Search Results - "Newlands, G"

Trials with the Haemonchus vaccine, Barbervax®, in ewes and lambs in a tropical environment: Nutrient supplementation improves protection in periparturient ewes by Bassetto, C.C., Almeida, F.A., Newlands, G.F.J., Smith, W.D., Castilhos, A.M., Fernandes, S., Siqueira, E.R., Amarante, A.F.T.

“…•Vaccination of grazing ewes and lambs against Haemonchus contortus.•The nutritional status affects the outcome of the vaccine against haemonchosis.•Vaccinated…”
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Attempts to vaccinate ewes and their lambs against natural infection with Haemonchus contortus in a tropical environment by Bassetto, C.C., Picharillo, M.É., Newlands, G.F.J., Smith, W.D., Fernandes, S., Siqueira, E.R., Amarante, A.F.T.

“…•A vaccine made from Haemonchus contortus was trialled in grazing sheep in Brazil.•Vaccination reduced worm burden and egg counts of H. contortus in lambs.•A…”
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Vaccination of grazing calves with antigens from the intestinal membranes of Haemonchus contortus: effects against natural challenge with Haemonchus placei and Haemonchus similis by Bassetto, C.C., Silva, M.R.L., Newlands, G.F.J., Smith, W.D., Ratti Júnior, J., Martins, C.L., Amarante, A.F.T.

“…[Display omitted] •A vaccine made from Haemonchus contortus was trialled in grazing calves in Brazil.•Repeated vaccination substantially reduced Haemonchus…”
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Phage-display library biopanning as a novel approach to identifying nematode vaccine antigens by ELLIS, S. E., NEWLANDS, G. F. J., NISBET, A. J., MATTHEWS, J. B.

“…Summary Infections with parasitic nematodes are of significant welfare and economic importance worldwide, and because of the emergence of anthelmintic…”
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Protection of calves against Haemonchus placei and Haemonchus contortus after immunization with gut membrane proteins from H. contortus by BASSETTO, C. C., SILVA, B. F., NEWLANDS, G. F. J., SMITH, W. D., AMARANTE, A. F. T.

“…Summary A vaccine containing integral membrane glycoproteins from the intestine of Haemonchus contortus was evaluated in four groups of nine worm‐free calves…”
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Attempts to immunize sheep against Haemonchus contortus using a cocktail of recombinant proteases derived from the protective antigen, H-gal-GP by CACHAT, E, NEWLANDS, G.F.J, EKOJA, S.E, MCALLISTER, H, SMITH, W.D

“…The objective of this study was to determine whether an antigen cocktail containing recombinantly expressed versions of most of the protective proteases of…”
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Metalloendopeptidases from the intestinal brush border of Haemonchus contortus as protective antigens for sheep by Smith, W. D., Newlands, G. F. J., Smith, S. K., Pettit, D., Skuce, P. J.

“…SUMMARY Substantial protection against the economically important nematode Haemonchus contortus has been achieved by immunizing sheep with a glycoprotein…”
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Molecular characterization of a family of metalloendopeptidases from the intestinal brush border of Haemonchus contortus by Newlands, G F J, Skuce, P J, Nisbet, A J, Redmond, D L, Smith, S K, Pettit, D, Smith, W D

“…Substantial protection against the economically important parasitic nematode Haemonchus contortus has been achieved by immunizing sheep with a glycoprotein…”
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Aspartyl proteases from the intestinal brush border of Haemonchus contortus as protective antigens for sheep by Smith, W. D., Skuce, P. J., Newlands, G. F. J., Smith, S. K., Pettit, D.

