Search Results - "Newbold, Retha"

Developmental exposure to endocrine-disrupting chemicals programs for reproductive tract alterations and obesity later in life by NEWBOLD, Retha R

“…Many chemicals in the environment, especially those with estrogenic activity, are able to disrupt the programming of endocrine signaling pathways established…”
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Impact of environmental endocrine disrupting chemicals on the development of obesity by Newbold, Retha R.

“…Environmental chemicals with hormone-like activity can disrupt programming of endocrine signaling pathways during development and result in adverse effects,…”
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Environmental estrogens and obesity by Newbold, Retha R., Padilla-Banks, Elizabeth, Jefferson, Wendy N.

“…Many chemicals in the environment, in particular those with estrogenic activity, can disrupt the programming of endocrine signaling pathways that are…”
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Prenatal exposure to diethylstilbestrol (DES) by Newbold, Retha R., M.S

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Prenatal Exposure to Bisphenol A at Environmentally Relevant Doses Adversely Affects the Murine Female Reproductive Tract Later in Life by Newbold, Retha R., Jefferson, Wendy N., Padilla-Banks, Elizabeth

“…Background: Exposure to endocrine-disrupting chemicals during critical developmental periods causes adverse consequences later in life; an example is prenatal…”
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Adverse Effects of the Model Environmental Estrogen Diethylstilbestrol Are Transmitted to Subsequent Generations by Newbold, Retha R, Padilla-Banks, Elizabeth, Jefferson, Wendy N

“…The synthetic estrogen diethylstilbestrol (DES) is a potent perinatal endocrine disruptor. In humans and experimental animals, exposure to DES during critical…”
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Neonatal Bisphenol-A Exposure Alters Rat Reproductive Development and Ovarian Morphology Without Impairing Activation of Gonadotropin-Releasing Hormone Neurons by Adewale, Heather B, Jefferson, Wendy N, Newbold, Retha R, Patisaul, Heather B

“…Developmental exposure to endocrine-disrupting compounds is hypothesized to adversely affect female reproductive physiology by interfering with the…”
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Estradiol, Progesterone, and Genistein Inhibit Oocyte Nest Breakdown and Primordial Follicle Assembly in the Neonatal Mouse Ovary in Vitro and in Vivo by Chen, Ying, Jefferson, Wendy N, Newbold, Retha R, Padilla-Banks, Elizabeth, Pepling, Melissa E

“…In developing mouse ovaries, oocytes develop as clusters of cells called nests or germ cell cysts. Shortly after birth, oocyte nests dissociate and granulosa…”
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In vivo effects of bisphenol A in laboratory rodent studies by Richter, Catherine A., Birnbaum, Linda S., Farabollini, Francesca, Newbold, Retha R., Rubin, Beverly S., Talsness, Chris E., Vandenbergh, John G., Walser-Kuntz, Debby R., vom Saal, Frederick S.

“…Concern is mounting regarding the human health and environmental effects of bisphenol A (BPA), a high-production-volume chemical used in synthesis of plastics…”
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Long-term adverse effects of neonatal exposure to bisphenol A on the murine female reproductive tract by Newbold, Retha R., Jefferson, Wendy N., Padilla-Banks, Elizabeth

“…The developing fetus is uniquely sensitive to perturbation by chemicals with hormone-like activity. The adverse effects of prenatal diethylstilbestrol (DES)…”
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Perinatal Environmental Exposures Affect Mammary Development, Function, and Cancer Risk in Adulthood by FENTON, Suzanne E, REED, Casey, NEWBOLD, Retha R

“…Puberty is an important transition that enables reproduction of mammalian species. Precocious puberty, specifically early thelarche (the appearance of breast…”
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Persistently Altered Epigenetic Marks in the Mouse Uterus After Neonatal Estrogen Exposure by Jefferson, Wendy N, Chevalier, Dominique M, Phelps, Jazma Y, Cantor, Amy M, Padilla-Banks, Elizabeth, Newbold, Retha R, Archer, Trevor K, Kinyamu, H. Karimi, Williams, Carmen J

“…Neonatal exposure to diethylstilbestrol (DES) causes permanent alterations in female reproductive tract gene expression, infertility, and uterine cancer in…”
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NIEHS/FDA CLARITY-BPA research program update by Heindel, Jerrold J., Newbold, Retha R., Bucher, John R., Camacho, Luísa, Delclos, K. Barry, Lewis, Sherry M., Vanlandingham, Michelle, Churchwell, Mona I., Twaddle, Nathan C., McLellen, Michelle, Chidambaram, Mani, Bryant, Matthew, Woodling, Kellie, Costa, Gonçalo Gamboa da, Ferguson, Sherry A., Flaws, Jodi, Howard, Paul C., Walker, Nigel J., Zoeller, R. Thomas, Fostel, Jennifer, Favaro, Carolyn, Schug, Thaddeus T.

