Search Results - "Neves, Rui P L"

Generating human prostate cancer organoids from leukapheresis enriched circulating tumour cells by Mout, Lisanne, van Dessel, Lisanne F., Kraan, Jaco, de Jong, Anouk C., Neves, Rui P.L., Erkens-Schulze, Sigrun, Beaufort, Corine M., Sieuwerts, Anieta M., van Riet, Job, Woo, Thomas L.C., de Wit, Ronald, Sleijfer, Stefan, Hamberg, Paul, Sandberg, Yorick, te Boekhorst, Peter A.W., van de Werken, Harmen J.G., Martens, John W.M., Stoecklein, Nikolas H., van Weerden, Wytske M., Lolkema, Martijn P.

“…Circulating tumour cell (CTC)–derived organoids have the potential to provide a powerful tool for personalised cancer therapy but are restrained by low CTC…”
Get full text

Circulating Tumour Cell Release after Cement Augmentation of Vertebral Metastases by Mohme, Malte, Riethdorf, Sabine, Dreimann, Marc, Werner, Stefan, Maire, Cecile L., Joosse, Simon A., Bludau, Frederic, Mueller, Volkmar, Neves, Rui P. L., Stoecklein, Nikolas H., Lamszus, Katrin, Westphal, Manfred, Pantel, Klaus, Wikman, Harriet, Eicker, Sven O.

“…Cement augmentation via percutaneous vertebroplasty or kyphoplasty for treatment of spinal metastasis is a well-established treatment option. We assessed…”
Get full text

Diagnostic leukapheresis for CTC analysis in breast cancer patients: CTC frequency, clinical experiences and recommendations for standardized reporting by Fehm, Tanja N., Meier‐Stiegen, Franziska, Driemel, Christiane, Jäger, Bernadette, Reinhardt, Florian, Naskou, Johanna, Franken, André, Neubauer, Hans, Neves, Rui P.L., Dalum, Guus, Ruckhäberle, Eugen, Niederacher, Dieter, Rox, Jutta M., Fischer, Johannes C., Stoecklein, Nikolas H.

“…Diagnostic leukapheresis (DLA) is based on continuous centrifugation that collects mononuclear cells from peripheral blood with a density of 1.055–1.08 g/ml…”
Get full text

Circulating biomarkers for early detection and clinical management of colorectal cancer by Marcuello, María, Vymetalkova, Veronika, Neves, Rui P.L., Duran-Sanchon, Saray, Vedeld, Hege Marie, Tham, Emma, van Dalum, Guus, Flügen, Georg, Garcia-Barberan, Vanesa, Fijneman, Remond JA, Castells, Antoni, Vodicka, Pavel, Lind, Guro E., Stoecklein, Nikolas H., Heitzer, Ellen, Gironella, Meritxell

“…New non-invasive approaches that can complement and improve on current strategies for colorectal cancer (CRC) screening and management are urgently needed. A…”
Get full text

Proficiency Testing to Assess Technical Performance for CTC-Processing and Detection Methods in CANCER-ID by Neves, Rui P L, Ammerlaan, Wim, Andree, Kiki C, Bender, Sebastian, Cayrefourcq, Laure, Driemel, Christiane, Koch, Claudia, Luetke-Eversloh, Merlin Verena, Oulhen, Marianne, Rossi, Elisabetta, Alix-Panabières, Catherine, Betsou, Fay, Farace, Françoise, Riethdorf, Sabine, Schlange, Thomas, Wikman, Harriet, Zamarchi, Rita, Pantel, Klaus, Terstappen, Leon W M M, Stoecklein, Nikolas H

“…Abstract Background Multiple technologies are available for detection of circulating tumor cells (CTCs), but standards to evaluate their technical performance…”
Get full text

Editorial: Liquid biopsy: A tool for better understanding of the metastatic process ecosystem by Bocci, Matteo, Fabbri, Francesco, Neves, Rui P.L., Rossi, Elisabetta

Get full text

Ultra-sensitive CTC-based liquid biopsy for pancreatic cancer enabled by large blood volume analysis by Stoecklein, Nikolas H, Fluegen, Georg, Guglielmi, Rosa, Neves, Rui P L, Hackert, Thilo, Birgin, Emrullah, Cieslik, Stefan A, Sudarsanam, Monica, Driemel, Christiane, van Dalum, Guus, Franken, André, Niederacher, Dieter, Neubauer, Hans, Fehm, Tanja, Rox, Jutta M, Böhme, Petra, Häberle, Lena, Göring, Wolfgang, Esposito, Irene, Topp, Stefan A, Coumans, Frank A W, Weitz, Jürgen, Knoefel, Wolfram T, Fischer, Johannes C, Bork, Ulrich, Rahbari, Nuh N

“…The limited sensitivity of circulating tumor cell (CTC) detection in pancreatic adenocarcinoma (PDAC) stems from their extremely low concentration in the whole…”
Get full text

Clinical application of circulating tumor cells by Stoecklein, Nikolas H., Oles, Julia, Franken, Andre, Neubauer, Hans, Terstappen, Leon W.M.M., Neves, Rui P.L.

