Search Results - "Neto, Fani"

µ-opioid receptor activation at the dorsal reticular nucleus shifts diffuse noxious inhibitory controls to hyperalgesia in chronic joint pain in male rats by Pereira-Silva, Raquel, Teixeira-Pinto, Armando, Neto, Fani L, Martins, Isabel

“…The dorsal reticular nucleus is a pain facilitatory area involved in the diffuse noxious inhibitory controls (DNIC), through opioidergic mechanisms that are…”
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Neurotrophins Role in Depression Neurobiology: A Review of Basic and Clinical Evidence by Neto, Fani L, Borges, Gisela, Torres-Sanchez, Sonia, Mico, Juan A, Berrocoso, Esther

“…Depression is a neuropsychiatric disorder affecting a huge percentage of the active population especially in developed countries. Research has devoted much of…”
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Satellite glial cells in sensory ganglia: its role in pain by Costa, Filipa Alexandra Leite, Neto, Fani Lourença Moreira

“…Satellite glial cells in sensory ganglia are a recent subject of research in the field of pain and a possible therapeutic target in the future. Therefore, the…”
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Attenuation of the Diffuse Noxious Inhibitory Controls in Chronic Joint Inflammatory Pain Is Accompanied by Anxiodepressive-Like Behaviors and Impairment of the Descending Noradrenergic Modulation by Pereira-Silva, Raquel, Costa-Pereira, José Tiago, Alonso, Raquel, Serrão, Paula, Martins, Isabel, Neto, Fani L

“…The noradrenergic system is paramount for controlling pain and emotions. We aimed at understanding the descending noradrenergic modulatory mechanisms in joint…”
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Satellite glial cells surrounding primary afferent neurons are activated and proliferate during monoarthritis in rats: is there a role for ATF3? by Nascimento, Diana Sofia Marques, Castro-Lopes, José Manuel, Moreira Neto, Fani Lourença

“…Joint inflammatory diseases are debilitating and very painful conditions that still lack effective treatments. Recently, glial cells were shown to be crucial…”
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Social stress exacerbates the aversion to painful experiences in rats exposed to chronic pain: The role of the locus coeruleus by Bravo, Lidia, Alba-Delgado, Cristina, Torres-Sanchez, Sonia, Mico, Juan Antonio, Neto, Fani L., Berrocoso, Esther

“…Isolation selectively exerts a negative influence on the affective pain experience by increased evoked activity of the locus coeruleus under neuropathic pain…”
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Amylin, a peptide expressed by nociceptors, modulates chronic neuropathic pain by Almeida, Lígia Sofia, Castro‐Lopes, José Manuel, Neto, Fani Lourença, Potes, Catarina Soares

“…Background Amylin is a calcitonin gene‐related peptide family member expressed by nociceptors. Amylin's expression is down‐regulated following nerve damage,…”
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Editorial: Women in science: neuropathic pain by Martins, Isabel, Golden, Judith P., Neto, Fani Lourença

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ERK1/2: Function, signaling and implication in pain and pain-related anxio-depressive disorders by Borges, Gisela, Berrocoso, Esther, Mico, Juan Antonio, Neto, Fani

“…Despite the increasing knowledge regarding pain modulation, the understanding of the mechanisms behind a complex and pathologic chronic pain condition is still…”
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Diffuse noxious inhibitory controls in chronic joint inflammatory Pain: Study of the descending serotonergic modulation mediated through 5HT3 receptors by Pereira-Silva, Raquel, Serrão, Paula, Lourença Neto, Fani, Martins, Isabel

“…The loss of diffuse noxious inhibitory controls (DNIC) is recognized as a predictor of chronic pain. Mechanistically, DNIC produces analgesia by a…”
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Reversal of Monoarthritis-induced Affective Disorders by Diclofenac in Rats by Borges, Gisela, Neto, Fani, Mico, Juan Antonio, Berrocoso, Esther

