscher, Simone, Ng, Elizabeth S., Ekstrand, Sophia, Aguadé-Gorgorió, Júlia, Vavilina, Anastasia, Lefaudeux, Diane, Nadel, Brian, Li, Jacky Y., Wang, Yanling, Lee, Lydia K., Ardehali, Reza, Iruela-Arispe, M. Luisa, Pellegrini, Matteo, Stanley, Ed G., Elefanty, Andrew G., Schenke-Layland, Katja, Mikkola, Hanna K. A.

“…The ontogeny of human haematopoietic stem cells (HSCs) is poorly defined owing to the inability to identify HSCs as they emerge and mature at different…”
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Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells to Cardiomyocytes: A Methods Overview by Mummery, Christine L, Zhang, Jianhua, Ng, Elizabeth S, Elliott, David A, Elefanty, Andrew G, Kamp, Timothy J

“…Since human embryonic stem cells were first differentiated to beating cardiomyocytes a decade ago, interest in their potential applications has increased…”
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Rapid training of healthcare staff for protected cardiopulmonary resuscitation in the COVID-19 pandemic by Foong, Theng W, Hui Ng, Elizabeth S, Wee Khoo, Cicely Y, Ashokka, Balakrishnan, Khoo, Deborah, Agrawal, Rohit

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Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages by Ditadi, Andrea, Sturgeon, Christopher M., Tober, Joanna, Awong, Geneve, Kennedy, Marion, Yzaguirre, Amanda D., Azzola, Lisa, Ng, Elizabeth S., Stanley, Edouard G., French, Deborah L., Cheng, Xin, Gadue, Paul, Speck, Nancy A., Elefanty, Andrew G., Keller, Gordon

“…The generation of haematopoietic stem cells (HSCs) from human pluripotent stem cells (hPSCs) will depend on the accurate recapitulation of embryonic…”
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Lymphoid cell development from fetal hematopoietic progenitors and human pluripotent stem cells by Sun, Shicheng, Wijanarko, Kevin, Liani, Oniko, Strumila, Kathleen, Ng, Elizabeth S., Elefanty, Andrew G., Stanley, Edouard G.

“…Summary Lymphoid cells encompass the adaptive immune system, including T and B cells and Natural killer T cells (NKT), and innate immune cells (ILCs),…”
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Effects of yogurt starter cultures on the survival of Lactobacillus acidophilus by Ng, Elizabeth W., Yeung, Marie, Tong, Phillip S.

“…Recognized to confer health benefits to consumers, probiotics such as Lactobacillus acidophilus are commonly incorporated into fermented dairy products…”
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A protocol describing the use of a recombinant protein-based, animal product-free medium (APEL) for human embryonic stem cell differentiation as spin embryoid bodies by Elefanty, Andrew G, Ng, Elizabeth S, Davis, Richard, Stanley, Edouard G

“…In order to promote the uniform and reproducible differentiation of human embryonic stem cells (HESCs) in response to exogenously added growth factors, we have…”
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Discovery of Covalent Inhibitors Targeting the Transcriptional Enhanced Associate Domain Central Pocket by Karatas, Hacer, Akbarzadeh, Mohammad, Adihou, Hélène, Hahne, Gernot, Pobbati, Ajaybabu V, Yihui Ng, Elizabeth, Guéret, Stéphanie M, Sievers, Sonja, Pahl, Axel, Metz, Malte, Zinken, Sarah, Dötsch, Lara, Nowak, Christine, Thavam, Sasikala, Friese, Alexandra, Kang, CongBao, Hong, Wanjin, Waldmann, Herbert

“…Transcriptional enhanced associate domain (TEAD) transcription factors together with coactivators and corepressors modulate the expression of genes that…”
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Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros by Ng, Elizabeth S, Azzola, Lisa, Bruveris, Freya F, Calvanese, Vincenzo, Phipson, Belinda, Vlahos, Katerina, Hirst, Claire, Jokubaitis, Vanta J, Yu, Qing C, Maksimovic, Jovana, Liebscher, Simone, Januar, Vania, Zhang, Zhen, Williams, Brenda, Conscience, Aude, Durnall, Jennifer, Jackson, Steven, Costa, Magdaline, Elliott, David, Haylock, David N, Nilsson, Susan K, Saffery, Richard, Schenke-Layland, Katja, Oshlack, Alicia, Mikkola, Hanna K A, Stanley, Edouard G, Elefanty, Andrew G

“…Human embryonic stem cells are differentiated to cells similar to the embryonic aorta-gonad-mesonephros, which gives rise to hematopoietic stem cells. The…”
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VEGF, FGF2, and BMP4 regulate transitions of mesoderm to endothelium and blood cells in a human model of yolk sac hematopoiesis by Bruveris, Freya F., Ng, Elizabeth S., Stanley, Edouard G., Elefanty, Andrew G.

