Search Results - "Newberry, Kimberly"
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Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation
Published in Genome research (01-12-2009)“…The glucocorticoid steroid hormone cortisol is released by the adrenal glands in response to stress and serves as a messenger in circadian rhythms…”
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2
Occupancy maps of 208 chromatin-associated proteins in one human cell type
Published in Nature (London) (30-07-2020)“…Transcription factors are DNA-binding proteins that have key roles in gene regulation 1 , 2 . Genome-wide occupancy maps of transcriptional regulators are…”
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3
Does semantic knowledge influence event segmentation and recall of text?
Published in Memory & cognition (01-08-2019)“…Knowledge benefits episodic memory, particularly when provided before encoding (Anderson & Pichert in Journal of Verbal Learning and Verbal Behavior , 17 (1),…”
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4
Influences of domain knowledge on segmentation and memory
Published in Memory & cognition (01-05-2021)“…Much research has shown that experts possess superior memory in their domain of expertise. This memory benefit has been proposed to be the result of various…”
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5
CETCh-seq: CRISPR epitope tagging ChIP-seq of DNA-binding proteins
Published in Genome research (01-10-2015)“…Chromatin immunoprecipitation followed by next-generation DNA sequencing (ChIP-seq) is a widely used technique for identifying transcription factor (TF)…”
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6
Differential effects of knowledge and aging on the encoding and retrieval of everyday activities
Published in Cognition (01-03-2020)“…We deconstruct continuous streams of action into smaller, meaningful events. Research has shown that the ability to segment continuous activity into such…”
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7
Semantic knowledge attenuates age-related differences in event segmentation and episodic memory
Published in Memory & cognition (01-04-2022)“…While semantic and episodic memory may be distinct memory systems, their interdependence is substantial. For instance, decades of work have shown that semantic…”
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8
Role of CCCTC binding factor (CTCF) and cohesin in the generation of single-cell diversity of Protocadherin-α gene expression
Published in Proceedings of the National Academy of Sciences - PNAS (05-06-2012)“…Extraordinary single-cell diversity is generated in the vertebrate nervous system by the combinatorial expression of the clustered protocadherin genes (Pcdhα,…”
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9
The effects of domain knowledge and event structure on event processing
Published in Memory & cognition (2023)“…Research suggests that domain knowledge facilitates memory for domain-specific information through two mechanisms: differentiation, which involves the ability…”
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10
Intricate interplay between astrocytes and motor neurons in ALS
Published in Proceedings of the National Academy of Sciences - PNAS (19-02-2013)“…ALS results from the selective and progressive degeneration of motor neurons. Although the underlying disease mechanisms remain unknown, glial cells have been…”
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11
Effects of sequence variation on differential allelic transcription factor occupancy and gene expression
Published in Genome research (01-05-2012)“…A complex interplay between transcription factors (TFs) and the genome regulates transcription. However, connecting variation in genome sequence with variation…”
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12
Evidence for multiple roles for grainyheadlike 2 in the establishment and maintenance of human mucociliary airway epithelium
Published in Proceedings of the National Academy of Sciences - PNAS (04-06-2013)“…Most of the airways of the human lung are lined by an epithelium made up of ciliated and secretory luminal cells and undifferentiated basal progenitor cells…”
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13
Characterization of human transcription factor function and patterns of gene regulation in HepG2 cells
Published in Genome research (01-11-2023)“…Transcription factors (TFs) are -acting proteins that bind -regulatory elements (CREs) in DNA to control gene expression. Here, we analyzed the genomic…”
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14
Genome-wide strand asymmetry in massively parallel reporter activity favors genic strands
Published in Genome research (01-05-2021)“…Massively parallel reporter assays (MPRAs) are useful tools to characterize regulatory elements in human genomes. An aspect of MPRAs that is not typically the…”
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15
Genomic regulation of invasion by STAT3 in triple negative breast cancer
Published in Oncotarget (31-01-2017)“…Breast cancer is a heterogeneous disease comprised of four molecular subtypes defined by whether the tumor-originating cells are luminal or basal epithelial…”
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16
Epitope Tagging ChIP-Seq of DNA Binding Proteins Using CETCh-Seq
Published in Methods in molecular biology (Clifton, N.J.) (2020)“…Chromatin immunoprecipitation followed by next-generation DNA sequencing (ChIP-seq) has been used to identify transcription factor (TF) binding proteins…”
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17
Effects of BMS-902483, an α7 nicotinic acetylcholine receptor partial agonist, on cognition and sensory gating in relation to receptor occupancy in rodents
Published in European journal of pharmacology (15-07-2017)“…The α7 nicotinic acetylcholine receptor is thought to play an important role in human cognition. Here we describe the in vivo effects of BMS-902483, a…”
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18
Temporal Chunking Makes Life’s Events More Memorable
Published in Open psychology (01-01-2019)“…Declines in episodic memory accompany both healthy aging and age-related diseases, such as dementia. Given that memory complaints are common in the aging…”
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NK1 receptor antagonism lowers occupancy requirement for antidepressant-like effects of SSRIs in the Gerbil forced swim test
Published in Neuropharmacology (01-10-2013)“…The known interactions between the serotonergic and neurokinin systems suggest that serotonin reuptake inhibitor (SSRIs) efficacy may be improved by…”
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Evidence for multiple roles for grainyhead-like 2 in the establishment and maintenance of human mucociliary airway epithelium.[corrected]
Published in Proceedings of the National Academy of Sciences - PNAS (04-06-2013)“…Most of the airways of the human lung are lined by an epithelium made up of ciliated and secretory luminal cells and undifferentiated basal progenitor cells…”
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