Search Results - "Newport, D."

Ketamine and Other NMDA Antagonists: Early Clinical Trials and Possible Mechanisms in Depression by Newport, D. Jeffrey, Carpenter, Linda L., McDonald, William M., Potash, James B., Tohen, Mauricio, Nemeroff, Charles B.

“…Objective:The authors conducted a systematic review and meta-analysis of ketamine and other N-methyl-d-aspartate (NMDA) receptor antagonists in the treatment…”
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Antiepileptic drug clearances during pregnancy and clinical implications for women with epilepsy by Voinescu, P Emanuela, Park, Suna, Chen, Li Q, Stowe, Zachary N, Newport, D Jeffrey, Ritchie, James C, Pennell, Page B

“…OBJECTIVETo characterize the magnitude and time course of pregnancy-related clearance changes for different antiepileptic drugs (AEDs)levetiracetam,…”
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Maternal depression and infant cortisol: influences of timing, comorbidity and treatment by Brennan, Patricia A., Pargas, Rebecca, Walker, Elaine F., Green, Paula, Jeffrey Newport, D., Stowe, Zachary

“…Background:  The current study examines the relationship between maternal depression and infant cortisol concentrations. The potential roles of comorbid…”
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The link between childhood trauma and depression: Insights from HPA axis studies in humans by Heim, Christine, Newport, D. Jeffrey, Mletzko, Tanja, Miller, Andrew H, Nemeroff, Charles B

“…Summary Childhood trauma is a potent risk factor for developing depression in adulthood, particularly in response to additional stress. We here summarize…”
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Medical Comorbidities in Bipolar Disorder by Sinha, Aktriti, Shariq, Anam, Said, Khaled, Sharma, Abhinav, Jeffrey Newport, D., Salloum, Ihsan M.

“…Purpose of Review Bipolar disorder (BD) medical comorbidity presents significant clinical and public health concerns with serious impact on health. The aim of…”
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Early predictive biomarkers for postpartum depression point to a role for estrogen receptor signaling by Mehta, D, Newport, D J, Frishman, G, Kraus, L, Rex-Haffner, M, Ritchie, J C, Lori, A, Knight, B T, Stagnaro, E, Ruepp, A, Stowe, Z N, Binder, E B

“…Postpartum depression (PPD) affects approximately 13% of women and has a negative impact on mother and infant, hence reliable biological tests for early…”
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Altered Pituitary-Adrenal Axis Responses to Provocative Challenge Tests in Adult Survivors of Childhood Abuse by Heim, Christine, Newport, D. Jeffrey, Bonsall, Robert, Miller, Andrew H., Nemeroff, Charles B.

“…OBJECTIVE: Early adverse life events may predispose individuals to the development of mood and anxiety disorders in adulthood, perhaps by inducing persistent…”
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Validity of depression rating scales during pregnancy and the postpartum period: Impact of trimester and parity by Ji, Shuang, Long, Qi, Jeffrey Newport, D, Na, Hyeji, Knight, Bettina, Zach, Elizabeth B, Morris, Natalie J, Kutner, Michael, Stowe, Zachary N

“…Abstract The objective of the current study was to delineate the optimal cutpoints for depression rating scales during pregnancy and the postpartum period and…”
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Experimental evaluation of a patient specific Brachio-Cephalic Arterio Venous Fistula (AVF): Velocity flow conditions under steady and pulsatile waveforms by Alam, N., Walsh, M., Newport, D.

“…•Due to the low pulsatility index, steady, phase average and average of the waveform flow structures do not vary suggesting that modelling steady flow is…”
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Pituitary-Adrenal and Autonomic Responses to Stress in Women After Sexual and Physical Abuse in Childhood by Heim, Christine, Newport, D. Jeffrey, Heit, Stacey, Graham, Yolanda P, Wilcox, Molly, Bonsall, Robert, Miller, Andrew H, Nemeroff, Charles B

“…CONTEXT Evidence suggests that early adverse experiences play a preeminent role in development of mood and anxiety disorders and that corticotropin-releasing…”
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Lower CSF oxytocin concentrations in women with a history of childhood abuse by Heim, C, Young, L J, Newport, D J, Mletzko, T, Miller, A H, Nemeroff, C B

“…Early-life disruption of the parent–child relationship, for example, in the form of abuse, neglect or loss, dramatically increases risk for psychiatric, as…”
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Maternal prenatal depression and epigenetic age deceleration: testing potentially confounding effects of prenatal stress and SSRI use by McKenna, Brooke G., Hendrix, Cassandra L., Brennan, Patricia A., Smith, Alicia K., Stowe, Zachary N., Newport, D. Jeffrey, Knight, Anna K.

