Search Results - "Newhart, Alyshia"
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Sp100A promotes chromatin decondensation at a cytomegalovirus-promoter-regulated transcription site
Published in Molecular biology of the cell (01-05-2013)“…Promyelocytic leukemia nuclear bodies (PML-NBs)/nuclear domain 10s (ND10s) are nuclear structures that contain many transcriptional and chromatin regulatory…”
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HSV-1 Remodels Host Telomeres to Facilitate Viral Replication
Published in Cell reports (Cambridge) (24-12-2014)“…Telomeres protect the ends of cellular chromosomes. We show here that infection with herpes simplex virus 1 (HSV-1) results in chromosomal structural…”
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Single Cell Analysis of RNA-mediated Histone H3.3 Recruitment to a Cytomegalovirus Promoter-regulated Transcription Site
Published in The Journal of biological chemistry (05-07-2013)“…Unlike the core histones, which are incorporated into nucleosomes concomitant with DNA replication, histone H3.3 is synthesized throughout the cell cycle and…”
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Seeing Is Believing: Visualizing Transcriptional Dynamics in Single Cells
Published in Journal of cellular physiology (01-03-2014)“…For a gene to be expressed, the functions of multiple molecular machines must be coordinated at the site of transcription. To understand the role of nuclear…”
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Single-cell analysis of Daxx and ATRX-dependent transcriptional repression
Published in Journal of cell science (15-11-2012)“…Histone H3.3 is a constitutively expressed H3 variant implicated in the epigenetic inheritance of chromatin structures. Recently, the PML-nuclear body…”
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6
RNase P protein subunit Rpp29 represses histone H3.3 nucleosome deposition
Published in Molecular biology of the cell (01-04-2016)“…In mammals, histone H3.3 is a critical regulator of transcription state change and heritability at both euchromatin and heterochromatin. The H3.3-specific…”
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Initial characterization of histone H3 serine 10 O-acetylation
Published in Epigenetics (01-10-2013)“…In eukaryotic organisms, histone posttranslational modifications (PTMs) are indispensable for their role in maintaining cellular physiology, often through…”
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