Search Results - "Neumann, Berit"
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Noncytolytic CD8+ Cell Mediated Antiviral Response Represents a Strong Element in the Immune Response of Simian Immunodeficiency Virus-Infected Long-Term Non-Progressing Rhesus Macaques
Published in PloS one (09-11-2015)“…The ability of long term non progressors to maintain very low levels of HIV/SIV and a healthy state, involves various host genetic and immunological factors…”
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Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity
Published in Nature communications (10-04-2018)“…HIV-1 causes chronic inflammation and AIDS in humans, whereas related simian immunodeficiency viruses (SIVs) replicate efficiently in their natural hosts…”
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IRF-1 Expression Is Essential for Natural Killer Cells to Suppress Metastasis
Published in Cancer research (Chicago, Ill.) (15-10-2011)“…IFN-γ promotes tumoral immune surveillance, but its involvement in controlling metastases is less clear. Using a mouse model of pulmonary metastases, we show…”
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Mesenchymal Stem Cell‐Dependent Formation of Heterotopic Tendon‐Bone Insertions (Osteotendinous Junctions)
Published in Stem cells (Dayton, Ohio) (01-09-2010)“…Ligament‐to‐bone and tendon‐to‐bone interfaces (entheses, osteotendinous junctions [OTJs]) serve to dissipate stress between soft tissue and bone. Surgical…”
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IRF-1 is critical for IFNγ mediated immune surveillance
Published in Oncoimmunology (01-07-2012)“…We recently described that IRF-1 is important for IFNγ mediated immune surveillance in metastasis. Despite the upregulation of MHC Class I in tumor cells,…”
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Comparative phenotypical analysis of B cells in fresh and cryopreserved mononuclear cells from blood and tissue of rhesus macaques
Published in Journal of immunological methods (01-06-2016)“…Cryopreservation of peripheral blood mononuclear cells (PBMCs) is common for large clinical trials for which phenotypical characterization of lymphocytes is…”
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Characterization of B and plasma cells in blood, bone marrow, and secondary lymphoid organs of rhesus macaques by multicolor flow cytometry
Published in Journal of leukocyte biology (01-01-2015)“…A comprehensive analysis of rhesus B cell subsets and plasma cells as a basis for studies on disease‐related B and plasma cell disorders. B cells, as an…”
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Noncytolytic CD8.sup.+ Cell Mediated Antiviral Response Represents a Strong Element in the Immune Response of Simian Immunodeficiency Virus-Infected Long-Term Non-Progressing Rhesus Macaques
Published in PloS one (09-11-2015)“…The ability of long term non progressors to maintain very low levels of HIV/SIV and a healthy state, involves various host genetic and immunological factors…”
Get full text
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Elevated granzyme B+ B‐cell level in SIV‐infection correlate with viral load and low CD4 T‐cell count
Published in Immunology and cell biology (01-03-2017)“…Granzyme B‐expressing (GrB+) B cells are thought to contribute to immune dysfunctions in HIV patients, but so far their exact role is unknown. This report…”
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OMIP‐026: Phenotypic analysis of B and plasma cells in rhesus macaques
Published in Cytometry. Part A (01-09-2015)Get full text
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Elevated granzyme B super(+) B-cell level in SIV-infection correlate with viral load and low CD4 T-cell count
Published in Immunology and cell biology (01-03-2017)“…Granzyme B-expressing (GrB super(+)) B cells are thought to contribute to immune dysfunctions in HIV patients, but so far their exact role is unknown. This…”
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Hepatitis C Virus Replication in Mouse Cells Is Restricted by IFN-Dependent and -Independent Mechanisms
Published in Gastroenterology (New York, N.Y. 1943) (01-12-2013)“…Background & Aims Current treatment strategies for hepatitis C virus (HCV) infection include pegylated interferon (IFN)-alfa and ribavirin. Approximately 50%…”
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Exclusive Decoration of Simian Immunodeficiency Virus Env with High-Mannose Type N-Glycans Is Not Compatible with Mucosal Transmission in Rhesus Macaques
Published in Journal of virology (01-11-2015)“…Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) envelope (Env) proteins are extensively decorated with N-glycans, predominantly of…”
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Comprehensive panel of cross-reacting monoclonal antibodies for analysis of different immune cells and their distribution in the common marmoset (Callithrix jacchus)
Published in Journal of medical primatology (01-06-2016)“…Background Common marmosets are extensively used in immunological and pharmacological research, and the usage of methods such as flow cytometry gain increasing…”
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Noncytolytic CD8+ Cell Mediated Antiviral Response Represents a Strong Element in the Immune Response of Simian Immunodeficiency Virus-Infected Long-Term Non-Progressing Rhesus Macaques: e0142086
Published in PloS one (01-11-2015)“…The ability of long term non progressors to maintain very low levels of HIV/SIV and a healthy state, involves various host genetic and immunological factors…”
Get full text
Journal Article -
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Long‐term efficient control of SIV infection in macaques is associated with an intact intestinal barrier
Published in Journal of medical primatology (01-08-2017)“…Hallmarks of SIV infection are early depletion of gut CD4 T cells and diminished intestinal integrity. Comprehensive studies on colon biopsies of SIV‐infected…”
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Frequencies of lymphoid T-follicular helper cells obtained longitudinally by lymph node fine-needle aspiration correlate significantly with viral load in SIV-infected rhesus monkeys
Published in Journal of medical primatology (01-10-2015)“…Background T‐follicular helper (TFH) cells are an important population in lymph nodes (LNs) contributing to the generation of highly specific B cells. For SIV…”
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PS2-078 Interferon Regulatory Factor-1 promotes NK cell-mediated suppression of lung metastasis through DNAM1/CD155 interaction
Published in Cytokine (Philadelphia, Pa.) (01-10-2011)Get full text
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Lymphocryptovirus-dependent occurrence of lymphoma in SIV-infected rhesus macaques with particular consideration to two uncommon cases of non-Hodgkin's lymphoma
Published in Primate Biology (20-12-2016)“…Despite combination antiretroviral therapy, high-grade malignant non-Hodgkin's lymphoma (NHL) is still one of the most frequently acquired immunodeficiency…”
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