Neurobehavioral and Neurophysiological Outcome of Chronic Low-Level Tetrachloroethene Exposure Measured in Neighborhoods of Dry Cleaning Shops

Neurobehavioral and Neurophysiological Outcome of Chronic Low-Level Tetrachloroethene Exposure Measured in Neighborhoods of Dry Cleaning Shops

The effects of chronic low-level tetrachloroethene (TCE) exposure on functions of the central nervous system (CNS) were measured in subjects living in the neighborhood of dry cleaning shops with a mean residential time of 10.6 years. Neurobehavioral tests were performed using a German version of the...

Full description

Saved in:
Bibliographic Details
Published in:Environmental research Vol. 69; no. 2; pp. 83 - 89
Main Authors: Altmann, L., Neuhann, H.F., Kramer, U., Witten, J., Jermann, E.
Format: Journal Article
Language:English
Published: Amsterdam Elsevier Inc 01-05-1995
Elsevier
Subjects:
Adult
Air Pollutants - adverse effects
Air Pollutants - analysis
Air Pollution, Indoor - adverse effects
Air Pollution, Indoor - analysis
Biological and medical sciences
Central Nervous System - drug effects
Chemical and industrial products toxicology. Toxic occupational diseases
Cognition - drug effects
Cohort Studies
Environmental Exposure
Evoked Potentials, Visual - drug effects
Female
Germany
Humans
Male
Medical sciences
Middle Aged
Psychomotor Performance - drug effects
Regression Analysis
Risk Factors
Solvents
Solvents - adverse effects
Solvents - analysis
Surveys and Questionnaires
Tetrachloroethylene - adverse effects
Tetrachloroethylene - analysis
Tetrachloroethylene - blood
Toxicology
Germany
Human
Pollutant
Organic solvent
Nervous system diseases
Chronic
Proximity
Toxicity
Low dose
Central nervous system
Environment
Exposure
Public health
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The effects of chronic low-level tetrachloroethene (TCE) exposure on functions of the central nervous system (CNS) were measured in subjects living in the neighborhood of dry cleaning shops with a mean residential time of 10.6 years. Neurobehavioral tests were performed using a German version of the NES battery. Additionally, pattern reversal visual-evoked potentials (VEPs) were recorded. The mean blood TCE concentration in the subjects was 17.8 μg/liter and the median indoor TCE air concentration measured in the residences was 1.36 mg/m3. The outcome of the NES subtests for vigilance, simple reaction time, as well as visual memory differed statistically significantly between the exposed subjects and the controls, whereas for VEP latencies the differences were statistically not significant. It is concluded that despite the low exposure levels, CNS functions might be affected by TCE in subjects living close to a dry cleaning facility if the exposure lasts for several years.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0013-9351
1096-0953
DOI:10.1006/enrs.1995.1028