Search Results - "Neumann, Donna M"

Persistent HCMV infection of a glioblastoma cell line contributes to the development of resistance to temozolomide by Singh, Pankaj, Neumann, Donna M.

“…•Chronic HCMV infection led to increased cell proliferation and cell viability of LN 229 glioblastoma cells.•Chronic HCMV infection increased resistance to the…”
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CTCF Binding Sites in the Herpes Simplex Virus 1 Genome Display Site-Specific CTCF Occupation, Protein Recruitment, and Insulator Function by Washington, Shannan D, Musarrat, Farhana, Ertel, Monica K, Backes, Gregory L, Neumann, Donna M

“…There are seven conserved CTCF binding domains in the herpes simplex virus 1 (HSV-1) genome. These binding sites individually flank the latency-associated…”
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Synthesis and antifungal activity of substituted 2,4,6-pyrimidinetrione carbaldehyde hydrazones by Neumann, Donna M., Cammarata, Amy, Backes, Gregory, Palmer, Glen E., Jursic, Branko S.

“…Opportunistic fungal infections caused by the Candida spp. are the most common human fungal infections, often resulting in severe systemic infections—a…”
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HSV-1 infection of human brain cells induces miRNA-146a and Alzheimer-type inflammatory signaling by Hill, James M, Zhao, Yuhai, Clement, Christian, Neumann, Donna M, Lukiw, Walter J

“…Herpes simplex virus type-1 (HSV-1) infection of human brain cells induces changes in gene expression favorable to the propagation of the infecting agent and…”
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Deletion of the CTRL2 Insulator in HSV-1 Results in the Decreased Expression of Genes Involved in Axonal Transport and Attenuates Reactivation In Vivo by Singh, Pankaj, Collins, Matthew F, Johns, Richard N, Manuel, Kayley A, Ye, Ziyun A, Bloom, David C, Neumann, Donna M

“…HSV-1 is a human pathogen that establishes a lifelong infection in the host. HSV-1 is transported by retrograde axonal transport to sensory neurons in the…”
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CTCF Occupation of the Herpes Simplex Virus 1 Genome Is Disrupted at Early Times Postreactivation in a Transcription-Dependent Manner by ERTEL, Monica K, CAMMARATA, Amy L, HRON, Rebecca J, NEUMANN, Donna M

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Cohesin Subunit Rad21 Binds to the Herpes Simplex Virus 1 Genome near CTCF Insulator Sites during Latency In Vivo by Singh, Pankaj, Neumann, Donna M

“…Herpes simplex virus 1 (HSV-1) is a human pathogen that can establish a lifelong infection in the host. During latency, HSV-1 genomes are chromatinized and are…”
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Changes to euchromatin on LAT and ICP4 following reactivation are more prevalent in an efficiently reactivating strain of HSV-1 by Creech, Clinton C, Neumann, Donna M

“…Epigenetic mechanisms, via post-translational histone modifications, have roles in the establishment and maintenance of latency of the HSV-1 genome in the…”
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Host factors associated with either VP16 or VP16‐induced complex differentially affect HSV‐1 lytic infection by Ding, Xiuyan, Neumann, Donna M., Zhu, Liqian

“…Herpes simplex virus type 1 (HSV‐1) is an important human pathogen with neurotropism. Following lytic infection in mucosal or skin epithelium, life‐long…”
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In Vivo Changes in the Patterns of Chromatin Structure Associated with the Latent Herpes Simplex Virus Type 1 Genome in Mouse Trigeminal Ganglia Can Be Detected at Early Times after Butyrate Treatment by NEUMANN, Donna M, BHATTACHARJEE, Partha S, GIORDANI, Nicole V, BLOOM, David C, HILL, James M

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Cohesin subunit Rad21 binds to the HSV-1 genome near CTCF insulator sites during latency in vivo by Singh, Pankaj, Neumann, Donna M

