Search Results - "Neuman, Toomas"

Non-Invasive Assessment of Skin Surface Proteins of Psoriasis Vulgaris Patients in Response to Biological Therapy by Orro, Kadri, Salk, Kristiina, Merkulova, Anna, Abram, Kristi, Karelson, Maire, Traks, Tanel, Neuman, Toomas, Spee, Pieter, Kingo, Külli

“…Measurements of skin surface biomarkers have enormous value for the detailed assessment of skin conditions, both for clinical application and in skin care. The…”
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Targeted alternative splicing of TAF4: a new strategy for cell reprogramming by Kazantseva, Jekaterina, Sadam, Helle, Neuman, Toomas, Palm, Kaia

“…Reprogramming of somatic cells has become a versatile tool for biomedical research and for regenerative medicine. In the current study, we show that…”
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Neuralized family member NEURL1 is a ubiquitin ligase for the cGMP-specific phosphodiesterase 9A by Taal, Kati, Tuvikene, Jürgen, Rullinkov, Grete, Piirsoo, Marko, Sepp, Mari, Neuman, Toomas, Tamme, Richard, Timmusk, Tõnis

“…Neuralized functions as a positive regulator of the Notch pathway by promoting ubiquitination of Notch ligands via its E3 ligase activity, resulting in their…”
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LXXLL peptide converts transportan 10 to a potent inducer of apoptosis in breast cancer cells by Tints, Kairit, Prink, Madis, Neuman, Toomas, Palm, Kaia

“…Degenerate expression of transcription coregulator proteins is observed in most human cancers. Therefore, in targeted anti-cancer therapy development,…”
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RNA-seq analysis reveals different dynamics of differentiation of human dermis- and adipose-derived stromal stem cells by Jääger, Kersti, Islam, Saiful, Zajac, Pawel, Linnarsson, Sten, Neuman, Toomas

“…Tissue regeneration and recovery in the adult body depends on self-renewal and differentiation of stem and progenitor cells. Mesenchymal stem cells (MSCs) that…”
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Hybrid graphene–ceramic nanofibre network for spontaneous neural differentiation of stem cells by Kazantseva, Jekaterina, Hussainova, Irina, Ivanov, Roman, Neuman, Toomas, Gasik, Michael

“…A challenge in regenerative medicine is governed by the need to have control over the fate of stem cells that is regulated by the physical and chemical…”
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Alternative splicing targeting the hTAF4-TAFH domain of TAF4 represses proliferation and accelerates chondrogenic differentiation of human mesenchymal stem cells by Kazantseva, Jekaterina, Kivil, Anri, Tints, Kairit, Kazantseva, Anna, Neuman, Toomas, Palm, Kaia

“…Transcription factor IID (TFIID) activity can be regulated by cellular signals to specifically alter transcription of particular subsets of genes. Alternative…”
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Assessment of soluble skin surface protein levels for monitoring psoriasis vulgaris in adult psoriasis patients using non-invasive transdermal analysis patch: A pilot study by Orro, Kadri, Salk, Kristiina, Abram, Kristi, Arshavskaja, Jelena, Meikas, Anne, Karelson, Maire, Neuman, Toomas, Kingo, Külli, Spee, Pieter

“…To improve the care of patients with chronic inflammatory skin conditions, such as psoriasis, there is a need for diagnostic methods that can facilitate…”
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Prostaglandin D2 Receptor DP1 Antibodies Predict Vaccine-induced and Spontaneous Narcolepsy Type 1: Large-scale Study of Antibody Profiling by Sadam, Helle, Pihlak, Arno, Kivil, Anri, Pihelgas, Susan, Jaago, Mariliis, Adler, Priit, Vilo, Jaak, Vapalahti, Olli, Neuman, Toomas, Lindholm, Dan, Partinen, Markku, Vaheri, Antti, Palm, Kaia

“…Neuropathological findings support an autoimmune etiology as an underlying factor for loss of orexin-producing neurons in spontaneous narcolepsy type 1…”
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Blocking HES1 Expression Initiates GABAergic Differentiation and Induces the Expression of p21CIP1/WAF1 in Human Neural Stem Cells by Kabos, Peter, Kabosova, Andrea, Neuman, Toomas

