Search Results - "Ng, Boon Tat"
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Immunophenotyping schizophrenia subtypes stratified by antipsychotic response
Published in Brain, behavior, and immunity (01-01-2025)“…•Schizophrenia patients and healthy controls have immunophenotypic differences.•Differences trend across varying degrees of antipsychotic resistance.•Findings…”
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Association between sleep quality and domains of quality of life amongst patients with first episode psychosis
Published in Health and quality of life outcomes (29-04-2020)“…There is a lack of studies exploring associations between sleep and quality of life (QOL) among patients with schizophrenia who have limited exposure to…”
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Once-daily versus divided dosing regimens of clozapine: A cross-sectional study in Singapore
Published in Schizophrenia research (01-06-2024)“…Clozapine is recognized as the gold standard medication for treatment-resistant schizophrenia. Despite the general recommendation of administering in a divided…”
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The Impact of Clozapine Delay on Clinical Outcomes in Schizophrenia
Published in The journal of clinical psychiatry (01-09-2023)“…Background: Clozapine is the drug of choice indicated for treatment-resistant schizophrenia (TRS), but delays in initiation and underutilization might have…”
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Global emotion dysregulation and maladaptive cognitive emotion regulation strategies mediate the effects of severe trauma on depressive and positive symptoms in early non-affective psychosis
Published in Schizophrenia research (01-08-2020)“…Previous research has shown that childhood trauma contributes to the onset and maintenance of psychosis. However, few studies have accounted for the effects of…”
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Association between treatment resistance and cognitive function in schizophrenia
Published in Singapore medical journal (01-10-2024)“…Treatment-resistant schizophrenia (TRS) affects around 30% of individuals with schizophrenia. About half of the patients with TRS who are treated with…”
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M215. FACTORS ASSOCIATED WITH CLOZAPINE RESPONSE AND RESISTANCE IN SCHIZOPHRENIA
Published in Schizophrenia bulletin (18-05-2020)“…Abstract Background Clozapine remains the only antipsychotic with unique efficacy in treatment resistant schizophrenia (TRS). Considerable ongoing research and…”
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Clozapine Use in First-Episode Psychosis: The Singapore Early Psychosis Intervention Programme (EPIP) Perspective
Published in The journal of clinical psychiatry (01-11-2016)“…Early symptomatic response is pertinent in improving outcomes in first-episode psychosis. One of the ways in which this may be achieved is by reducing…”
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Metabolic syndrome and cardiovascular risk between clozapine and non-clozapine antipsychotic users with schizophrenia
Published in Asian journal of psychiatry (01-08-2022)“…INTRODUCTIONClozapine use is associated with higher risks of metabolic side effects and cardiovascular diseases (CVD). Thus, this study aims to establish and…”
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Deconstructing the genetic architecture of treatment-resistant schizophrenia in East Asian ancestry
Published in Asian journal of psychiatry (01-12-2023)“…BACKGROUNDTreatment-resistant schizophrenia (TRS) affects a substantial proportion of patients who do not respond adequately to antipsychotic medications, yet…”
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F224. UTILITY OF SALIVA FOR MONITORING OF CLOZAPINE LEVELS
Published in Schizophrenia bulletin (01-04-2018)“…Abstract Background Clozapine has specific indication for use in Treatment Resistant Schizophrenia (TRS) with guidelines for therapeutic drug monitoring…”
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Prevalence, correlates and outcomes of insomnia in patients with first episode psychosis from a tertiary psychiatric institution in Singapore
Published in General hospital psychiatry (01-03-2018)“…The study aimed to evaluate the prevalence of insomnia in patients with first episode psychosis (FEP) and to explore the relationship between insomnia and…”
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Poster #S250 PRESCRIPTION PATTERNS PRIOR TO CLOZAPINE INITIATION IN FIRST-EPISODE PSYCHOSIS
Published in Schizophrenia research (01-04-2014)Get full text
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