Search Results - "Neurotoxicology and teratology"

Toxicity profiling of flame retardants in zebrafish embryos using a battery of assays for developmental toxicity, neurotoxicity, cardiotoxicity and hepatotoxicity toward human relevance by Alzualde, Ainhoa, Behl, Mamta, Sipes, Nisha S., Hsieh, Jui-Hua, Alday, Aintzane, Tice, Raymond R., Paules, Richard S., Muriana, Arantza, Quevedo, Celia

“…Following the voluntary phase-out of brominated flame retardants (BFRs) due to their environmental persistence and toxicity, the organophosphorus flame…”
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Glyphosate based- herbicide exposure affects gut microbiota, anxiety and depression-like behaviors in mice by Aitbali, Yassine, Ba-M'hamed, Saadia, Elhidar, Najoua, Nafis, Ahmed, Soraa, Nabila, Bennis, Mohamed

“…Recently, a number of studies have demonstrated the profound relationship between gut microbiota (GM) alterations and behavioral changes. Glyphosate-based…”
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Sources, occurrence and toxic effects of emerging per- and polyfluoroalkyl substances (PFAS) by Manojkumar, Y., Pilli, Sridhar, Rao, P. Venkateswara, Tyagi, Rajeshwar Dayal

“…Per- and polyfluoroalkyl substances (PFAS) cause potential threats to biota and are persistent and never-ending substances in the environment. Regulations and…”
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Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity by Behl, Mamta, Hsieh, Jui-Hua, Shafer, Timothy J, Mundy, William R, Rice, Julie R, Boyd, Windy A, Freedman, Jonathan H, Hunter, E. Sidney, Jarema, Kimberly A, Padilla, Stephanie, Tice, Raymond R

“…Abstract Due to their toxicity and persistence in the environment, brominated flame retardants (BFRs) are being phased out of commercial use, leading to the…”
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In utero exposure to valproic acid and autism — A current review of clinical and animal studies by Roullet, Florence I, Lai, Jonathan K.Y, Foster, Jane A

“…Abstract Valproic acid (VPA) is both an anti-convulsant and a mood stabilizer. Clinical studies over the past 40 years have shown that exposure to VPA in utero…”
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Do anesthetics harm the developing human brain? An integrative analysis of animal and human studies by Lin, Erica P., MD, Lee, Jeong-Rim, MD, PhD, Lee, Christopher S., MD, Deng, Meng, MD, PhD, Loepke, Andreas W., MD, PhD

“…Abstract Anesthetics permit surgical procedures and stressful interventions have been found to cause structural brain abnormalities and functional impairment…”
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Acute and developmental behavioral effects of flame retardants and related chemicals in zebrafish by Jarema, Kimberly A, Hunter, Deborah L, Shaffer, Rachel M, Behl, Mamta, Padilla, Stephanie

“…Abstract As polybrominated diphenyl ethers are phased out, numerous compounds are emerging as potential replacement flame retardants for use in consumer and…”
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Experience during adolescence shapes brain development: From synapses and networks to normal and pathological behavior by Dow-Edwards, Diana, MacMaster, Frank P., Peterson, Bradley S., Niesink, Raymond, Andersen, Susan, Braams, B.R.

“…Adolescence is a period of dramatic neural reorganization creating a period of vulnerability and the possibility for the development of psychopathology. The…”
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Neuroprotection and neurotoxicity in the developing brain: an update on the effects of dexmedetomidine and xenon by Alam, Azeem, Suen, Ka Chun, Hana, Zac, Sanders, Robert D, Maze, Mervyn, Ma, Daqing

“…Abstract Growing and consistent preclinical evidence, combined with early clinical epidemiological observations, suggest potentially neurotoxic effects of…”
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Effects of pyrethroids on brain development and behavior: Deltamethrin by Pitzer, Emily M., Williams, Michael T., Vorhees, Charles V.

