Search Results - "Newsome, Scott D"
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Unsupervised MR harmonization by learning disentangled representations using information bottleneck theory
Published in NeuroImage (Orlando, Fla.) (01-11-2021)“…•Unsupervised MR harmonization without traveling subjects.•Unified latent space for MR contrast synthesis.•A novel framework for disentangling contrast and…”
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2
Clinical biomarkers differentiate myelitis from vascular and other causes of myelopathy
Published in Neurology (02-01-2018)“…OBJECTIVETo assess the predictive value of the initial clinical and paraclinical features in the differentiation of inflammatory myelopathies from other causes…”
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Microcystic macular oedema, thickness of the inner nuclear layer of the retina, and disease characteristics in multiple sclerosis: a retrospective study
Published in Lancet neurology (01-11-2012)“…Summary Background Microcystic macular oedema (MMO) of the retinal inner nuclear layer (INL) has been identified in patients with multiple sclerosis (MS) by…”
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4
Optical coherence tomography segmentation reveals ganglion cell layer pathology after optic neuritis
Published in Brain (London, England : 1878) (01-02-2012)“…Post-mortem ganglion cell dropout has been observed in multiple sclerosis; however, longitudinal in vivo assessment of retinal neuronal layers following acute…”
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COVID-19 risk factors and outcomes in individuals with stiff person syndrome spectrum disorders before and after omicron
Published in Orphanet journal of rare diseases (27-09-2024)“…Stiff person syndrome spectrum disorders (SPSD) are rare, disabling disorders of the nervous system that are associated with risk factors for Coronavirus…”
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Differentiating neuromyelitis optica from other causes of longitudinally extensive transverse myelitis on spinal magnetic resonance imaging
Published in Multiple sclerosis (01-03-2016)“…Background: Although spinal magnetic resonance imaging (MRI) findings of neuromyelitis optica (NMO) have been described, there is limited data available that…”
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7
Primary retinal pathology in multiple sclerosis as detected by optical coherence tomography
Published in Brain (London, England : 1878) (01-02-2011)“…Optical coherence tomography studies in multiple sclerosis have primarily focused on evaluation of the retinal nerve fibre layer. The aetiology of retinal…”
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8
In vivo identification of morphologic retinal abnormalities in neuromyelitis optica
Published in Neurology (09-04-2013)“…To assess eyes with neuromyelitis optica (NMO) for morphologic retinal abnormalities utilizing high-definition optical coherence tomography (OCT) imaging. In…”
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Stiff Person Spectrum Disorders—An Update and Outlook on Clinical, Pathophysiological and Treatment Perspectives
Published in Biomedicines (01-09-2023)“…Stiff person spectrum disorders (SPSD) are paradigm autoimmune movement disorders characterized by stiffness, spasms and hyperekplexia. Though rare, SPSD…”
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10
No Evidence of Disease Activity (NEDA) as a Clinical Assessment Tool for Multiple Sclerosis: Clinician and Patient Perspectives [Narrative Review]
Published in Neurology and therapy (01-12-2023)“…The emergence of high-efficacy therapies for multiple sclerosis (MS), which target inflammation more effectively than traditional disease-modifying therapies,…”
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11
Revisiting brain atrophy and its relationship to disability in multiple sclerosis
Published in PloS one (15-05-2012)“…Brain atrophy is a well-accepted imaging biomarker of multiple sclerosis (MS) that partially correlates with both physical disability and cognitive impairment…”
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Prevalence of non-neurological autoantibodies and related comorbidities in stiff person spectrum disorders
Published in Frontiers in neurology (2023)“…Stiff Person Syndrome Spectrum Disorders (SPSD) are a group of rare neurological disorders that can present alongside other autoimmune conditions. However, not…”
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Therapeutic plasma exchange in the management of stiff person syndrome spectrum disorders: a case series and review of the literature
Published in Therapeutic advances in neurological disorders (01-01-2023)“…Background: Stiff person syndrome spectrum disorders (SPSD) are a rare group of disabling neuroimmunological disorders. SPSD often requires immune therapies,…”
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14
The many faces of gastrointestinal dysfunction in stiff person syndrome spectrum disorders
Published in Frontiers in neurology (06-10-2023)“…Introduction The effect of stiff person syndrome spectrum disorders (SPSD) on the gastrointestinal tract (GIT) is unknown. This case series aims to…”
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Insights for Healthcare Providers on Shared Decision-Making in Multiple Sclerosis: A Narrative Review
Published in Neurology and therapy (01-02-2024)“…Shared decision-making (SDM) between the patient and their healthcare provider (HCP) in developing treatment plans is increasingly recognized as central to…”
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Brain and Muscle Metabolic Changes by FDG-PET in Stiff Person Syndrome Spectrum Disorders
Published in Frontiers in neurology (17-09-2021)“…Objective: To report clinical characteristics and fluorodeoxyglucose positron emission tomography (FDG-PET) findings in the brain and muscles of individuals…”
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Cognitive and Mood Profiles Among Patients With Stiff Person Syndrome Spectrum Disorders
Published in Frontiers in neurology (27-05-2022)“…An emerging body of evidence suggests that changes in cognitive and emotional function are common aspects of stiff person spectrum disorders (SPSD). We sought…”
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The Impact of Dynamic Balance Measures on Walking Performance in Multiple Sclerosis
Published in Neurorehabilitation and neural repair (01-01-2015)“…Background: Static posture imbalance and gait dysfunction are common in individuals with multiple sclerosis (MS). Although the impact of strength and static…”
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Stiff person syndrome spectrum disorders; more than meets the eye
Published in Journal of neuroimmunology (15-08-2022)“…Stiff person syndrome spectrum disorders (SPSD) are a group of rare neuroimmunological disorders that often include painful spasms and rigidity. However,…”
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An update on the evidence base for peginterferon β1a in the treatment of relapsing–remitting multiple sclerosis
Published in Therapeutic Advances in Neurological Disorders (01-11-2016)“…Peginterferon β1a is a modified form of interferon β1a with a polyethylene glycol (PEG) group attached to the α-amino group of the N terminus of the interferon…”
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