Search Results - "Neumann, Jan Oliver"

Oncolytic H-1 Parvovirus Shows Safety and Signs of Immunogenic Activity in a First Phase I/IIa Glioblastoma Trial by Geletneky, Karsten, Hajda, Jacek, Angelova, Assia L., Leuchs, Barbara, Capper, David, Bartsch, Andreas J., Neumann, Jan-Oliver, Schöning, Tilman, Hüsing, Johannes, Beelte, Birgit, Kiprianova, Irina, Roscher, Mandy, Bhat, Rauf, von Deimling, Andreas, Brück, Wolfgang, Just, Alexandra, Frehtman, Veronika, Löbhard, Stephanie, Terletskaia-Ladwig, Elena, Fry, Jeremy, Jochims, Karin, Daniel, Volker, Krebs, Ottheinz, Dahm, Michael, Huber, Bernard, Unterberg, Andreas, Rommelaere, Jean

“…Oncolytic virotherapy may be a means of improving the dismal prognosis of malignant brain tumors. The rat H-1 parvovirus (H-1PV) suppresses tumors in…”
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Optimal Cerebral Perfusion Pressure: Targeted Treatment for Severe Traumatic Brain Injury by Petkus, Vytautas, Preiksaitis, Aidanas, Chaleckas, Edvinas, Chomskis, Romanas, Zubaviciute, Erika, Vosylius, Saulius, Rocka, Saulius, Rastenyte, Daiva, Aries, Marcel J, Ragauskas, Arminas, Neumann, Jan-Oliver

“…Identification of individual therapy targets is critical for traumatic brain injury (TBI) patients. Clinical outcomes depend on cerebrovascular autoregulation…”
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Tumor Infiltration in Enhancing and Non-Enhancing Parts of Glioblastoma: A Correlation with Histopathology by Eidel, Oliver, Burth, Sina, Neumann, Jan-Oliver, Kieslich, Pascal J, Sahm, Felix, Jungk, Christine, Kickingereder, Philipp, Bickelhaupt, Sebastian, Mundiyanapurath, Sibu, Bäumer, Philipp, Wick, Wolfgang, Schlemmer, Heinz-Peter, Kiening, Karl, Unterberg, Andreas, Bendszus, Martin, Radbruch, Alexander

“…To correlate histopathologic findings from biopsy specimens with their corresponding location within enhancing areas, non-enhancing areas and necrotic areas on…”
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Frame-based stereotactic biopsies using an intraoperative MR-scanner are as safe and effective as conventional stereotactic procedures by Neumann, Jan-Oliver, Campos, Benito, Younes, Bilal, Jakobs, Martin, Jungk, Christine, Beynon, Christopher, Deimling, Andreas von, Unterberg, Andreas, Kiening, Karl

“…Frame-based stereotactic biopsy (FBSB) is a minimally-invasive and effective procedure for the diagnosis of brain lesions and will likely gain clinical…”
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Automatic Analysis of Cellularity in Glioblastoma and Correlation with ADC Using Trajectory Analysis and Automatic Nuclei Counting by Eidel, Oliver, Neumann, Jan-Oliver, Burth, Sina, Kieslich, Pascal J, Jungk, Christine, Sahm, Felix, Kickingereder, Philipp, Kiening, Karl, Unterberg, Andreas, Wick, Wolfgang, Schlemmer, Heinz-Peter, Bendszus, Martin, Radbruch, Alexander

“…Several studies have analyzed a correlation between the apparent diffusion coefficient (ADC) derived from diffusion-weighted MRI and the tumor cellularity of…”
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Automatic Planning Tools for Lumbar Pedicle Screws: Comparison and Validation of Planning Accuracy for Self-Derived Deep-Learning-Based and Commercial Atlas-Based Approaches by Scherer, Moritz, Kausch, Lisa, Bajwa, Akbar, Neumann, Jan-Oliver, Ishak, Basem, Naser, Paul, Vollmuth, Philipp, Kiening, Karl, Maier-Hein, Klaus, Unterberg, Andreas

