Search Results - "Neumann, Heinz"

Rewiring translation – Genetic code expansion and its applications by Neumann, Heinz

“…With few minor variations, the genetic code is universal to all forms of life on our planet. It is difficult to imagine that one day organisms might exist that…”
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The use of unnatural amino acids to study and engineer protein function by Neumann-Staubitz, Petra, Neumann, Heinz

“…[Display omitted] •Unnatural amino acids provide a plethora of novel functionalities to study protein function.•Crosslinker UAAs are being used to monitor…”
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Organelle size control - increasing vacuole content activates SNAREs to augment organelle volume through homotypic fusion by Desfougères, Yann, Neumann, Heinz, Mayer, Andreas

“…Cells control the size of their compartments relative to cell volume, but there is also size control within each organelle. Yeast vacuoles neither burst nor do…”
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A Cascade of Histone Modifications Induces Chromatin Condensation in Mitosis by Wilkins, Bryan J., Rall, Nils A., Ostwal, Yogesh, Kruitwagen, Tom, Hiragami-Hamada, Kyoko, Winkler, Marco, Barral, Yves, Fischle, Wolfgang, Neumann, Heinz

“…Metaphase chromosomes are visible hallmarks of mitosis, yet our understanding of their structure and of the forces shaping them is rudimentary. Phosphorylation…”
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In Vivo Mapping of FACT–Histone Interactions Identifies a Role of Pob3 C‑terminus in H2A–H2B Binding by Hoffmann, Christian, Neumann, Heinz

“…Histone chaperones assist nucleosomal rearrangements to facilitate the passage of DNA and RNA polymerases through chromatin. The FACT (facilitates chromatin…”
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A Method for Genetically Installing Site-Specific Acetylation in Recombinant Histones Defines the Effects of H3 K56 Acetylation by Neumann, Heinz, Hancock, Susan M., Buning, Ruth, Routh, Andrew, Chapman, Lynda, Somers, Joanna, Owen-Hughes, Tom, van Noort, John, Rhodes, Daniela, Chin, Jason W.

“…Lysine acetylation of histones defines the epigenetic status of human embryonic stem cells and orchestrates DNA replication, chromosome condensation,…”
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Genetic Encoding and Labeling of Aliphatic Azides and Alkynes in Recombinant Proteins via a Pyrrolysyl-tRNA Synthetase/tRNACUA Pair and Click Chemistry by Nguyen, Duy P, Lusic, Hrvoje, Neumann, Heinz, Kapadnis, Prashant B, Deiters, Alexander, Chin, Jason W

“…We demonstrate that an orthogonal Methanosarcina barkeri MS pyrrolysyl-tRNA synthetase/tRNACUA pair directs the efficient, site-specific incorporation of…”
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Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin by Hiragami-Hamada, Kyoko, Soeroes, Szabolcs, Nikolov, Miroslav, Wilkins, Bryan, Kreuz, Sarah, Chen, Carol, De La Rosa-Velázquez, Inti A., Zenn, Hans Michael, Kost, Nils, Pohl, Wiebke, Chernev, Aleksandar, Schwarzer, Dirk, Jenuwein, Thomas, Lorincz, Matthew, Zimmermann, Bastian, Walla, Peter Jomo, Neumann, Heinz, Baubec, Tuncay, Urlaub, Henning, Fischle, Wolfgang

“…Histone H3 trimethylation of lysine 9 (H3K9me3) and proteins of the heterochromatin protein 1 (HP1) family are hallmarks of heterochromatin, a state of…”
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Determination of Grain Growth Kinetics and Assessment of Welding Effect on Properties of S700MC Steel in the HAZ of Welded Joints by Moravec, Jaromir, Novakova, Iva, Sobotka, Jiri, Neumann, Heinz

“…The welding of fine-grained steels is a very specific technology because of the requirement for the heat input limit value. Applying temperature cycles results…”
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Catalytic Core of a Membrane-Associated Eukaryotic Polyphosphate Polymerase by Hothorn, Michael, Neumann, Heinz, Lenherr, Esther D, Wehner, Mark, Rybin, Vladimir, Hassa, Paul O, Uttenweiler, Andreas, Reinhardt, Monique, Schmidt, Andrea, Seiler, Jeanette, Ladurner, Andreas G, Herrmann, Christian, Scheffzek, Klaus, Mayer, Andreas

