Search Results - "Netzer, Nir"
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Mitigation of Lethal Radiation Syndrome in Mice by Intramuscular Injection of 3D Cultured Adherent Human Placental Stromal Cells
Published in PloS one (18-06-2013)“…Exposure to high lethal dose of ionizing radiation results in acute radiation syndrome with deleterious systemic effects to different organs. A primary target…”
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Human PLacental eXpanded (PLX) mesenchymal-like adherent stromal cells confer neuroprotection to nerve growth factor (NGF)-differentiated PC12 cells exposed to ischemia by secretion of IL-6 and VEGF
Published in Biochimica et biophysica acta (01-02-2015)“…Mesenchymal stem cells are potent candidates in stroke therapy due to their ability to secrete protective anti-inflammatory cytokines and growth factors. We…”
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Innate immune and chemically triggered oxidative stress modifies translational fidelity
Published in Nature (London) (26-11-2009)“…Translational fidelity, essential for protein and cell function, requires accurate transfer RNA (tRNA) aminoacylation. Purified aminoacyl-tRNA synthetases…”
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Direct visualization of the dynamics of antigen presentation in human cells infected with cytomegalovirus revealed by antibodies mimicking TCR specificity
Published in European journal of immunology (01-06-2010)“…There are no direct means to study class I MHC presentation in human normal or diseased cells. Using CMV‐infected human cells and applying novel mAb that mimic…”
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Plasmid DNA encoding IFN-gamma-inducible protein 10 redirects antigen-specific T cell polarization and suppresses experimental autoimmune encephalomyelitis
Published in The Journal of immunology (1950) (01-06-2002)“…IFN-gamma-inducible protein 10 (IP-10) is a CXC chemokine that stimulates the directional migration of activated T cells, particularly Th1 cells. We…”
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Long-Term Efficacy of GMP Grade Xeno-Free hESC-Derived RPE Cells Following Transplantation
Published in Translational vision science & technology (14-06-2017)“…Retinal pigment epithelium (RPE) dysfunction underlies the retinal degenerative process in age-related macular degeneration (AMD), and thus RPE cell…”
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Tr1 cell-dependent active tolerance blunts the pathogenic effects of determinant spreading
Published in The Journal of clinical investigation (01-09-2002)“…Experimental autoimmune encephalomyelitis (EAE) is a T cell-mediated autoimmune disease of the CNS. The current study shows that even in an acute episode of…”
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Cover Picture: Eur. J. Immunol. 6/10
Published in European journal of immunology (01-06-2010)“…The cover image of this issue consists of confocal images of cytomegalovirus‐infected human fibroblast cells stained for HLA‐A2/pp65 complexes, taken from…”
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Targeting the function of IFN-gamma-inducible protein 10 suppresses ongoing adjuvant arthritis
Published in The Journal of immunology (1950) (01-09-2002)“…IFN-gamma-inducible protein 10 (IP-10) is a CXC chemokine that is thought to manifest a proinflammatory role because it stimulates the directional migration of…”
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The Exception that Reinforces the Rule: Crosspriming by Cytosolic Peptides that Escape Degradation
Published in Immunity (Cambridge, Mass.) (01-06-2008)“…The nature of crosspriming immunogens for CD8 + T cell responses is highly controversial. By using a panel of T cell receptor-like antibodies specific for…”
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RNA Binding Targets Aminoacyl-tRNA Synthetases to Translating Ribosomes
Published in The Journal of biological chemistry (10-06-2011)“…Here, we examine tRNA-aminoacyl synthetase (ARS) localization in protein synthesis. Proteomics reveals that ten of the twenty cytosolic ARSs associate with…”
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Tr1 cell–dependent active tolerance blunts the pathogenic effects of determinant spreading
Published in The Journal of clinical investigation (01-09-2002)“…Experimental autoimmune encephalomyelitis (EAE) is a T cell–mediated autoimmune disease of the CNS. The current study shows that even in an acute episode of…”
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Targeted Overexpression of IL-18 Binding Protein at the Central Nervous System Overrides Flexibility in Functional Polarization of Antigen-Specific Th2 Cells
Published in The Journal of immunology (1950) (01-04-2005)“…The current study shows that functional polarization of Ag-specific CD4(+) Th2 cells entering the CNS during the accelerating phase of experimental autoimmune…”
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The Exception that Reinforces the Rule: Cross-Priming by Cytosolic Peptides that Escape Degradation
Published in Immunity (Cambridge, Mass.) (01-06-2008)“…The nature of cross-priming immunogens for CD8+ T cell responses is highly controversial. Using a panel of T cell receptor-like antibodies specific for viral…”
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Targeting the Function of IFN-{gamma}-Inducible Protein 10 Suppresses Ongoing Adjuvant Arthritis
Published in The Journal of immunology (1950) (01-09-2002)“…IFN-[gamma]-inducible protein 10 (IP-10) is a CXC chemokine that is thought to manifest a proinflammatory role because it stimulates the directional migration…”
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