“…This ex vivo experimental study sought to compare screw planning accuracy of a self-derived deep-learning-based (DL) and a commercial atlas-based (ATL) tool…”
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Spinal oncologic paraparesis: Analysis of neurological and surgical outcomes in patients with intramedullary, extramedullary, and extradural tumors by Alhalabi, Obada T, Heene, Stefan, Landré, Vincent, Neumann, Jan-Oliver, Scherer, Moritz, Ishak, Basem, Kiening, Karl, Zweckberger, Klaus, Unterberg, Andreas W, Younsi, Alexander

“…Paraparesis due to oncologic lesions of the spine warrants swift neurosurgical intervention to prevent permanent disability and hence maintain independence of…”
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Feasibility of Fluid Responsiveness Assessment in Patients at Risk for Increased Intracranial Pressure by Zivkovic, Aleksandar R, Kjaev, Aleko, Schönenberger, Silvia, Krieg, Sandro M, Weigand, Markus A, Neumann, Jan-Oliver

“…Effective fluid management is important for patients at risk of increased intracranial pressure (ICP). Maintaining constant cerebral perfusion represents a…”
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Anterior Access to the Cervicothoracic Junction via Partial Sternotomy: A Clinical Series Reporting on Technical Feasibility, Postoperative Morbidity, and Early Surgical Outcome by Issa, Mohammed, Neumann, Jan-Oliver, Al-Maisary, Sameer, Dyckhoff, Gerhard, Kronlage, Moritz, Kiening, Karl L, Ishak, Basem, Unterberg, Andreas W, Scherer, Moritz

“…Surgical access to the cervicothoracic junction (CTJ) is challenging. The aim of this study was to assess technical feasibility, early morbidity, and outcome…”
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Nuclear Overhauser Enhancement imaging of glioblastoma at 7 Tesla: region specific correlation with apparent diffusion coefficient and histology by Paech, Daniel, Burth, Sina, Windschuh, Johannes, Meissner, Jan-Eric, Zaiss, Moritz, Eidel, Oliver, Kickingereder, Philipp, Nowosielski, Martha, Wiestler, Benedikt, Sahm, Felix, Floca, Ralf Omar, Neumann, Jan-Oliver, Wick, Wolfgang, Heiland, Sabine, Bendszus, Martin, Schlemmer, Heinz-Peter, Ladd, Mark Edward, Bachert, Peter, Radbruch, Alexander

“…To explore the correlation between Nuclear Overhauser Enhancement (NOE)-mediated signals and tumor cellularity in glioblastoma utilizing the apparent diffusion…”
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Deep learning aided preoperative diagnosis of primary central nervous system lymphoma by Naser, Paul Vincent, Maurer, Miriam Cindy, Fischer, Maximilian, Karimian-Jazi, Kianush, Ben-Salah, Chiraz, Bajwa, Awais Akbar, Jakobs, Martin, Jungk, Christine, Jesser, Jessica, Bendszus, Martin, Maier-Hein, Klaus, Krieg, Sandro M., Neher, Peter, Neumann, Jan-Oliver

“…The preoperative distinction between glioblastoma (GBM) and primary central nervous system lymphoma (PCNSL) can be difficult, even for experts, but is highly…”
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MR Angiography at 7T to Visualize Cerebrovascular Territories by Neumann, Jan-Oliver, Giese, Henrik, Nagel, Armin M., Biller, Armin, Unterberg, Andreas, Meinzer, Hans-Peter

“…ABSTRACT BACKGROUND There is considerable amount of interindividual variability in the size and location of the vascular territories of the major brain…”
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Evaluation of a Novel Brain Tissue Oxygenation Probe in an Experimental Swine Model by Orakcioglu, Berk, Sakowitz, Oliver W, Neumann, Jan-Oliver, Kentar, Modar M, Unterberg, Andreas, Kiening, Karl L

