Search Results - "Newman, Eric"

Glial cell regulation of neuronal activity and blood flow in the retina by release of gliotransmitters by Newman, Eric A.

“…Astrocytes in the brain release transmitters that actively modulate neuronal excitability and synaptic efficacy. Astrocytes also release vasoactive agents that…”
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Functional Hyperemia and Mechanisms of Neurovascular Coupling in the Retinal Vasculature by Newman, Eric A

“…The retinal vasculature supplies cells of the inner and middle layers of the retina with oxygen and nutrients. Photic stimulation dilates retinal arterioles…”
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Astrocyte regulation of blood flow in the brain by MacVicar, Brian A, Newman, Eric A

“…Neuronal activity results in increased blood flow in the brain, a response named functional hyperemia. Astrocytes play an important role in mediating this…”
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Cellular and physiological mechanisms underlying blood flow regulation in the retina and choroid in health and disease by Kur, Joanna, Newman, Eric A., Chan-Ling, Tailoi

“…We review the cellular and physiological mechanisms responsible for the regulation of blood flow in the retina and choroid in health and disease. Due to the…”
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Regulation of blood flow in the retinal trilaminar vascular network by Kornfield, Tess E, Newman, Eric A

“…Light stimulation evokes neuronal activity in the retina, resulting in the dilation of retinal blood vessels and increased blood flow. This response, named…”
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Glial and neuronal control of brain blood flow by Attwell, David, Buchan, Alastair M, Charpak, Serge, Lauritzen, Martin, MacVicar, Brian A, Newman, Eric A

“…Blood flow in the brain is regulated by neurons and astrocytes. Knowledge of how these cells control blood flow is crucial for understanding how neural…”
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Mechanisms Mediating Functional Hyperemia in the Brain by Nippert, Amy R., Biesecker, Kyle R., Newman, Eric A.

“…Neuronal activity within the brain evokes local increases in blood flow, a response termed functional hyperemia. This response ensures that active neurons…”
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Astrocyte β-Adrenergic Receptor Activity Regulates NMDA Receptor Signaling of Medial Prefrontal Cortex Pyramidal Neurons by Del Franco, Armani P, Newman, Eric A

“…Glutamate spillover from the synapse is tightly regulated by astrocytes, limiting the activation of extrasynaptically located NMDA receptors (NMDAR). The…”
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Purinergic control of vascular tone in the retina by Kur, Joanna, Newman, Eric A.

“…Key points The blood supply to the CNS is controlled by the tone of arteries and arterioles. However, little is known about purinergic regulation of vascular…”
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New roles for astrocytes: Regulation of synaptic transmission by Newman, Eric A

“…Although glia often envelop synapses, they have traditionally been viewed as passive participants in synaptic function. Recent evidence has demonstrated,…”
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Glial Cell Calcium Signaling Mediates Capillary Regulation of Blood Flow in the Retina by Biesecker, Kyle R, Srienc, Anja I, Shimoda, Angela M, Agarwal, Amit, Bergles, Dwight E, Kofuji, Paulo, Newman, Eric A

“…The brain is critically dependent on the regulation of blood flow to nourish active neurons. One widely held hypothesis of blood flow regulation holds that…”
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Whisker-evoked neurovascular coupling is preserved during hypoglycemia in mouse cortical arterioles and capillaries by Nippert, Amy R, Chiang, Pei-Pei, Newman, Eric A

“…Hypoglycemia is a serious complication of insulin treatment of diabetes that can lead to coma and death. Neurovascular coupling, which mediates increased local…”
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Glial Cells Dilate and Constrict Blood Vessels: A Mechanism of Neurovascular Coupling by Metea, Monica R, Newman, Eric A

“…Neuronal activity evokes localized changes in blood flow. Although this response, termed neurovascular coupling, is widely used to monitor human brain function…”
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Inhibition of inducible nitric oxide synthase reverses the loss of functional hyperemia in diabetic retinopathy by Mishra, Anusha, Newman, Eric A.

“…Neuronal activity leads to arteriole dilation and increased blood flow in retinal vessels. This response, termed functional hyperemia, is diminished in the…”
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Astrocyte regulation of cerebral blood flow during hypoglycemia by Nippert, Amy R, Chiang, Pei-Pei, Del Franco, Armani P, Newman, Eric A

“…Hypoglycemia triggers increases in cerebral blood flow (CBF), augmenting glucose supply to the brain. We have tested whether astrocytes, which can regulate…”
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Glial Cell Inhibition of Neurons by Release of ATP by Newman, Eric A

“…ATP is released by neurons and functions as a neurotransmitter and modulator in the CNS. Here I show that ATP released from glial cells can also serve as a…”
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Dilation of cortical capillaries is not related to astrocyte calcium signaling by Del Franco, Armani P., Chiang, Pei‐Pei, Newman, Eric A.

“…The brain requires an adequate supply of oxygen and nutrients to maintain proper function as neuronal activity varies. This is achieved, in part, through…”
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Oxygen modulation of neurovascular coupling in the retina by Mishra, Anusha, Hamid, Arif, Newman, Eric A

“…Neurovascular coupling is a process through which neuronal activity leads to local increases in blood flow in the central nervous system. In brain slices, 100%…”
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Regulation of blood flow in diabetic retinopathy by Nippert, Amy R, Newman, Eric A

“…Blood flow in the retina increases in response to light-evoked neuronal activity, ensuring that retinal neurons receive an adequate supply of oxygen and…”
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Cellular mechanisms mediating activity‐dependent extracellular space shrinkage in the retina by Chiang, Pei‐Pei, Kuo, Sidney P., Newman, Eric A.

“…Volume transmission plays an essential role in CNS function, with neurotransmitters released from synapses diffusing through the extracellular space (ECS) to…”
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