“…This narrative review aims to provide a comprehensive overview of the current state of circulating tumor cell (CTC) analysis and its clinical significance in…”
Get full text

Magnetic-Based Enrichment of Rare Cells from High Concentrated Blood Samples by Wu, Junhao, Raba, Katharina, Guglielmi, Rosa, Behrens, Bianca, Van Dalum, Guus, Flügen, Georg, Koch, Andreas, Patel, Suraj, Knoefel, Wolfram T, Stoecklein, Nikolas H, Neves, Rui P L

“…Here, we tested two magnetic-bead based systems for the enrichment and detection of rare tumor cells in concentrated blood products. For that, the defined…”
Get full text

Image-Based Identification and Genomic Analysis of Single Circulating Tumor Cells in High Grade Serous Ovarian Cancer Patients by Salmon, Carolin, Levermann, Janina, Neves, Rui P. L., Liffers, Sven-Thorsten, Kuhlmann, Jan Dominik, Buderath, Paul, Kimmig, Rainer, Kasimir-Bauer, Sabine

“…In Ovarian Cancer (OC), the analysis of single circulating tumor cells (sCTCs) might help to investigate genetic tumor evolution during the course of…”
Get full text

Characterization of DNA Methylation in Circulating Tumor Cells by Pixberg, Constantin F, Schulz, Wolfgang A, Stoecklein, Nikolas H, Neves, Rui P L

“…Epigenetics contributes to molecular mechanisms leading to tumor cell transformation and systemic progression of cancer. However, the dynamics of epigenetic…”
Get full text

Genomic high-resolution profiling of single CKpos/CD45neg flow-sorting purified circulating tumor cells from patients with metastatic breast cancer by Neves, Rui P L, Raba, Katharina, Schmidt, Oliver, Honisch, Ellen, Meier-Stiegen, Franziska, Behrens, Bianca, Möhlendick, Birte, Fehm, Tanja, Neubauer, Hans, Klein, Christoph A, Polzer, Bernhard, Sproll, Christoph, Fischer, Johannes C, Niederacher, Dieter, Stoecklein, Nikolas H

“…Circulating tumor cells (CTCs) are promising surrogate markers for systemic disease, and their molecular characterization might be relevant to guide more…”
Get full text

Genomic High-Resolution Profiling of Single CK^sup pos^/CD45^sup neg^ Flow-Sorting Purified Circulating Tumor Cells from Patients with Metastatic Breast Cancer by Neves, Rui P L, Raba, Katharina, Schmidt, Oliver, Honisch, Ellen, Meier-Stiegen, Franziska, Behrens, Bianca, Möhlendick, Birte, Fehm, Tanja, Neubauer, Hans, Klein, Christoph A, Polzer, Bernhard, Sproll, Christoph, Fischer, Johannes C, Niederacher, Dieter, Stoecklein, Nikolas H

“…Circulating tumor cells (CTCs) are promising surrogate markers for systemic disease, and their molecular characterization might be relevant to guide more…”
Get full text

Abstract 4579: The genetic heterogeneity and the molecular evolution of systemic metastatic castration resistant prostate cancer during therapy by Neves, Rui PL, Anna, Streit LRF, Raba, Katharina, Bongers, Elina-Katharina, Behrens, Bianca, Dalum, Guus van, Flohr, Penny, Mateo, Joaquin, Sumanasuriya, Semini, Crespo, Mateus, Ebbs, Berni, Fowler, Gemma, Rescigno, Pasquale, Carreira, Suzanne, Lambros, Maryou, Petrini, Edoardo, Garonzi, Marianna, Manaresi, Nicolò, Bono, Johann de, Stoecklein, Nikolas H.

“…Abstract Background: Circulating tumour cells (CTCs) have a significant prognostic impact in metastatic castration-resistant prostate cancer (mCRPC) and…”
Get full text