Search Results - "Neuroscience research"

Astrocyte reactivity and astrogliosis after spinal cord injury by Okada, Seiji, Hara, Masamitsu, Kobayakawa, Kazu, Matsumoto, Yoshihiro, Nakashima, Yasuharu

“…•Glial scars form through the reactive response of astrocytes after CNS injury.•Glial scars serve as a major barrier to regenerating axons and impair the…”
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The interaction of circRNAs and RNA binding proteins: An important part of circRNA maintenance and function by Zang, Jiankun, Lu, Dan, Xu, Anding

“…The widespread expression of circular RNAs (circRNAs) is regarded as a feature of gene expression in highly diverged eukaryotes. Recent studies have shown that…”
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Gender inequality in academia: Problems and solutions for women faculty in STEM by Casad, Bettina J., Franks, Jillian E., Garasky, Christina E., Kittleman, Melinda M., Roesler, Alanna C., Hall, Deidre Y., Petzel, Zachary W.

“…Recently there is widespread interest in women's underrepresentation in science, technology, engineering, and mathematics (STEM); however, progress toward…”
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Neuroinflammation: the role and consequences by Lyman, Monty, Lloyd, Dafydd G, Ji, Xunming, Vizcaychipi, Marcela P, Ma, Daqing

“…Neuroinflammation is central to the common pathology of several acute and chronic brain diseases. This review examines the consequences of excessive and…”
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The role of inflammation and the gut microbiome in depression and anxiety by Peirce, Jason M., Alviña, Karina

“…The study of the gut microbiome has increasingly revealed an important role in modulating brain function and mental health. In this review, we underscore…”
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Glia as sculptors of synaptic plasticity by Sancho, Laura, Contreras, Minerva, Allen, Nicola J.

“…•Non-neuronal glial cells regulate synaptic plasticity through multiple mechanisms.•Astrocytes and microglia regulate synapse number, function and…”
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The multi-dimensional roles of astrocytes in ALS by Yamanaka, Koji, Komine, Okiru

“…•Neurodegeneration in ALS is partly mediated by non-cell autonomous mechanism.•Astrocytes in ALS lose neuroprotective property and acquire toxic…”
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Understanding the broad influence of sex hormones and sex differences in the brain by McEwen, Bruce S., Milner, Teresa A.

“…Sex hormones act throughout the entire brain of both males and females via both genomic and nongenomic receptors. Sex hormones can act through many cellular…”
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Sex differences, gender and addiction by Becker, Jill B., McClellan, Michele L., Reed, Beth Glover

“…This review discusses alcohol and other forms of drug addiction as both a sociocultural and biological phenomenon. Sex differences and gender are not solely…”
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Neuroinflammation and blood–brain barrier disruption following traumatic brain injury: Pathophysiology and potential therapeutic targets by Sulhan, Suraj, Lyon, Kristopher A., Shapiro, Lee A., Huang, Jason H.

“…Traumatic Brain Injury (TBI) is the most frequent cause of death and disability in young adults and children in the developed world, occurring in over 1.7…”
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The PINK1–Parkin axis: An Overview by Tanaka, Keiji

“…•PINK1 is a mitochondrially localized Ser/Thr protein kinase.•Parkin is a RBR (RING-between-RING) type of ubiquitin ligase.•PINK1 and Parkin are responsible…”
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Cerebral hypoperfusion and glucose hypometabolism: Key pathophysiological modulators promote neurodegeneration, cognitive impairment, and Alzheimer's disease by Daulatzai, Mak Adam

“…Aging, hypertension, diabetes, hypoxia/obstructive sleep apnea (OSA), obesity, vitamin B12/folate deficiency, depression, and traumatic brain injury…”
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The placenta‐brain‐axis by Rosenfeld, Cheryl S.

“…All mammalian species depend on the placenta, a transient organ, for exchange of gases, nutrients, and waste between the mother and conceptus. Besides serving…”
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Pathology and mechanisms of cochlear aging by Keithley, Elizabeth M.

“…Presbycusis, or age‐related hearing loss (ARHL), occurs in most mammals with variations in the age of onset, rate of decline, and magnitude of degeneration in…”
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Sex Differences in Pain by Sorge, Robert E., Totsch, Stacie K.

“…Females greatly outnumber males as sufferers of chronic pain. Although social and psychological factors certainly play a role in the differences in prevalence…”
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Mitochondrial biogenesis in neurodegeneration by Li, P. Andy, Hou, Xiaolin, Hao, Shaocai

“…Mitochondria play a key role in energy production, calcium homeostasis, cell survival, and death. Adverse stimulations including neurodegenerative diseases may…”
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Reactive astrocytes in Alzheimer’s disease: A double-edged sword by Chun, Heejung, Lee, C. Justin

“…•The inflammatory features of Alzheimer’s disease(AD) are extensively reviewed.•Reactive astrocytes are not only an early sign for AD but also an initiator of…”
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Sex and the development of Alzheimer's disease by Pike, Christian J.

“…Men and women exhibit differences in the development and progression of Alzheimer's disease (AD). The factors underlying the sex differences in AD are not well…”
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Peripheral nerve injury and myelination: Potential therapeutic strategies by Modrak, Max, Talukder, M. A. Hassan, Gurgenashvili, Khatuna, Noble, Mark, Elfar, John C.

“…Traumatic peripheral nerve injury represents a major clinical and public health problem that often leads to significant functional impairment and permanent…”
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Comparative analyses of adeno-associated viral vector serotypes 1, 2, 5, 8 and 9 in marmoset, mouse and macaque cerebral cortex by Watakabe, Akiya, Ohtsuka, Masanari, Kinoshita, Masaharu, Takaji, Masafumi, Isa, Kaoru, Mizukami, Hiroaki, Ozawa, Keiya, Isa, Tadashi, Yamamori, Tetsuo

“…Here we investigated the transduction characteristics of adeno-associated viral vector (AAV) serotypes 1, 2, 5, 8 and 9 in the marmoset cerebral cortex. Using…”
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