“…Bisphenol A (BPA) is a chemical used in the production of numerous consumer products resulting in potential daily human exposure to this chemical. The FDA…”
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A round robin approach to the analysis of bisphenol A (BPA) in human blood samples by Vandenberg, Laura N, Gerona, Roy R, Kannan, Kurunthachalam, Taylor, Julia A, van Breemen, Richard B, Dickenson, Carrie A, Liao, Chunyang, Yuan, Yang, Newbold, Retha R, Padmanabhan, Vasantha, Vom Saal, Frederick S, Woodruff, Tracey J

“…Human exposure to bisphenol A (BPA) is ubiquitous, yet there are concerns about whether BPA can be measured in human blood. This Round Robin was designed to…”
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The Conflict between Regulatory Agencies over the 20,000-Fold Lowering of the Tolerable Daily Intake (TDI) for Bisphenol A (BPA) by the European Food Safety Authority (EFSA) by Vom Saal, Frederick S, Antoniou, Michael, Belcher, Scott M, Bergman, Ake, Bhandari, Ramji K, Birnbaum, Linda S, Cohen, Aly, Collins, Terrence J, Demeneix, Barbara, Fine, Anne Marie, Flaws, Jodi A, Gayrard, Veronique, Goodson, 3rd, William H, Gore, Andrea C, Heindel, Jerrold J, Hunt, Patricia A, Iguchi, Taisen, Kassotis, Christopher D, Kortenkamp, Andreas, Mesnage, Robin, Muncke, Jane, Myers, John Peterson, Nadal, Angel, Newbold, Retha R, Padmanabhan, Vasantha, Palanza, Paola, Palma, Zandra, Parmigiani, Stefano, Patrick, Lyn, Prins, Gail S, Rosenfeld, Cheryl S, Skakkebaek, Niels E, Sonnenschein, Carlos, Soto, Ana M, Swan, Shanna H, Taylor, Julia A, Toutain, Pierre-Louis, von Hippel, Frank A, Welshons, Wade V, Zalko, Daniel, Zoeller, R Thomas

“…The European Food Safety Authority (EFSA) recommended lowering their estimated tolerable daily intake (TDI) for bisphenol A (BPA) 20,000-fold to . BPA is an…”
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Human and animal evidence of potential transgenerational inheritance of health effects: An evidence map and state-of-the-science evaluation by Walker, Vickie R., Boyles, Abee L., Pelch, Katherine E., Holmgren, Stephanie D., Shapiro, Andrew J., Blystone, Chad R., Devito, Michael J., Newbold, Retha R., Blain, Robyn, Hartman, Pamela, Thayer, Kristina A., Rooney, Andrew A.

“…An increasing number of reports suggest early life exposures result in adverse effects in offspring who were never directly exposed; this phenomenon is termed…”
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Adverse Effects on Female Development and Reproduction in CD-1 Mice Following Neonatal Exposure to the Phytoestrogen Genistein at Environmentally Relevant Doses by Jefferson, Wendy N, Padilla-Banks, Elizabeth, Newbold, Retha R

“…Outbred female CD-1 mice were treated with genistein (Gen), the primary phytoestrogen in soy, by s.c. injections on Neonatal Days 1–5 at doses of 0.5, 5, or 50…”
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Neonatal Genistein Treatment Alters Ovarian Differentiation in the Mouse: Inhibition of Oocyte Nest Breakdown and Increased Oocyte Survival by JEFFERSON, Wendy, NEWBOLD, Retha, PADILLA-BANKS, Elizabeth, PEPLING, Melissa

“…Early in ovarian differentiation, female mouse germ cells develop in clusters called oocyte nests or germline cysts. After birth, mouse germ cell nests break…”
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Disruption of the developing female reproductive system by phytoestrogens: Genistein as an example by Jefferson, Wendy N., Padilla-Banks, Elizabeth, Newbold, Retha R.

“…Studies in our laboratory have shown that exposure to genistein causes deleterious effects on the developing female reproductive system. Mice treated…”
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Perinatal exposure to environmental estrogens and the development of obesity by Newbold, Retha R., Padilla-Banks, Elizabeth, Snyder, Ryan J., Jefferson, Wendy N.

“…Dietary substances and xenobiotic compounds with hormone‐like activity can disrupt the programming of endocrine signaling pathways that are established during…”
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