“…Mammalian neural stem cells can develop into a variety of neuronal and glial cell types. This involves a highly coordinated process of differentiation in which…”
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Graphene-augmented nanofiber scaffolds demonstrate new features in cells behaviour by Kazantseva, Jekaterina, Ivanov, Roman, Gasik, Michael, Neuman, Toomas, Hussainova, Irina

“…Three-dimensional (3D) customized scaffolds capable to mimic a native extracellular matrix open new frontiers in cells manipulation and advanced therapy. The…”
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The GAP-43 Gene Is a Direct Downstream Target of the Basic Helix-Loop-Helix Transcription Factors by Chiaramello, A, Neuman, T, Peavy, D R, Zuber, M X

“…The GAP-43 promoter region contains seven E-boxes (E1 to E7) that are organized in two clusters, a distal cluster (E3 to E7) and a proximal cluster (E1 and…”
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Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis by Laudański, Piotr, Rogalska, Gabriela, Warzecha, Damian, Lipa, Michał, Mańka, Grzegorz, Kiecka, Mariusz, Spaczyński, Robert, Piekarski, Piotr, Banaszewska, Beata, Jakimiuk, Artur, Issat, Tadeusz, Rokita, Wojciech, Młodawski, Jakub, Szubert, Maria, Sieroszewski, Piotr, Raba, Grzegorz, Szczupak, Kamil, Kluz, Tomasz, Kluza, Marek, Neuman, Toomas, Adler, Priit, Peterson, Hedi, Salumets, Andres, Wielgos, Miroslaw

“…Abstract STUDY QUESTION Are there specific autoantibody profiles in patients with endometriosis that are different from those in controls? SUMMARY ANSWER This…”
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Abstract 4039: Mimotope variance analysis: A novel immunoprofiling method to monitor progression of cervical cancer by Enerly, Espen, Nygård, Mari, Orumaa, Madleen, Pihlak, Arno, Pihelgas, Susan, Langseth, Hilde, Neuman, Toomas, Palm, Kaia

“…The purpose of the study was to identify and describe cervical cancer specific changes in humoral immune response by using a novel technology platform Mimotope…”
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GLI2 cell-specific activity is controlled at the level of transcription and RNA processing: Consequences to cancer metastasis by Sadam, Helle, Liivas, Urmas, Kazantseva, Anna, Pruunsild, Priit, Kazantseva, Jekaterina, Timmusk, Tõnis, Neuman, Toomas, Palm, Kaia

“…High activity of GLI family zinc finger protein 2 (GLI2) promotes tumor progression. Removal of the repressor domain at the N terminus (GLI2∆N) by recombinant…”
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TAF4 Controls Differentiation of Human Neural Progenitor Cells Through hTAF4-TAFH Activity by Kazantseva, Jekaterina, Tints, Kairit, Neuman, Toomas, Palm, Kaia

“…Expression of general transcription factor and co-activator TAF4 varies during development and in the processes of cell differentiation with suggested…”
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Human dermal fibroblasts exhibit delayed adipogenic differentiation compared with mesenchymal stem cells by Jääger, Kersti, Neuman, Toomas

“…Human dermal fibroblasts (FBs) express mesenchymal stem cell (MSC)-specific cell surface markers and differentiate into several cell types under appropriate…”
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Protein kinase inhibitor SU6668 attenuates positive regulation of Gli proteins in cancer and multipotent progenitor cells by Piirsoo, Alla, Kasak, Lagle, Kauts, Mari-Liis, Loog, Mart, Tints, Kairit, Uusen, Piia, Neuman, Toomas, Piirsoo, Marko

“…Observations that Glioma-associated transcription factors Gli1 and Gli2 (Gli1/2), executers of the Sonic Hedgehog (Shh) signaling pathway and targets of the…”
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Orphan receptor COUP-TF I antagonizes retinoic acid-induced neuronal differentiation by Neuman, K, Soosaar, A, Nornes, H O, Neuman, T

“…Chicken ovalbumin upstream promoter-transcription factors (COUP-TF) are expressed in the developing nervous system and interact with nuclear hormone receptors…”
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Variable expression of lineage regulators in differentiated stromal cells indicates distinct mechanisms of differentiation towards common cell fate by Jääger, Kersti, Fatkina, Angelika, Velts, Anna, Orav, Ester, Neuman, Toomas

“…Mesenchymal stem cells (MSCs) possess a multi-lineage differentiation capacity that makes them important players in the field of regenerative medicine. MSC…”
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