Search Results - "Newsome, T."

Orbitofrontal Cortex Value Signals Depend on Fixation Location during Free Viewing by McGinty, Vincent B., Rangel, Antonio, Newsome, William T.

“…In the natural world, monkeys and humans judge the economic value of numerous competing stimuli by moving their gaze from one object to another, in a rapid…”
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Effects of Cortical Microstimulation on Confidence in a Perceptual Decision by Fetsch, Christopher R., Kiani, Roozbeh, Newsome, William T., Shadlen, Michael N.

“…Decisions are often associated with a degree of certainty, or confidence—an estimate of the probability that the chosen option will be correct. Recent…”
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Effective Parameters for Ultrasound-Induced In Vivo Neurostimulation by King, Randy L, Brown, Julian R, Newsome, William T, Pauly, Kim Butts

“…Abstract Ultrasound-induced neurostimulation has recently gained increasing attention, but little is known about the mechanisms by which it affects neural…”
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Laminar differences in decision-related neural activity in dorsal premotor cortex by Chandrasekaran, Chandramouli, Peixoto, Diogo, Newsome, William T., Shenoy, Krishna V.

“…Dorsal premotor cortex is implicated in somatomotor decisions. However, we do not understand the temporal patterns and laminar organization of decision-related…”
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Local Field Potential in Cortical Area MT: Stimulus Tuning and Behavioral Correlations by Liu, Jing, Newsome, William T

“…Low-frequency electrical signals like those that compose the local field potential (LFP) can be detected at substantial distances from their point of origin…”
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Natural Grouping of Neural Responses Reveals Spatially Segregated Clusters in Prearcuate Cortex by Kiani, Roozbeh, Cueva, Christopher J., Reppas, John B., Peixoto, Diogo, Ryu, Stephen I., Newsome, William T.

“…A fundamental challenge in studying the frontal lobe is to parcellate this cortex into “natural” functional modules despite the absence of topographic maps,…”
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Estimates of the Contribution of Single Neurons to Perception Depend on Timescale and Noise Correlation by Cohen, Marlene R, Newsome, William T

“…The sensitivity of a population of neurons, and therefore the amount of sensory information available to an animal, is limited by the sensitivity of single…”
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Opportunities and limitations of genetically modified nonhuman primate models for neuroscience research by Feng, Guoping, Jensen, Frances E, Greely, Henry T, Okano, Hideyuki, Treue, Stefan, Roberts, Angela C, Fox, James G, Caddick, Sarah, Poo, Mu-Ming, Newsome, William T, Morrison, John H

“…The recently developed new genome-editing technologies, such as the CRISPR/Cas system, have opened the door for generating genetically modified nonhuman…”
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Decoding and perturbing decision states in real time by Peixoto, Diogo, Verhein, Jessica R., Kiani, Roozbeh, Kao, Jonathan C., Nuyujukian, Paul, Chandrasekaran, Chandramouli, Brown, Julian, Fong, Sania, Ryu, Stephen I., Shenoy, Krishna V., Newsome, William T.

“…In dynamic environments, subjects often integrate multiple samples of a signal and combine them to reach a categorical judgment 1 . The process of deliberation…”
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Matching Behavior and the Representation of Value in the Parietal Cortex by Sugrue, Leo P., Corrado, Greg S., Newsome, William T.

“…Psychologists and economists have long appreciated the contribution of reward history and expectation to decision-making. Yet we know little about how specific…”
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Neural Basis of a Perceptual Decision in the Parietal Cortex (Area LIP) of the Rhesus Monkey by Shadlen, Michael N, Newsome, William T

“…  1 Howard Hughes Medical Institute, Department of Physiology and Biophysics, and Regional Primate Research Center, University of Washington, Seattle,…”
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The temporal precision of reward prediction in dopamine neurons by Fiorillo, Christopher D, Newsome, William T, Schultz, Wolfram

“…In this article, the authors report that the temporal precision of the reward prediction error signal encoded by midbrain dopamine neurons declines as the…”
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Integration of sensory and reward information during perceptual decision-making in lateral intraparietal cortex (LIP) of the macaque monkey by Rorie, Alan E, Gao, Juan, McClelland, James L, Newsome, William T

“…Single neurons in cortical area LIP are known to carry information relevant to both sensory and value-based decisions that are reported by eye movements. It is…”
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Differential encoding in prefrontal cortex projection neuron classes across cognitive tasks by Lui, Jan H., Nguyen, Nghia D., Grutzner, Sophie M., Darmanis, Spyros, Peixoto, Diogo, Wagner, Mark J., Allen, William E., Kebschull, Justus M., Richman, Ethan B., Ren, Jing, Newsome, William T., Quake, Stephen R., Luo, Liqun

“…Single-cell transcriptomics has been widely applied to classify neurons in the mammalian brain, while systems neuroscience has historically analyzed the…”
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Dynamics of Neural Population Responses in Prefrontal Cortex Indicate Changes of Mind on Single Trials by Kiani, Roozbeh, Cueva, Christopher J., Reppas, John B., Newsome, William T.

“…Decision making is a complex process in which different sources of information are combined into a decision variable (DV) that guides action [1, 2]…”
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Choosing the greater of two goods: neural currencies for valuation and decision making by Sugrue, Leo P, Newsome, William T, Corrado, Greg S

“…To make adaptive decisions, animals must evaluate the costs and benefits of available options. The nascent field of neuroeconomics has set itself the ambitious…”
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Value and choice as separable and stable representations in orbitofrontal cortex by Kimmel, Daniel L., Elsayed, Gamaleldin F., Cunningham, John P., Newsome, William T.

“…Value-based decision-making requires different variables—including offer value, choice, expected outcome, and recent history—at different times in the decision…”
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Deviation from the matching law reflects an optimal strategy involving learning over multiple timescales by Iigaya, Kiyohito, Ahmadian, Yashar, Sugrue, Leo P., Corrado, Greg S., Loewenstein, Yonatan, Newsome, William T., Fusi, Stefano

“…Behavior deviating from our normative expectations often appears irrational. For example, even though behavior following the so-called matching law can…”
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Correlated Firing in Macaque Visual Area MT: Time Scales and Relationship to Behavior by Bair, Wyeth, Zohary, Ehud, Newsome, William T

“…We studied the simultaneous activity of pairs of neurons recorded with a single electrode in visual cortical area MT while monkeys performed a direction…”
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Vertebrate scavenging in Australia is shaped by a complex interplay of bioregional, seasonal and habitat factors by Spencer, E. E., Dickman, C. R., Greenville, A., Barton, P., Ritchie, E. G., Newsome, T. M.

“…Carcass scavenging by vertebrates is a critical ecosystem service that is influenced by environmental factors such as season and habitat. However, there is…”
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