“…Polyphosphate (polyP) occurs ubiquitously in cells, but its functions are poorly understood and its synthesis has only been characterized in bacteria. Using…”
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Acetylation regulates Cyclophilin A catalysis, immunosuppression and HIV isomerization by Chin, Jason W, James, Leo C, Lammers, Michael, Neumann, Heinz

“…The detailed characterization of endogenous proteins and use of non-natural amino acid engineering allows the identification and structural and functional…”
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Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution by Gao, Mengqing, Wang, Jin, Rousseaux, Sophie, Tan, Minjia, Pan, Lulu, Peng, Lijun, Wang, Sisi, Xu, Wenqian, Ren, Jiayi, Liu, Yuanfang, Spinck, Martin, Barral, Sophie, Wang, Tao, Chuffart, Florent, Bourova-Flin, Ekaterina, Puthier, Denis, Curtet, Sandrine, Bargier, Lisa, Cheng, Zhongyi, Neumann, Heinz, Li, Jian, Zhao, Yingming, Mi, Jian-Qing, Khochbin, Saadi

“…In addition to acetylation, histones are modified by a series of competing longer-chain acylations. Most of these acylation marks are enriched and co-exist…”
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A method to map the interaction network of the nuclear lamina with genetically encoded photo-crosslinkers in vivo by Neumann-Staubitz, Petra, Kitsberg, Daniel, Buxboim, Amnon, Neumann, Heinz

“…Lamins are intermediate filaments that assemble in a meshwork at the inner nuclear periphery of metazoan cells. The nuclear periphery fulfils important…”
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Domestic mite antigens in floor and airborne dust at workplaces in comparison to living areas: a new immunoassay to assess personal airborne allergen exposure by Sander, Ingrid, Zahradnik, Eva, Kraus, Gerhard, Mayer, Stefan, Neumann, Heinz-Dieter, Fleischer, Christina, Brüning, Thomas, Raulf-Heimsoth, Monika

“…Allergens produced by domestic mites (DM) are among the most common allergic sensitizers and risk factors for asthma. To compare exposure levels between…”
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The vacuolar transporter chaperone (VTC) complex is required for microautophagy by Uttenweiler, Andreas, Schwarz, Heinz, Neumann, Heinz, Mayer, Andreas

“…Microautophagy involves direct invagination and fission of the vacuolar/lysosomal membrane under nutrient limitation. This occurs by an autophagic tube, a…”
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The H2B ubiquitin ligase RNF40 cooperates with SUPT16H to induce dynamic changes in chromatin structure during DNA double-strand break repair by Kari, Vijayalakshmi, Shchebet, Andrei, Neumann, Heinz, Johnsen, Steven A.

“…Many anticancer therapies function largely by inducing DNA double-strand breaks (DSBs) or altering the ability of cancer cells to repair them. Proper and…”
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De Novo Generation of Mutually Orthogonal Aminoacyl-tRNA Synthetase/tRNA Pairs by Neumann, Heinz, Slusarczyk, Adrian L, Chin, Jason W

“…The genetic code sets the correspondence between codons and the amino acids they encode in protein translation. The code is enforced by aminoacyl-tRNA…”
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Axial contraction and short-range compaction of chromatin synergistically promote mitotic chromosome condensation by Kruitwagen, Tom, Denoth-Lippuner, Annina, Wilkins, Bryan J, Neumann, Heinz, Barral, Yves

“…The segregation of eukaryotic chromosomes during mitosis requires their extensive folding into units of manageable size for the mitotic spindle. Here, we…”
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Allergen quantification in surface dust samples from German day care centers by Sander, Ingrid, Neumann, Heinz-Dieter, Lotz, Anne, Czibor, Christina, Zahradnik, Eva, Flagge, Angelika, Faller, Inga, Buxtrup, Martin, Brüning, Thomas, Raulf, Monika

“…Indoor allergens are among the main causes of allergic rhinitis and asthma. Allergen exposure is not limited to private homes. Mite, cat, and dog allergens…”
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Reliability and Correlation Between Indoor Allergen Concentrations from Vacuumed Surface Samples and Electrostatic Dust Collectors by Sander, Ingrid, Lotz, Anne, Neumann, Heinz-Dieter, Czibor, Christina, Zahradnik, Eva, Raulf, Monika

“…Most studies on indoor allergen exposure used vacuumed surface samples for quantification. One alternative is electrostatic dust collectors (EDCs), which…”
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