“…SUMMARY A novel pepsin‐like aspartyl protease was identified as a component of Haemonchus galactose‐containing glycoprotein (H‐gal‐GP), which is an integral…”
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Molecular cloning and characterization of gut-derived cysteine proteinases associated with a host protective extract from Haemonchus contortus by Skuce, P J, Redmond, D L, Liddell, S, Stewart, E M, Newlands, G F, Smith, W D, Knox, D P

“…Cysteine proteinases have been implicated in the protection conferred by vaccination with detergent-soluble extracts of Haemonchus contortus. In the present…”
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A comparison of traditional road safety assessment methods and the newly developed ‘road safety deserts’ approach by Vanderschuren, M J W A, Newlands, A G

“…Road fatalities were labelled a pandemic as early as 1973 (BMJ 1973). The number of road fatalities reached 1.35 million in 2016. Currently over 3 500 people…”
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Cloning and expression of cystatin, a potent cysteine protease inhibitor from the gut of Haemonchus contortus by Newlands, G F, Skuce, P J, Knox, D P, Smith, W D

“…A cDNA encoding a cysteine protease inhibitor (cystatin) was identified by immunoscreening a Haemonchus contortus cDNA library with antisera from lambs…”
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Functional relationships between sensory nerve fibers and mast cells of dura mater in normal and inflammatory conditions by Dimitriadou, V, Rouleau, A, Trung Tuong, M.D, Newlands, G.J.F, Miller, H.R.P, Luffau, G, Schwartz, J.-C, Garbarg, M

“…In this study, we have characterized the phenotype of mast cells in rat dura mater and their topological and functional relationships with C-fibers in normal…”
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Presence of the LDNF glycan on the host‐protective H‐gal‐GP fraction from Haemonchus contortus by Geldhof, P., Newlands, G. F. J., Nyame, K., Cummings, R., Smith, W. D., Knox, D. P.

“…SUMMARY Immunization of sheep with the gut membrane‐associated protein complex H‐gal‐GP of adult Haemonchus contortus induces high levels of protection against…”
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Release of the mucosal mast cell granule chymase, rat mast cell protease-II, during anaphylaxis is associated with the rapid development of paracellular permeability to macromolecules in rat jejunum by Scudamore, C L, Thornton, E M, McMillan, L, Newlands, G F, Miller, H R

“…The soluble granule chymase, rat mast cell protease-II (RMCP-II), is abundantly expressed in intestinal mucosal mast cells (MMC) but its function is not known…”
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Activation of precursors for matrix metalloproteinases 1 (interstitial collagenase) and 3 (stromelysin) by rat mast-cell proteinases I and II by Suzuki, K, Lees, M, Newlands, G F, Nagase, H, Woolley, D E

“…Histological studies have previously demonstrated an association between mast-cell activation/degranulation and areas of connective-tissue lysis in vivo; in…”
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Theology in the Public Square: Church, Academy and Nation. By Gavin D'Costa. Pp. xiv + 247. (Challenges in Contemporary Theology.) Malden, MA/Oxford, UK/Carlton, Australia: Blackwell Publishing, 2005. isbn 1 4051 3509 2 and 3510 8. Hardback £50; paper £19.99 by Newlands, G. M.

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Mast cell heterogeneity in the gastrointestinal tract: variable expression of mouse mast cell protease-1 (mMCP-1) in intraepithelial mucosal mast cells in nematode-infected and normal BALB/c mice by Scudamore, CL, McMillan, L, Thornton, EM, Wright, SH, Newlands, GF, Miller, HR

“…Soluble granule chymases in rodent intestinal mucosal mast cells (IMMCs) may play an important role in altering epithelial permeability during immediate…”
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The nature and prospects for gut membrane proteins as vaccine candidates for Haemonchus contortus and other ruminant trichostrongyloids by Knox, David P., Redmond, Diane L., Newlands, George F., Skuce, Philip J., Pettit, Dan, Smith, W.David

“…Substantial progress has been made in the last decade in identifying several antigens from Haemonchus contortus which, in their native form, stimulate useful…”
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Cloning and characterization of a beta-galactoside-binding protein (galectin) from the gut of the gastrointestinal nematode parasite Haemonchus contortus by Newlands, G F, Skuce, P J, Knox, D P, Smith, S K, Smith, W D

“…A cDNA encoding a beta-galactoside-binding lectin (galectin) was identified by immunoscreening a Haemonchus contortus cDNA library with antisera from lambs…”
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