Search Results - "Newman, Ann"

Interrelationships Between Structure and the Properties of Amorphous Solids of Pharmaceutical Interest by Zografi, George, Newman, Ann

“…This commentary explores fundamental issues associated with the structure of amorphous solids of pharmaceutical interest in terms of the effects of such…”
Get more information

What We Need to Know about Solid-State Isothermal Crystallization of Organic Molecules from the Amorphous State below the Glass Transition Temperature by Newman, Ann, Zografi, George

“…In this Perspective, the authors have examined various principles associated with the isothermal crystallization of organic molecules from the amorphous state…”
Get full text

Assessing the performance of amorphous solid dispersions by Newman, Ann, Knipp, Gregory, Zografi, George

“…The characterization and performance of stable amorphous solid dispersion systems were evaluated in 40 research papers reporting active pharmaceutical…”
Get more information

Dietary protein intake is not associated with 5-y change in mid-thigh muscle cross-sectional area by computed tomography in older adults: the Health, Aging, and Body Composition (Health ABC) Study by Verreijen, Amely M, Engberink, Mariëlle F, Houston, Denise K, Brouwer, Ingeborg A, Cawthon, Peggy M, Newman, Ann B, Tylavsky, Frances A, Harris, Tamara B, Weijs, Peter J M, Visser, Marjolein

“…A higher protein intake is suggested to preserve muscle mass during aging and may therefore reduce the risk of sarcopenia. We explored whether the amount and…”
Get full text

Characterization of the "hygroscopic" properties of active pharmaceutical ingredients by Newman, Ann W, Reutzel-Edens, Susan M, Zografi, George

“…The amount of water vapor taken up by an active pharmaceutical ingredient (API) as a function of relative humidity is routinely evaluated to characterize and…”
Get more information

Perceived quality of maternal care in childhood and structure and function of mothers' brain by Kim, Pilyoung, Leckman, James F., Mayes, Linda C., Newman, Michal-Ann, Feldman, Ruth, Swain, James E.

“…Animal studies indicate that early maternal care has long‐term effects on brain areas related to social attachment and parenting, whereas neglectful mothering…”
Get full text

Characterization of amorphous API:Polymer mixtures using X-ray powder diffraction by Newman, Ann, Engers, David, Bates, Simon, Ivanisevic, Igor, Kelly, Ron C, Zografi, George

“…Recognizing limitations with the standard method of determining whether an amorphous API-polymer mixture is miscible based on the number of glass transition…”
Get more information

Chemical reactivity in solid-state pharmaceuticals: formulation implications by Byrn, Stephen R, Xu, Wei, Newman, Ann W

“…Solid-state reactions that occur in drug substances and formulations include solid-state phase transformations, dehydration/desolvation, and chemical…”
Get full text

Solid-state analysis of the active pharmaceutical ingredient in drug products by Newman, Ann W., Byrn, Stephen R.

“…The solid form of a drug substance is important when developing a new chemical entity. The crystalline form used in development is significant based on…”
Get full text

Social Support and Successful Aging in Assisted Living Residents by Howie, Laura Odell, Troutman-Jordan, Meredith, Newman, Ann M.

“…Successful aging has been associated with adequate social support. However, impaired functionality, increased dependence, multiple comorbidities, and reduced…”
Get full text

Obesity in Older Adults by Newman, Ann

“…The prevalence of obesity in the United States is increasing in all age groups. During the past 30 years, the proportion of older adults who are obese has…”
Get full text

Assessment of defects and amorphous structure produced in raffinose pentahydrate upon dehydration by Bates, Simon, Kelly, Ron C, Ivanisevic, Igor, Schields, Paul, Zografi, George, Newman, Ann W

“…The progressive conversion of crystalline raffinose pentahydrate to its amorphous form by dehydration at 60 degrees C, well below its melting temperature, was…”
Get more information

Pharmaceutical Cocrystals and Their Physicochemical Properties by Schultheiss, Nate, Newman, Ann

“…Over the last 20 years, the number of publications outlining the advances in design strategies, growing techniques, and characterization of cocrystals has…”
Get full text

Specialized Solid Form Screening Techniques by Newman, Ann

“…Solid form screening is an integral part of many development plans at various companies and includes polymorph, salt, cocrystal, amorphous, and amorphous…”
Get full text

Solid form changes during drug development: good, bad, and ugly case studies by Newman, Ann, Wenslow, Robert

“…The relevance of solid form in drug development has been well established over time. In order to fully understand drug properties, attention has been paid to…”
Get full text

New directions in pharmaceutical amorphous materials and amorphous solid dispersions, a tribute to Professor George Zografi – Proceedings of the June 2016 Land O’Lakes Conference by Newman, Ann, Hastedt, Jayne E., Yazdanian, Mehran

“…The University of Wisconsin-Madison June Land O’Lakes Conference on Research and Development is held every year and is recognized worldwide as a premier…”
Get full text

What Are the Important Factors That Influence API Crystallization in Miscible Amorphous API–Excipient Mixtures during Long-Term Storage in the Glassy State? by Newman, Ann, Zografi, George

“…In this Perspective, the authors examine the various factors that should be considered when attempting to use miscible amorphous API–excipient mixtures…”
Get full text

Perspectives on the Wetting of Solids in Pharmaceutical Systems by Newman, Ann, Zografi, George

“…Purpose The ability of water and aqueous solutions to wet relatively nonpolar pharmaceutical solids during the processing and administration of solid dosage…”
Get full text

Considerations in the Development of Physically Stable High Drug Load API- Polymer Amorphous Solid Dispersions in the Glassy State by Newman, Ann, Zografi, George

“…In this Commentary, the authors expand on their earlier studies of the solid-state long-term isothermal crystallization of amorphous API from the glassy state…”
Get more information

An Examination of Water Vapor Sorption by Multicomponent Crystalline and Amorphous Solids and Its Effects on Their Solid-State Properties by Newman, Ann, Zografi, George

“…This commentary critically evaluated the unique effects of water vapor sorption by multicomponent solid forms of active pharmaceutical ingredients (APIs), and…”
Get more information