Search Results - "Neubauer, A."

Skyrmion Lattice in a Chiral Magnet by Mühlbauer, S, Binz, B, Jonietz, F, Pfleiderer, C, Rosch, A, Neubauer, A, Georgii, R, Böni, P

“…Skyrmions represent topologically stable field configurations with particle-like properties. We used neutron scattering to observe the spontaneous formation of…”
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Roles, regulation and inhibitors of sphingosine kinase 2 by Neubauer, Heidi A, Pitson, Stuart M

“…The bioactive sphingolipids ceramide, sphingosine and sphingosine‐1‐phosphate (S1P) are important signalling molecules that regulate a diverse array of…”
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Implications of STAT3 and STAT5 signaling on gene regulation and chromatin remodeling in hematopoietic cancer by Wingelhofer, Bettina, Neubauer, Heidi A., Valent, Peter, Han, Xiaonan, Constantinescu, Stefan N., Gunning, Patrick T., Müller, Mathias, Moriggl, Richard

“…STAT3 and STAT5 proteins are oncogenic downstream mediators of the JAK–STAT pathway. Deregulated STAT3 and STAT5 signaling promotes cancer cell proliferation…”
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Spin Transfer Torques in MnSi at Ultralow Current Densities by Jonietz, F, Mühlbauer, S, Pfleiderer, C, Neubauer, A, Münzer, W, Bauer, A, Adams, T, Georgii, R, Böni, P, Duine, R.A, Everschor, K, Garst, M, Rosch, A

“…Spin manipulation using electric currents is one of the most promising directions in the field of spintronics. We used neutron scattering to observe the…”
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Onset of Late Cretaceous diversification in Europe’s freshwater gastropod fauna links to global climatic and biotic events by Neubauer, Thomas A., Harzhauser, Mathias

“…The Mesozoic rise of the European freshwater gastropod fauna is still poorly understood. Compared to the well documented Cenozoic history, little is known…”
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Topological Hall effect in the A phase of MnSi by Neubauer, A, Pfleiderer, C, Binz, B, Rosch, A, Ritz, R, Niklowitz, P G, Böni, P

“…Recent small angle neutron scattering suggests that the spin structure in the A phase of MnSi is a so-called triple-Q state, i.e., a superposition of three…”
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Long-term cognitive outcomes of extremely low-birth-weight infants: the influence of the maternal educational background by Voss, W, Jungmann, T, Wachtendorf, M, Neubauer, AP

“…Aim:  The purpose of the present contribution is to analyse the relationships between perinatal risk factors, social parameters and neurodevelopmental outcomes…”
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Safety and efficacy of imatinib in CML over a period of 10 years: data from the randomized CML-study IV by Kalmanti, L, Saussele, S, Lauseker, M, Müller, M C, Dietz, C T, Heinrich, L, Hanfstein, B, Proetel, U, Fabarius, A, Krause, S W, Rinaldetti, S, Dengler, J, Falge, C, Oppliger-Leibundgut, E, Burchert, A, Neubauer, A, Kanz, L, Stegelmann, F, Pfreundschuh, M, Spiekermann, K, Scheid, C, Pfirrmann, M, Hochhaus, A, Hasford, J, Hehlmann, R

“…Tyrosine kinase inhibitors (TKI) have changed the natural course of chronic myeloid leukemia (CML). With the advent of second-generation TKI safety and…”
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The Central Paratethys Sea—rise and demise of a Miocene European marine biodiversity hotspot by Harzhauser, Mathias, Landau, Bernard, Mandic, Oleg, Neubauer, Thomas A.

“…The Miocene Climate Optimum (MCO, ~ 17–14 Ma) was a time of extraordinary marine biodiversity in the Circum-Mediterranean Region. This boom is best recorded in…”
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The stromal microenvironment provides an escape route from FLT3 inhibitors through the GAS6-AXL-STAT5 axis by Orlova, Anna, Neubauer, Heidi A, Moriggl, Richard

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Assessment of imatinib as first-line treatment of chronic myeloid leukemia: 10-year survival results of the randomized CML study IV and impact of non-CML determinants by Hehlmann, R, Lauseker, M, Saußele, S, Pfirrmann, M, Krause, S, Kolb, H J, Neubauer, A, Hossfeld, D K, Nerl, C, Gratwohl, A, Baerlocher, G M, Heim, D, Brümmendorf, T H, Fabarius, A, Haferlach, C, Schlegelberger, B, Müller, M C, Jeromin, S, Proetel, U, Kohlbrenner, K, Voskanyan, A, Rinaldetti, S, Seifarth, W, Spieß, B, Balleisen, L, Goebeler, M C, Hänel, M, Ho, A, Dengler, J, Falge, C, Kanz, L, Kremers, S, Burchert, A, Kneba, M, Stegelmann, F, Köhne, C A, Lindemann, H W, Waller, C F, Pfreundschuh, M, Spiekermann, K, Berdel, W E, Müller, L, Edinger, M, Mayer, J, Beelen, D W, Bentz, M, Link, H, Hertenstein, B, Fuchs, R, Wernli, M, Schlegel, F, Schlag, R, de Wit, M, Trümper, L, Hebart, H, Hahn, M, Thomalla, J, Scheid, C, Schafhausen, P, Verbeek, W, Eckart, M J, Gassmann, W, Pezzutto, A, Schenk, M, Brossart, P, Geer, T, Bildat, S, Schäfer, E, Hochhaus, A, Hasford, J