“…Previous studies suggest epigenetic alterations may contribute to the association between maternal prenatal depression and adverse offspring outcomes…”
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The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K by Bushell, Simon R., Pike, Ashley C. W., Falzone, Maria E., Rorsman, Nils J. G., Ta, Chau M., Corey, Robin A., Newport, Thomas D., Christianson, John C., Scofano, Lara F., Shintre, Chitra A., Tessitore, Annamaria, Chu, Amy, Wang, Qinrui, Shrestha, Leela, Mukhopadhyay, Shubhashish M. M., Love, James D., Burgess-Brown, Nicola A., Sitsapesan, Rebecca, Stansfeld, Phillip J., Huiskonen, Juha T., Tammaro, Paolo, Accardi, Alessio, Carpenter, Elisabeth P.

“…Membranes in cells have defined distributions of lipids in each leaflet, controlled by lipid scramblases and flip/floppases. However, for some intracellular…”
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Lamotrigine in pregnancy : Clearance, therapeutic drug monitoring, and seizure frequency by PENNELL, P. B, PENG, L, NEWPORT, D. J, RITCHIE, J. C, KOGANTI, A, HOLLEY, D. K, NEWMAN, M, STOWE, Z. N

“…To characterize the magnitude and course of alterations in total and free lamotrigine (LTG) clearance (Cl) during pregnancy and the postpartum period, to…”
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Risk of Recurrence in Women With Bipolar Disorder During Pregnancy: Prospective Study of Mood Stabilizer Discontinuation by Viguera, Adele C., Whitfield, Theodore, Baldessarini, Ross J., Newport, D. Jeffrey, Stowe, Zachary, Reminick, Alison, Zurick, Amanda, Cohen, Lee S.

“…Objective: This study estimated the risk of recurrence of mood episodes among women with a history of bipolar disorder who continued or discontinued treatment…”
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Positive affect improves a transdiagnostic model of perinatal depression symptoms by Pingeton, Blaire C., Cochran, Amy, Goodman, Sherryl H., Laurent, Heidemarie, Sbrilli, Marissa D., Knight, Bettina, Newport, D. Jeffrey, Stowe, Zachary N.

“…Accurate measurement of perinatal depression is vital. We aimed to 1) test whether a factor that measured positive affect (PA) bettered a transdiagnostic model…”
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Relapse of Major Depression During Pregnancy in Women Who Maintain or Discontinue Antidepressant Treatment by Cohen, Lee S, Altshuler, Lori L, Harlow, Bernard L, Nonacs, Ruta, Newport, D. Jeffrey, Viguera, Adele C, Suri, Rita, Burt, Vivien K, Hendrick, Victoria, Reminick, Alison M, Loughead, Ada, Vitonis, Allison F, Stowe, Zachary N

“…CONTEXT Pregnancy has historically been described as a time of emotional well-being, providing “protection” against psychiatric disorder. However, systematic…”
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Silver Nanoparticle Induced Blood-Brain Barrier Inflammation and Increased Permeability in Primary Rat Brain Microvessel Endothelial Cells by Trickler, William J., Lantz, Susan M., Murdock, Richard C., Schrand, Amanda M., Robinson, Bonnie L., Newport, Glenn D., Schlager, John J., Oldenburg, Steven J., Paule, Merle G., Slikker, William, Hussain, Saber M., Ali, Syed F.

“…The current report examines the interactions of silver nanoparticles (Ag-NPs) with the cerebral microvasculature to identify the involvement of proinflammatory…”
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The severity and role of somatic depressive symptoms in psychological networks in a longitudinal sample of peripartum women by Baez, Lara Michelle, Newport, D. Jeffrey, Stowe, Zachary N., Knight, Bettina T., Heller, Aaron Shain

“…The inclusion of somatic symptoms in assessing peripartum depression (PPD), which encompasses depression during pregnancy and the postpartum period, has…”
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Implementation of Advanced Methods for Reproductive Pharmacovigilance in Autism: A Meta-Analysis of the Effects of Prenatal Antidepressant Exposure by Vega, Monica L, Newport, Graham C, Bozhdaraj, Durim, Saltz, Samantha B, Nemeroff, Charles B, Newport, D. Jeffrey

“…Objective:Observational studies of prenatal antidepressant safety are hindered by methodological concerns, including susceptibility to surveillance bias. Some…”
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