“…Deltamethrin (DLM) is a Type II pyrethroid pesticide widely used in agriculture, homes, public spaces, and medicine. Epidemiological studies report that…”
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Ketamine anesthesia during the first week of life can cause long-lasting cognitive deficits in rhesus monkeys by Paule, M.G, Li, M, Allen, R.R, Liu, F, Zou, X, Hotchkiss, C, Hanig, J.P, Patterson, T.A, Slikker,, W, Wang, C

“…Abstract Previously our laboratory has shown that ketamine exposure (24 h of clinically relevant anesthesia) causes significant increases in neuronal cell…”
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Sub-lethal effects of the triazole fungicide propiconazole on zebrafish (Danio rerio) development, oxidative respiration, and larval locomotor activity by Souders, Christopher L., Xavier, Priscilla, Perez-Rodriguez, Veronica, Ector, Naomi, Zhang, Ji-Liang, Martyniuk, Christopher J.

“…Propiconazole is a triazole fungicide used in agriculture. Via run-off, it can enter the aquatic environment, and can adversely affect organisms. However, data…”
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Statistical modeling with litter as a random effect in mixed models to manage “intralitter likeness” by Golub, Mari S., Sobin, Christina A.

“…“Intralitter likeness,” the possibility that the shared genetics and/or maternal environment in multiparous species causes strong similarity for outcome…”
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Developmental exposure of zebrafish larvae to organophosphate flame retardants causes neurotoxicity by Sun, Liwei, Xu, Wenbin, Peng, Tao, Chen, Haigang, Ren, Lin, Tan, Hana, Xiao, Dan, Qian, Haifeng, Fu, Zhengwei

“…Abstract With the gradual ban on brominated flame retardants (FRs), the application of organophosphate flame retardants (OPFRs) has increased remarkably…”
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Embryonic exposure to cadmium (II) and chromium (VI) induce behavioral alterations, oxidative stress and immunotoxicity in zebrafish ( Danio rerio ) by Jin, Yuanxiang, Liu, Zhenzhen, Liu, Fang, Ye, Yang, Peng, Tao, Fu, Zhengwei

“…Abstract Cadmium (Cd) and chromium (Cr) are considered as the main environmental contaminants which have serious risks for health. Firstly, we observed that…”
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Paternal THC exposure in rats causes long-lasting neurobehavioral effects in the offspring by Levin, Edward D., Hawkey, Andrew B., Hall, Brandon J., Cauley, Marty, Slade, Susan, Yazdani, Elisa, Kenou, Bruny, White, Hannah, Wells, Corinne, Rezvani, Amir H., Murphy, Susan K.

“…Developmental neurotoxicity of a wide variety of toxicants mediated via maternal exposure during gestation is very well established. In contrast, the impacts…”
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Cytokine dysregulation in autism spectrum disorders (ASD): Possible role of the environment by Goines, Paula E, Ashwood, Paul

“…Abstract Autism spectrum disorders (ASD) are neurodevelopmental diseases that affect an alarming number of individuals. The etiological basis of ASD is…”
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Neuropsychological functioning in military pesticide applicators from the Gulf War: Effects on information processing speed, attention and visual memory by Sullivan, Kimberly, Krengel, Maxine, Bradford, William, Stone, Callie, Thompson, Terri Ann, Heeren, Timothy, White, Roberta F.

“…1991 Gulf War (GW) veterans continue to experience debilitating cognitive and mood problems more than two decades following their return from deployment…”
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Neurobehavioral impairments caused by developmental imidacloprid exposure in zebrafish by Crosby, Emily B, Bailey, Jordan M, Oliveri, Anthony N, Levin, Edward D

“…Abstract Background Neonicotinoid insecticides are becoming more widely applied as organophosphate (OP) insecticides are decreasing in use. Because of their…”
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Varying the exposure period and duration of neuroactive pharmaceuticals and their metabolites modulates effects on the visual motor response in zebrafish (Danio rerio) larvae by Huang, Irvin J., Sirotkin, Howard I., McElroy, Anne E.

“…Pharmaceuticals and personal care products are emerging contaminants that are increasingly detected in surface waters around the world. Despite the rise in…”
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