Search Results - "Nevinsky, G"

Natural catalytic immunoglobulins hydrolyzing histones as a link between inflammation and humoral immunity in schizophrenia by Ermakov, E., Buneva, V., Nevinsky, G.

“…IntroductionSchizophrenia pathogenesis is known to be associated with chronic low-grade inflammation. Inflammation can be caused by extracellular histones that…”
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Blood-Derived RNA- and microRNA-Hydrolyzing IgG Antibodies in Schizophrenia Patients by Ermakov, E. A., Ivanova, S. A., Buneva, V. N., Nevinsky, G. A.

“…Abzymes with various catalytic activities are the earliest statistically significant markers of existing and developing autoimmune diseases (AIDs). Currently,…”
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Exceptional Diversity of Catalytic Antibodies with Varying Activity in the Blood of Autoimmune and Viral Disease Patients by Buneva, V. N., Nevinsky, G. A.

“…Antibodies (ABs) that target autoantigens were more abundant in the blood of humans and animals suffering from certain autoimmune and viral diseases than in…”
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Catalytic antibodies in healthy humans and patients with autoimmune and viral diseases by Nevinsky, G. A., Buneva, Valentina N.

“…Antibodies have been first characterized as proteins produced by the immune system solely for binding other molecules, called antigens, with the goal of…”
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DNA-hydrolyzing antibodies of patients with schizophrenia: correlation with leading symptoms of the disease by Ermakov, E, Smirnova, L, Dmitrenok, P, Semke, A, Buneva, V, Nevinsky, G, Ivanova, S

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Heavy metal ions affect the activity of DNA glycosylases of the Fpg family by Grin, I. R, Konorovsky, P. G, Nevinsky, G. A, Zharkov, D. O

“…Prokaryotic enzymes formamidopyrimidine-DNA glycosylase (Fpg) and endonuclease VIII (Nei) and their eukaryotic homologs NEIL1, NEIL2, and NEIL3 define the Fpg…”
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Structure and mechanism of action of type IA DNA topoisomerases by Bugreev, D. V, Nevinsky, G. A

“…DNA topoisomerases are enzymes responsible for regulation of genomic DNA supercoiling. They participate in essential processes of cells such as replication,…”
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Polyreactivity of natural antibodies: Exchange by HL-fragments by Sedykh, M. A., Buneva, V. N., Nevinsky, G. A.

“…The polyreactivity of binding (formation of antibody (AB) complexes not only with specific but also with foreign antigens) is a widespread phenomenon that in…”
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Anti-DNA antibodies in the blood of patients with schizophrenia possess DNA-hydrolyzing activity by Ermakov, E, Smirnova, L, Sinyanskii, L, Dobrygina, D, Semke, A, Nevinsky, G, Buneva, V, Ivanova, S

“…Introduction Autoantibodies (Abs) to different neuronal receptors and DNA were detected in the blood of patients with schizophrenia. Abs hydrolyzing DNA were…”
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Main factors providing specificity of repair enzymes by Nevinsky, G. A

“…Specific and nonspecific DNA complex formation with human uracil-DNA glycosylase, 8-oxoguanine-DNA glycosylase, and apurine/apyrimidine endonuclease, as well…”
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Natural antibodies to nucleic acids by Buneva, V. N., Krasnorutskii, M. A., Nevinsky, G. A.

“…Blood of healthy donors contains low concentrations of autoantibodies to its own components, including DNA and RNA. Increased concentrations of antibodies to…”
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Level of blood cell-free circulating mitochondrial DNA as a novel biomarker of acute myocardial ischemia by Sudakov, N. P., Popkova, T. P., Katyshev, A. I., Goldberg, O. A., Nikiforov, S. B., Pushkarev, B. G., Klimenkov, I. V., Lepekhova, S. A., Apartsin, K. A., Nevinsky, G. A., Konstantinov, Yu. M.

“…Changes in the level of blood cell-free circulating mitochondrial DNA were examined during experimental adrenaline-induced myocardial injury in rats. The…”
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In vitro initial attachment of HIV-1 integrase to viral ends: control of the DNA specific interaction by the oligomerization state by Lesbats, P, Métifiot, M, Calmels, C, Baranova, S, Nevinsky, G, Andreola, M.L, Parissi, V

“…HIV-1 integrase (IN) oligomerization and DNA recognition are crucial steps for the subsequent events of the integration reaction. Recent advances described the…”
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DNase, RNase, and phosphatase activities of antibodies formed upon immunization by DNA, DNase I, and DNase II by Krasnorutskii, M. A., Buneva, V. N., Nevinsky, G. A.

“…Relative DNase, RNase (efficiency of hydrolysis of ribo- and deoxyribooligonucleotides (ON)), and phosphatase (removal of the ON 5′ terminal phosphate)…”
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Synthesis and cytotoxicity evaluation of polyfluorinated 1,4-naphthoquinones containing amino acid substituents by Troshkova, N.M., Goryunov, L.I., Shteingarts, V.D., Zakharova, O.D., Ovchinnikova, L.P., Nevinsky, G.A.

“…New conjugates of polyfluorinated 1,4-naphthoquinone core with amino acids and their derivatives have been synthesized and evaluated to be the efficient growth…”
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Features of hydrolysis of specific and nonspecific globular proteins and oligopeptides by antibodies against viral integrase from blood of HIV-infected patients by Odintsova, E. S., Dmitrenok, P. S., Baranova, S. V., Timofeeva, A. M., Buneva, V. N., Nevinsky, G. A.

“…It was shown previously that, as differentiated from canonical proteases, abzymes against myelin basic protein (MBP) from blood of patients with multiple…”
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Lactoferrin and its biological functions by Kanyshkova, T G, Buneva, V N, Nevinsky, G A

“…Lactoferrin, a component of mammalian milk, is a member of the transferrin family. These glycoproteins transfer Fe(3+) ions. Lactoferrin is a unique…”
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Peculiarities of abzymes from sera and milk of healthy donors and patients with autoimmune and viral diseases by Nevinsky, G. A., Buneva, V. N.

“…The detection of catalytic activity of antibodies is the earliest indicator of development of autoimmune diseases (AID). In early stages of AID, the repertoire…”
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Human deoxyribonucleases by Baranovskii, A G, Buneva, V N, Nevinsky, G A

“…Although mammalian deoxyribonucleases were discovered more than 60 years ago, interest in these enzymes is not weakening. During the last decade, intensive…”
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Antibodies against DNA hydrolyze DNA and RNA by Krasnorutskii, M. A, Buneva, V. N, Nevinsky, G. A

“…In this work, rabbits were immunized with a high polymer DNA complexed with methylated BSA (mBSA) and by mBSA. It is shown that electrophoretically homogeneous…”
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