“…•Methylcellulose blast colony assay mimics yolk sac hematopoiesis.•FGF2 and VEGF are critical signals for the progression of mesoderm into endothelium.•BMP4 is…”
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Expression of RUNX1-ETO Rapidly Alters the Chromatin Landscape and Growth of Early Human Myeloid Precursor Cells by Nafria, Monica, Keane, Peter, Ng, Elizabeth S., Stanley, Edouard G., Elefanty, Andrew G., Bonifer, Constanze

“…Acute myeloid leukemia (AML) is a hematopoietic malignancy caused by recurrent mutations in genes encoding transcriptional, chromatin, and/or signaling…”
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Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids by Motazedian, Ali, Bruveris, Freya F., Kumar, Santhosh V., Schiesser, Jacqueline V., Chen, Tyrone, Ng, Elizabeth S., Chidgey, Ann P., Wells, Christine A., Elefanty, Andrew G., Stanley, Edouard G.

“…Defining the ontogeny of the human adaptive immune system during embryogenesis has implications for understanding childhood diseases including leukaemias and…”
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Efficient generation of human NOTCH ligand-expressing haemogenic endothelial cells as infrastructure for in vitro haematopoiesis and lymphopoiesis by Sun, Shicheng, Motazedian, Ali, Li, Jacky Y., Wijanarko, Kevin, Zhu, Joe Jiang, Tharmarajah, Kothila, Strumila, Kathleen A., Shkaruta, Anton, Nigos, L. Rayburn, Schiesser, Jacqueline V., Yu, Yi, Neeson, Paul J., Ng, Elizabeth S., Elefanty, Andrew G., Stanley, Edouard G.

“…Arterial endothelial cells (AECs) are the founder cells for intraembryonic haematopoiesis. Here, we report a method for the efficient generation of human…”
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Modeling human skeletal development using human pluripotent stem cells by Lamandé, Shireen R, Ng, Elizabeth S, Cameron, Trevor L, Kung, Louise H W, Sampurno, Lisa, Rowley, Lynn, Lilianty, Jinia, Patria, Yudha Nur, Stenta, Tayla, Hanssen, Eric, Bell, Katrina M, Saxena, Ritika, Stok, Kathryn S, Stanley, Edouard G, Elefanty, Andrew G, Bateman, John F

“…Chondrocytes and osteoblasts differentiated from induced pluripotent stem cells (iPSCs) will provide insights into skeletal development and genetic skeletal…”
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Predator stomach contents can provide accurate indices of prey biomass by Ng, Elizabeth L, Deroba, Jonathan J, Essington, Timothy E, Grüss, Arnaud, Smith, Brian E, Thorson, James T

“…Abstract Diet-based annual biomass indices can potentially use predator stomach contents to provide information about prey biomass and may be particularly…”
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NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes by Elliott, David A, Braam, Stefan R, Koutsis, Katerina, Ng, Elizabeth S, Jenny, Robert, Lagerqvist, Ebba L, Biben, Christine, Hatzistavrou, Tanya, Hirst, Claire E, Yu, Qing C, Skelton, Rhys J P, Ward-van Oostwaard, Dorien, Lim, Sue Mei, Khammy, Ouda, Li, Xueling, Hawes, Susan M, Davis, Richard P, Goulburn, Adam L, Passier, Robert, Prall, Owen W J, Haynes, John M, Pouton, Colin W, Kaye, David M, Mummery, Christine L, Elefanty, Andrew G, Stanley, Edouard G

“…NKX2-5 is expressed in the heart throughout life. We targeted eGFP sequences to the NKX2-5 locus of human embryonic stem cells (hESCs); NKX2-5(eGFP/w) hESCs…”
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Long-term engrafting multilineage hematopoietic cells differentiated from human induced pluripotent stem cells by Ng, Elizabeth S, Sarila, Gulcan, Li, Jacky Y, Edirisinghe, Hasindu S, Saxena, Ritika, Sun, Shicheng, Bruveris, Freya F, Labonne, Tanya, Sleebs, Nerida, Maytum, Alexander, Yow, Raymond Y, Inguanti, Chantelle, Motazedian, Ali, Calvanese, Vincenzo, Capellera-Garcia, Sandra, Ma, Feiyang, Nim, Hieu T, Ramialison, Mirana, Bonifer, Constanze, Mikkola, Hanna K A, Stanley, Edouard G, Elefanty, Andrew G

“…Hematopoietic stem cells (HSCs) derived from human induced pluripotent stem cells (iPS cells) have important biomedical applications. We identified…”
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Intellectual Property in Vaccine Innovation: Impact of Recent Patent Developments by Ng, Elizabeth Siew-Kuan

“…This chapter examines the issues on patentability of microorganisms and human genes under the US laws and analyzes their influence on vaccine innovation. The…”
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Secondary structures, dynamics, and DNA binding of the homeodomain of human SIX1 by Li, Yan, Ng, Elizabeth YiHui, Loh, Ying Ru, Gea, Chong Yu, Huang, Qiwei, Li, Qingxin, Kang, CongBao

“…Human sine oculis homeobox homolog (SIX) 1 contains a homeodomain (HD), which is important for binding to DNA. In this study, we carried out structural studies…”
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