“…Chronic myeloid leukemia (CML)-study IV was designed to explore whether treatment with imatinib (IM) at 400 mg/day ( n =400) could be optimized by doubling the…”
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RBFOX1 and RBFOX3 mutations in rolandic epilepsy by Lal, Dennis, Reinthaler, Eva M, Altmüller, Janine, Toliat, Mohammad R, Thiele, Holger, Nürnberg, Peter, Lerche, Holger, Hahn, Andreas, Møller, Rikke S, Muhle, Hiltrud, Sander, Thomas, Zimprich, Fritz, Neubauer, Bernd A

“…Partial deletions of the gene encoding the neuronal splicing regulator RBFOX1 have been reported in a range of neurodevelopmental diseases, including…”
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Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multicenter survey by Zeiser, R, Burchert, A, Lengerke, C, Verbeek, M, Maas-Bauer, K, Metzelder, S K, Spoerl, S, Ditschkowski, M, Ecsedi, M, Sockel, K, Ayuk, F, Ajib, S, de Fontbrune, F S, Na, I-K, Penter, L, Holtick, U, Wolf, D, Schuler, E, Meyer, E, Apostolova, P, Bertz, H, Marks, R, Lübbert, M, Wäsch, R, Scheid, C, Stölzel, F, Ordemann, R, Bug, G, Kobbe, G, Negrin, R, Brune, M, Spyridonidis, A, Schmitt-Gräff, A, van der Velden, W, Huls, G, Mielke, S, Grigoleit, G U, Kuball, J, Flynn, R, Ihorst, G, Du, J, Blazar, B R, Arnold, R, Kröger, N, Passweg, J, Halter, J, Socié, G, Beelen, D, Peschel, C, Neubauer, A, Finke, J, Duyster, J, von Bubnoff, N

“…Despite major improvements in allogeneic hematopoietic cell transplantation over the past decades, corticosteroid-refractory (SR) acute (a) and chronic (c)…”
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Combined fluorescence and phosphorescence lifetime imaging by Shcheslavskiy, V. I., Neubauer, A., Bukowiecki, R., Dinter, F., Becker, W.

“…We present a lifetime imaging technique that simultaneously records the fluorescence and phosphorescence lifetime images in confocal laser scanning systems. It…”
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Expression of the CTLA-4 ligand CD86 on plasmacytoid dendritic cells (pDC) predicts risk of disease recurrence after treatment discontinuation in CML by Schütz, C, Inselmann, S, Sausslele, S, Dietz, C T, Müller, M C, Eigendorff, E, Brendel, C A, Metzelder, S K, Brümmendorf, T H, Waller, C, Dengler, J, Goebeler, M E, Herbst, R, Freunek, G, Hanzel, S, Illmer, T, Wang, Y, Lange, T, Finkernagel, F, Hehlmann, R, Huber, M, Neubauer, A, Hochhaus, A, Guilhot, J, Xavier Mahon, F, Pfirrmann, M, Burchert, A

“…It is unknown, why only a minority of chronic myeloid leukemia (CML) patients sustains treatment free remission (TFR) after discontinuation of tyrosine kinase…”
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Neutron depolarization imaging of the hydrostatic pressure dependence of inhomogeneous ferromagnets by Schulz, M., Neubauer, A., Böni, P., Pfleiderer, C.

“…The investigation of fragile and potentially inhomogeneous forms of ferromagnetic order under extreme conditions, such as low temperatures and high pressures,…”
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Tectonics, climate, and the rise and demise of continental aquatic species richness hotspots by Neubauer, Thomas A., Harzhauser, Mathias, Georgopoulou, Elisavet, Kroh, Andreas, Mandic, Oleg

“…Continental aquatic species richness hotspots are unevenly distributed across the planet. In present-day Europe, only two centers of biodiversity exist (Lake…”
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Direct Targeting Options for STAT3 and STAT5 in Cancer by Orlova, Anna, Wagner, Christina, de Araujo, Elvin D, Bajusz, Dávid, Neubauer, Heidi A, Herling, Marco, Gunning, Patrick T, Keserű, György M, Moriggl, Richard

“…Signal transducer and activator of transcription (STAT)3 and STAT5 are important transcription factors that are able to mediate or even drive cancer…”
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Opioids drive breast cancer metastasis through the δ-opioid receptor and oncogenic STAT3 by Tripolt, Sabrina, Neubauer, Heidi A., Knab, Vanessa M., Elmer, Dominik P., Aberger, Fritz, Moriggl, Richard, Fux, Daniela A.

“…The opioid crisis of pain medication bears risks from addiction to cancer progression, but little experimental evidence exists. Expression of δ-opioid…”
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Randomized Phase II Trial of Erlotinib With and Without Entinostat in Patients With Advanced Non–Small-Cell Lung Cancer Who Progressed on Prior Chemotherapy by WITTA, Samir E, JOTTE, Robert M, KONDURI, Katrik, NEUBAUER, Marcus A, SPIRA, Alexander I, RUXER, Robert L, VARELLA-GARCIA, Marileila, BUNN, Paul A, HIRSCH, Fred R

“…Histone deacetylase inhibitors (HDACis) have been shown to overcome resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs)…”
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