Search Results - "Neubauer, Markus"

Functional repertoire of EV-associated miRNA profiles after lipoprotein depletion via ultracentrifugation and size exclusion chromatography from autologous blood products by Otahal, Alexander, Kuten-Pella, Olga, Kramer, Karina, Neubauer, Markus, Lacza, Zsombor, Nehrer, Stefan, De Luna, Andrea

“…Cartilage breakdown, inflammation and pain are hallmark symptoms of osteoarthritis, and autologous blood products such as citrate-anticoagulated platelet-rich…”
Get full text

Simlukafusp alfa (FAP-IL2v) immunocytokine is a versatile combination partner for cancer immunotherapy by Waldhauer, Inja, Gonzalez-Nicolini, Valeria, Freimoser-Grundschober, Anne, Nayak, Tapan K, Fahrni, Linda, Hosse, Ralf J, Gerrits, Danny, Geven, Edwin J W, Sam, Johannes, Lang, Sabine, Bommer, Esther, Steinhart, Virginie, Husar, Elisabeth, Colombetti, Sara, Van Puijenbroek, Erwin, Neubauer, Markus, Cline, J Mark, Garg, Pradeep K, Dugan, Gregory, Cavallo, Federica, Acuna, Gonzalo, Charo, Jehad, Teichgräber, Volker, Evers, Stefan, Boerman, Otto C, Bacac, Marina, Moessner, Ekkehard, Umaña, Pablo, Klein, Christian

“…Simlukafusp alfa (FAP-IL2v, RO6874281/RG7461) is an immunocytokine comprising an antibody against fibroblast activation protein α (FAP) and an IL-2 variant…”
Get full text

Culture of Hoffa fat pad mesenchymal stem/stromal cells on microcarrier suspension in vertical wheel bioreactor for extracellular vesicle production by Otahal, Alexander, Kramer, Karina, Neubauer, Markus, Gulová, Slavomira, Lacza, Zsombor, Nehrer, Stefan, Luna, Andrea De

“…Mesenchymal stromal cells (MSCs) are increasingly employed in regenerative medicine approaches for their immunomodulatory and anti-inflammatory properties,…”
Get full text

Regenerative Potential of Blood-Derived Products in 3D Osteoarthritic Chondrocyte Culture System by Kuten-Pella, Olga, De Luna, Andrea, Kramer, Karina, Neubauer, Markus, Nehrer, Stefan, Lacza, Zsombor

“…Intra-articular injection of different types of blood-derived products is gaining popularity and clinical importance in the treatment of degenerative cartilage…”
Get full text

Effects of Extracellular Vesicles from Blood-Derived Products on Osteoarthritic Chondrocytes within an Inflammation Model by Otahal, Alexander, Kramer, Karina, Kuten-Pella, Olga, Moser, Lukas B., Neubauer, Markus, Lacza, Zsombor, Nehrer, Stefan, De Luna, Andrea

“…Osteoarthritis (OA) is hallmarked by a progressive degradation of articular cartilage. One major driver of OA is inflammation, in which cytokines such as IL-6,…”
Get full text

Isolation and Cultivation of Adipose-Derived Mesenchymal Stem Cells Originating from the Infrapatellar Fat Pad Differentiated with Blood Products: Method and Protocol by Neubauer, Markus, Kramer, Karina, Neugebauer, Johannes, Moser, Lukas, Moser, Anna, Dammerer, Dietmar, Nehrer, Stefan

“…Adipose-derived mesenchymal stem cells (ASCs) are a promising source for clinical application in regenerative orthopedics. ASCs derived from the infra-patellar…”
Get full text

The Effect of Blood-Derived Products on the Chondrogenic and Osteogenic Differentiation Potential of Adipose-Derived Mesenchymal Stem Cells Originated from Three Different Locations by Nehrer, Stefan, Muellner, Thomas, De Luna, Andrea, Kramer, Karina, Stotter, Christoph, Kuten, Olga, Neubauer, Markus, Lacza, Zsombor

“…Background. Adipose-derived mesenchymal stem cells (AD-MSCs) from fat tissue considered “surgical waste” during joint surgery may provide a potent source for…”
Get full text

Medial Meniscal Allograft Transplantation: The Bone Plug Technique by Bartsch, Anna, Anderson, Forrest L., Neubauer, Markus, Vel, Monica S., Sherman, Seth L.

“…Background: The medial and lateral menisci act as shock absorbers for the knee joint by converting and redistributing axial load into circumferential hoop…”
Get full text

Orthopaedic surgeons display a positive outlook towards artificial intelligence: A survey among members of the AGA Society for Arthroscopy and Joint Surgery by Rupp, Marco‐Christopher, Moser, Lukas B., Hess, Silvan, Angele, Peter, Aurich, Matthias, Dyrna, Felix, Nehrer, Stefan, Neubauer, Markus, Pawelczyk, Johannes, Izadpanah, Kaywan, Zellner, Johannes, Niemeyer, Philipp

“…Purpose The purpose of this study was to evaluate the perspective of orthopaedic surgeons on the impact of artificial intelligence (AI) and to evaluate the…”
Get full text