“…BACKGROUND:Nonsteroidal anti-inflammatory drugs are effective for arthritic pain, but it is unknown whether they also benefit anxiety and depression that…”
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TLR4 Antagonism Reduces Movement-Induced Nociception and ATF-3 Expression in Experimental Osteoarthritis by Ferreira-Gomes, Joana, Garcia, Miguel M, Nascimento, Diana, Almeida, Lígia, Quesada, Ernesto, Castro-Lopes, José Manuel, Pascual, David, Goicoechea, Carlos, Neto, Fani Lourença

“…Toll-like receptor 4 (TLR4) is a pattern recognition receptor involved in the detection of pathogen-associated molecular patterns (PAMPs), but also a…”
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Intra-articular injection of collagenase in the knee of rats as an alternative model to study nociception associated with osteoarthritis by Adães, Sara, Mendonça, Marcelo, Santos, Telmo N, Castro-Lopes, José M, Ferreira-Gomes, Joana, Neto, Fani L

“…Animal models currently used in osteoarthritis-associated pain research inadequately reproduce the initiating events and structural pathology of human…”
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Drug-Induced HSP90 Inhibition Alleviates Pain in Monoarthritic Rats and Alters the Expression of New Putative Pain Players at the DRG by Nascimento, Diana Sofia Marques, Potes, Catarina Soares, Soares, Miguel Luz, Ferreira, António Carlos, Malcangio, Marzia, Castro-Lopes, José Manuel, Neto, Fani Lourença Moreira

“…Purinergic receptors (P2XRs) have been widely associated with pain states mostly due to their involvement in neuron–glia communication. Interestingly, we have…”
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Corticotropin-Releasing Factor Mediates Pain-Induced Anxiety through the ERK1/2 Signaling Cascade in Locus Coeruleus Neurons by Borges, Gisela Patrícia, Micó, Juan Antonio, Neto, Fani Lourença, Berrocoso, Esther

“…Background: The corticotropin-releasing factor is a stress-related neuropeptide that modulates locus coeruleus activity. As locus coeruleus has been involved…”
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Glial activation in the collagenase model of nociception associated with osteoarthritis by Adães, Sara, Almeida, Lígia, Potes, Catarina S, Ferreira, Ana Rita, Castro-Lopes, José M, Ferreira-Gomes, Joana, Neto, Fani L

“…Background Experimental osteoarthritis entails neuropathic-like changes in dorsal root ganglia (DRG) neurons. Since glial activation has emerged as a key…”
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Spared nerve injury model to study orofacial pain by Pozza, Daniel, Castro-Lopes, José, Neto, Fani, Avelino, António

“…Background & objectives: There are many difficulties in generating and testing orofacial pain in animal models. Thus, only a few and limited models that mimic…”
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Modeling Chronic Pain Experiences from Online Reports Using the Reddit Reports of Chronic Pain Dataset by Nunes, Diogo A. P., Ferreira-Gomes, Joana, Neto, Fani, Martins de Matos, David

“…Reported experiences of chronic pain may convey qualities relevant to the exploration of this private and subjective experience. We propose this exploration by…”
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The function of alpha-2-adrenoceptors in the rat locus coeruleus is preserved in the chronic constriction injury model of neuropathic pain by Alba-Delgado, Cristina, Borges, Gisela, Sánchez-Blázquez, Pilar, Ortega, Jorge E., Horrillo, Igor, Mico, Juan A., Meana, J. Javier, Neto, Fani, Berrocoso, Esther

“…Rationale Peripheral neuropathic pain is a chronic condition that may produce plastic changes in several brain regions. The noradrenergic locus coeruleus (LC)…”
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Neuronal Injury Marker ATF-3 Is Induced in Primary Afferent Neurons of Monoarthritic Rats by Nascimento, Diana, Pozza, Daniel Humberto, Castro-Lopes, José Manuel, Neto, Fani Lourença

“…Activating transcription factor 3 (ATF-3) expression has been associated with several signaling pathways implicated in cellular stress response in many cell…”
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