“…Herpes Simplex Virus 1 (HSV-1) is a human pathogen that has the ability to establish a lifelong infection in the host. During latency, HSV-1 genomes are…”
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During Herpes Simplex Virus Type 1 Infection of Rabbits, the Ability To Express the Latency-Associated Transcript Increases Latent-Phase Transcription of Lytic Genes by GIORDANI, Nicole V, NEUMANN, Donna M, KWIATKOWSKI, Dacia L, BHATTACHARJEE, Partha S, MCANANY, Peterjon K, HILL, James M, BLOOM, David C

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The High Prevalence of Herpes Simplex Virus Type 1 DNA in Human Trigeminal Ganglia Is Not a Function of Age or Gender by HILL, James M, BALL, Melvyn J, KAUFMAN, Herbert E, THOMPSON, Hilary W, NEUMANN, Donna M, AZCUY, Ann M, BHATTACHARJEE, Partha S, BOUHANIK, Saadallah, CLEMENT, Christian, LUKIW, Walter J, FOSTER, Timothy P, KUMAR, Manish

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Synthesis and antifungal activity of substituted salicylaldehyde hydrazones, hydrazides and sulfohydrazides by Backes, Gregory L., Neumann, Donna M., Jursic, Branko S.

“…Efficient synthetic procedures for the preparation of acid hydrazines and hydrazides were developed by converting the corresponding carboxylic acid into the…”
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Sodium Butyrate: a Chemical Inducer of In Vivo Reactivation of Herpes Simplex Virus Type 1 in the Ocular Mouse Model by NEUMANN, Donna M, BHATTACHARJEE, Partha S, HILL, James M

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The HSV-1 encoded CCCTC-binding factor, CTRL2, impacts the nature of viral chromatin during HSV-1 lytic infection by Singh, Pankaj, Zhu, Liqian, Shipley, Mason A, Ye, Ziyun A, Neumann, Donna M

“…HSV-1 genomes are rapidly heterochromatinized following entry by host cells to limit viral gene expression. Efficient HSV-1 genome replication requires…”
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Herpes Simplex Virus 1 MicroRNA miR-H8 Is Dispensable for Latency and Reactivation In Vivo by Barrozo, Enrico R, Nakayama, Sanae, Singh, Pankaj, Neumann, Donna M, Bloom, David C

“…The regulatory functions of 10 individual viral microRNAs (miRNAs) that are abundantly expressed from the herpes simplex virus 1 (HSV-1) latency-associated…”
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A Human Apolipoprotein E Mimetic Peptide Effectively Inhibits HSV-1 TK-Positive and TK-Negative Acute Epithelial Keratitis in Rabbits by Bhattacharjee, Partha S., Neumann, Donna M., Hill, James M.

“…Purpose: To compare the antiviral effect of a peptide derived from human apolipoprotein E (1% apoEdp) with 1% trifluorothymidine against HSV-1 thymidine kinase…”
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Deletion of Herpes Simplex Virus 1 MicroRNAs miR-H1 and miR-H6 Impairs Reactivation by Barrozo, Enrico R, Nakayama, Sanae, Singh, Pankaj, Vanni, Emilia A H, Arvin, Ann M, Neumann, Donna M, Bloom, David C

“…During all stages of infection, herpes simplex virus 1 (HSV-1) expresses viral microRNAs (miRNAs). There are at least 20 confirmed HSV-1 miRNAs, yet the roles…”
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The CCCTC Binding Factor, CTRL2, Modulates Heterochromatin Deposition and the Establishment of Herpes Simplex Virus 1 Latency In Vivo by Washington, Shannan D, Singh, Pankaj, Johns, Richard N, Edwards, Terri G, Mariani, Michael, Frietze, Seth, Bloom, David C, Neumann, Donna M

“…The cellular insulator protein CTCF plays a role in herpes simplex virus 1 (HSV-1) latency through the establishment and regulation of chromatin boundaries. We…”
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