Generation of mature fat pads in vitro and in vivo utilizing 3-D long-term culture of 3T3-L1 preadipocytes by Fischbach, Claudia, Spruß, Thilo, Weiser, Barbara, Neubauer, Markus, Becker, Christian, Hacker, Michael, Göpferich, Achim, Blunk, Torsten

“…Tissue-inherent factors such as cell–cell and cell–extracellular matrix interactions are regarded to exert a potentially large impact on adipogenesis as well…”
Get full text

Novel Tumor-Targeted, Engineered IL-2 Variant (IL2v)-Based Immunocytokines For Immunotherapy Of Cancer by Klein, Christian, Waldhauer, Inja, Nicolini, Valeria, Dunn, Claire, Freimoser-Grundschober, Anne, Danny, Gerrits, Boerman, Otto, Nayak, Tapan, Herter, Sylvia, Van Puijenbroek, Erwin, Ast, Oliver, Hofer, Thomas, Hosse, Ralf, Lang, Sabine, Neumann, Sebastian, Kettenberger, Hubert, Neubauer, Markus, Gorr, Ingo, Tuerck, Dietrich, Evers, Stefan, Gerdes, Christian, Levitsky, Victor, Bacac, Marina, Moessner, Ekkehard, Umana, Pablo

“…IL-2 therapy can lead to durable responses in cancer patients, but is associated with significant toxicity. None of the known IL-2-based immunocytokines has…”
Get full text

Polybrene enhances uptake of extracellular vesicles into osteoarthritic chondrocytes by Luna, Andrea De, Otahal, Alexander, Kramer, Karina, Neubauer, Markus, Lacza, Zsombor, Nehrer, Stefan

Get full text

435 - Polybrene enhances uptake of extracellular vesicles into osteoarthritic chondrocytes by Luna, Andrea De, Otahal, Alexander, Kramer, Karina, Neubauer, Markus, Lacza, Zsombor, Nehrer, Stefan

Get full text

417 - Larger-scale enrichment of extracellular vesicles of Hoffa-derived adipose MSCs from dynamic microcarrier suspension culture in vertical wheel bioreactor by Otahal, Alexander, Kramer, Karina, Neubauer, Markus, Lacza, Zsombor, Nehrer, Stefan, De Luna, Andrea

Get full text

Larger-scale enrichment of extracellular vesicles of Hoffa-derived adipose MSCs from dynamic microcarrier suspension culture in vertical wheel bioreactor by Otahal, Alexander, Kramer, Karina, Neubauer, Markus, Lacza, Zsombor, Nehrer, Stefan, De Luna, Andrea

Get full text

Mesenchymal stromal cell characteristics vary depending on their origin by Wegmeyer, Heike, Bröske, Ann-Marie, Leddin, Mathias, Kuentzer, Karin, Nisslbeck, Anna Katharina, Hupfeld, Julia, Wiechmann, Kornelius, Kuhlen, Jennifer, von Schwerin, Christoffer, Stein, Carsten, Knothe, Saskia, Funk, Jürgen, Huss, Ralf, Neubauer, Markus

“…Mesenchymal stromal cells (MSCs) are rare progenitor cells that can be isolated from various tissues. They exhibit multilineage differentiation potential,…”
Get more information

Adipose derived stem cells to target osteoarthritis: Basic science and clinical applications by Neubauer, Markus, Seist, Theodor, Dammerer, Dietmar, Nehrer, Stefan

“…Osteoarthritis (OA) is a common and debilitating disease. It is accompanied by pain and a progressive loss of mobility. Mesenchymal stem cells (MSCs) were…”
Get full text

Brachytherapy in the Treatment of Soft-Tissue Sarcomas of the Extremities-A Current Concept and Systematic Review of the Literature by Neugebauer, Johannes, Blum, Philipp, Keiler, Alexander, Süß, Markus, Neubauer, Markus, Moser, Lukas, Dammerer, Dietmar

“…Evidence on the use of brachytherapy in soft-tissue sarcoma (STS) is sparse. Therapy regimens are determined more by local interdisciplinary tumor conferences…”
Get full text

Infra-patellar fat pad-derived mesenchymal stem cells maintain their chondrogenic differentiation potential after arthroscopic harvest with blood-product supplementation by Neubauer, Markus, Otahal, Alexander, Kuten, Olga, Sherman, Seth Lawrence, Moser, Lukas, Kramer, Karina, DeLuna, Andrea, Neugebauer, Johannes, Dammerer, Dietmar, Muellner, Thomas, Nehrer, Stefan

“…Purpose Mesenchymal stem cells/medicinal signaling cells (MSCs) possess therapeutic potential and are used in regenerative orthopaedics. The infra-patellar fat…”
Get full text

Modulation of mesenchymal stromal cell characteristics by microcarrier culture in bioreactors by Hupfeld, Julia, Gorr, Ingo H., Schwald, Christian, Beaucamp, Nicola, Wiechmann, Kornelius, Kuentzer, Karin, Huss, Ralf, Rieger, Bernhard, Neubauer, Markus, Wegmeyer, Heike

“…ABSTRACT Mesenchymal stromal cells (MSCs) are promising candidates for cell therapy. Their therapeutic use requires extensive expansion to obtain a…”
Get full text