“…Abstract BACKGROUND: Cerebral microdialysis, cerebral blood flow, and cerebral oxygenation (PbrO2) measurements using intraparenchymal probes are widely…”
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Stereotactic frame-based biopsy of infratentorial lesions via the suboccipital-transcerebellar approach with the Zamorano-Duchovny stereotactic system—a retrospective analysis of 79 consecutive cases by Kaes, Manuel, Beynon, Christopher, Kiening, Karl, Neumann, Jan-Oliver, Jakobs, Martin

“…Objective Lesions of the posterior fossa (brainstem and cerebellum) are challenging in diagnosis and treatment due to the fact that they are often located…”
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Routine ICU admission after brain tumor surgery: retrospective validation and critical appraisal of two prediction scores by Neumann, Jan-Oliver, Schmidt, Stephanie, Nohman, Amin, Jakobs, Martin, Unterberg, Andreas

“…Background Routine admission to an intensive care unit (ICU) following brain tumor surgery has been a common practice for many years. Although this practice…”
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Stereotactic Biopsy and Drainage of a Brainstem Abscess Caused by Listeria Monocytogenes: Case Report by BEYNON, Christopher, NEUMANN, Jan-Oliver, BÖSEL, Julian, UNTERBERG, Andreas W., KIENING, Karl L.

“…Listerial rhombencephalitis and brain abscesses are rare, but potentially life-threatening conditions. Early initiation of antibiotic therapy is crucial, but…”
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Stroke-Related Early Tracheostomy Versus Prolonged Orotracheal Intubation in Neurocritical Care Trial (SETPOINT): A Randomized Pilot Trial by BÖSEL, Julian, SCHILLER, Petra, HACKE, Werner, STEINER, Thorsten, HOOK, Yvonne, ANDES, Michaela, NEUMANN, Jan-Oliver, POLI, Sven, AMIRI, Hemasse, SCHÖNENBERGER, Silvia, ZHONGYING PENG, UNTERBERG, Andreas

“…Optimal timing of tracheostomy in ventilated patients with severe stroke is unclear. We aimed to investigate feasibility, safety, and potential advantages of…”
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Effect of Early vs Standard Approach to Tracheostomy on Functional Outcome at 6 Months Among Patients With Severe Stroke Receiving Mechanical Ventilation: The SETPOINT2 Randomized Clinical Trial by Bösel, Julian, Niesen, Wolf-Dirk, Salih, Farid, Morris, Nicholas A, Ragland, Jeremy T, Gough, Bryan, Schneider, Hauke, Neumann, Jan-Oliver, Hwang, David Y, Kantamneni, Phani, James, Michael L, Freeman, William D, Rajajee, Venkatakrishna, Rao, Chethan Venkatasubba, Nair, Deepak, Benner, Laura, Meis, Jan, Klose, Christina, Kieser, Meinhard, Suarez, José I, Schönenberger, Silvia, Seder, David B

“…IMPORTANCE: Many patients with severe stroke have impaired airway protective reflexes, resulting in prolonged invasive mechanical ventilation. OBJECTIVE: To…”
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Stereotactic biopsy and drainage of a brainstem abscess caused by Listeria monocytogenes by Beynon, Christopher, Neumann, Jan-Oliver, Bösel, Julian, Unterberg, Andreas W, Kiening, Karl L

“…Listerial rhombencephalitis and brain abscesses are rare, but potentially life-threatening conditions. Early initiation of antibiotic therapy is crucial, but…”
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The use of quantitative pupillometry in brain death determination: preliminary findings by Lenga, Pavlina, Kühlwein, Daniel, Schönenberger, Silvia, Neumann, Jan-Oliver, Unterberg, Andreas W., Beynon, Christopher

“…Purpose Quantitative pupillometry (QP) has been increasingly applied in neurocritical care as an easy-to-use and reliable technique for evaluating the…”
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