Search Results - "Neumann, R.D"

Microarray analysis of differentially expressed genes after exposure of normal human fibroblasts to ionizing radiation from an external source and from DNA-incorporated iodine-125 radionuclide by Sokolov, M.V., Smirnova, N.A., Camerini-Otero, R.D., Neumann, R.D., Panyutin, I.G.

“…Exposure of cells to ionizing radiation (IR) produces changes in the expression level of a large number of genes. However, less is known of gene-expression…”
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392 POSTER Influence of wortmannin on non-homologous DNA end joining in human normal and cancer cells by Pastwa, E, Neumann, R.D, Winters, T.A

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Radiotoxicity of Iodine-125-Labeled Oligodeoxyribonucleotides in Mammalian Cells by Sedelnikova, Olga A, Panyutin, Igor G, Thierry, Alain R, Neumann, Ronald D

“…We investigated the distribution, stability and radiotoxicity of 125I-oligodeoxyribonucleotides (125I-ODN) in human fibrosarcoma HT-1080 cells to study the…”
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A Malignant Melanoma Imaging Agent: Synthesis, Characterization, In Vitro Binding and Biodistribution of Iodine-125-(2-Piperidinylaminoethyl)4-Iodobenzamide by John, C.S, Bowen, W.D, Saga, T, Kinuya, S, Vilner, B.J, Baumgold, J, Paik, C.H, Reba, R.C, Neumann, R.D, Varma, V.M, McAfee, J.G

“…In order to develop improved radiopharmaceuticals for imaging malignant melanoma, we have synthesized and characterized 125I-and 131I-labeled…”
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Ultrastructure and mineral composition of urinary calculi from horses by Neumann, R D, Ruby, A L, Ling, G V, Schiffman, P, Johnson, D L

“…Urinary calculi from 17 horses with urolithiasis were examined to study their mineral content and ultrastructure. Among the analytic methods used were X-ray…”
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The Cytotoxicity of Decays of Tritium and Iodine-125 Incorporated in DNA of Mammalian Cells. Implications for the Low-LET Dosimetry of Incorporated Nuclides by Geselowitz, Daniel A., McManaway, Mary E., Hofer, Kurt G., Neumann, Ronald D.

“…To quantify the toxicity of low-LET radiation from incorporated radionuclides, we have determined the toxicity of decays of [3 H]dThd pulse-incorporated into…”
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Ultrastructure of selected struvite-containing urinary calculi from cats by Neumann, R D, Ruby, A L, Ling, G V, Schiffman, P S, Johnson, D L

“…To elucidate the ultrastructural details of struvite-containing urinary calculi from cats. Specimens studied were inclusive of the range of textures visible…”
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In Vitro Complex Formation and Biodistribution of Mouse Antitumor Monoclonal Antibody in Cancer Patients by Sakahara, Harumi, Reynolds, James C, Carrasquillo, Jorge A, Lora, Margarita E, Maloney, Patrick J, Lotze, Michael T, Larson, Steven M, Neumann, Ronald D

“…The serum clearance and biodistribution of a murine monoclonal antibody were compared to the in vitro complex formation of the antibody with patients' sera…”
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Local distribution and concentration of intravenously injected sup 131 I-9. 2. 27 monoclonal antibody in human malignant melanoma by Del Vecchio, S., Reynolds, J.C., Carrasquillo, J.A., Blasberg, R.G., Neumann, R.D., Lotze, M.T., Bryant, G.J., Farkas, R.J., Larson, S.M.

“…Regional measurements of {sup 131}I-9.2.27 distribution in human melanoma tumors were obtained using quantitative autoradiography. Tumors were removed from…”
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Radiolabeled products in rat liver and serum after administration of antibody-amide-DTPA-indium-111 by Paik, C H, Sood, V K, Le, N, Cioloca, L, Carrasquillo, J A, Reynolds, J C, Neumann, R D, Reba, R C

“…Anti-human serum albumin antibody (Ab) was used as a model antibody. Ab was conjugated with DTPA using cyclic DTPA dianhydride reaction and radiolabeled with…”
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The ultrapurification of indium-111 for radiotracer studies by Zoghbi, S S, Neumann, R D, Gottschalk, A

“…We have developed a procedure for the ultrapurification of 111In. A dried sample of 111InCl3 is dissolved in 1 ml of a freshly prepared KI solution of 4% in 4…”
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Perfusion of nonventilated lung: failure of hypoxic vasoconstriction? by Sostman, H D, Neumann, R D, Gottschalk, A, Greenspan, R H

“…Alveolar hypoxia is a well established cause of regional vasoconstriction such that nonventilated segments are not perfused. The paradoxical situation of…”
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Preparation and immunoreactivity of high specific activity indium-111-DTPA labeled monoclonal antibody (MoAb) using ultrapure indium-111 by Zoghbi, S S, Neumann, R D, Gottschalk, A

“…The preparation of high-specific activity 111In-DTPA-MoAb without increasing the number of DTPA molecules per Ab was investigated. Instant thin layer…”
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The wind tunnel test 'system' of 1995; cost effective experimentation through a fusion of related technologies by Neumann, R.D., Webster, L.

“…A technology that allows the application of microfabrication techniques to wind tunnel experimentation is an onboard data acquisition system, the modular data…”
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Ultrasonography and hepatobiliary scintigraphy in the assessment of biliary-enteric anastomoses by Zeman, R K, Lee, C, Stahl, R S, Cahow, C E, Viscomi, G N, Neumann, R D, Gold, J A, Burrell, M I

“…Twenty-three patients with surgical diversion of the biliary tract were serially studied with ultrasonography and hepatobiliary scintigraphy using 99mTc-HIDA…”
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The influence of heparin on the in vivo distribution of IN-111 labeled platelets by Zoghbi, S S, Thakur, M L, Sostman, H D, Neumann, R D, Carbo, P, Lord, P, Greenspan, R H, Gottschalk, A

“…We investigated the influence of heparin (H) (bolus i.v.; 100-200 I.U./kg.) on the in vivo distribution and accumulation of autologous indium-111-platelets…”
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Intrapatient and interpatient comparison of tumor size and monoclonal antibody uptake in melanoma by Cornelius, E A, Neumann, R D, Zoghbi, S S, Kirkwood, J M, Ernstoff, M S, Unger, M M

“…In two panels totaling 52 patients with melanoma who were imaged with In-111 labeled 96.5 or ZME-018 (ZME) monoclonal antibodies (MoAb), four patients…”
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Platelet kinetics and biodistribution in canine endotoxemia by Sostman, H D, Zoghbi, S S, Smith, G J, Carbo, P, Neumann, R D, Gottschalk, A, Greenspan, R H

“…Kinetics and magnitudes of changes in Indium-labeled platelet biodistribution were studied in dogs given E. coli endotoxin. Marked, reversible, dose-dependent…”
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Monoclonal antibodies for radioimmunoscintigraphy of breast cancer by Merino, M J, Monteagudo, C, Neumann, R D

“…Breast cancer is the leading cause of cancer deaths among females, and it is estimated that each year, one in ten American women will be newly diagnosed as…”
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Evaluation of cardiovascular function in small animals using a microcomputer-based scintigraphic imaging system by Green, M.V., Andrich, M.P., Doudet, D., Markowitz, A., Tedder, T.E., Owens, E.S., Chaparro, M.I., Neumann, R.D.

“…The authors have devised a scintigraphic imaging system for evaluating cardiovascular structure and function in small animals. The system consists of an…”
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