Search Results - "Newton, Lucas M"
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Osteosarcoma cells depend on MCL-1 for survival, and osteosarcoma metastases respond to MCL-1 antagonism plus regorafenib in vivo
Published in BMC cancer (04-11-2024)“…Abstract Osteosarcoma is the most common form of primary bone cancer, which primarily afflicts children and adolescents. Chemotherapy, consisting of…”
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Erythroblast enucleation at a glance
Published in Journal of cell science (01-10-2024)“…Erythroid enucleation, the penultimate step in mammalian erythroid terminal differentiation, is a unique cellular process by which red blood cells…”
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E-cadherin in developing murine T cells controls spindle alignment and progression through β-selection
Published in Science advances (18-01-2023)“…A critical stage of T cell development is β-selection; at this stage, the T cell receptor β (TCRβ) chain is generated, and the developing T cell starts to…”
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Stepwise progression of β-selection during T cell development involves histone deacetylation
Published in Life science alliance (01-01-2023)“…During T cell development, the first step in creating a unique T cell receptor (TCR) is genetic recombination of the TCRβ chain. The quality of the new TCRβ is…”
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The Birth of the Red Blood Cell: Dynamics of Erythroid Enucleation in the Bone Marrow Niche
Published in Blood (15-11-2022)Get full text
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