Search Results - "Nessim, Christine K."

A sustainable HPLC method coupled with diode array detection for versatile quantification of telmisartan, chlorthalidone and amlodipine in a fixed-dose antihypertensive formulation and dissolution studies by Kamel, Mona A., Nessim, Christine K., Michael, Adel M., Abbas, Samah S., Marzouk, Hoda M.

“…Cardiovascular diseases, especially hypertension, stand as prominent contributors to global mortality. Hypertension, often referred to as a silent killer…”
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A high-throughput UPLC-MS-MS Bio-analytical method for the analysis of veterinary pharmaceutical residues in Chicken Tissues, Application of efficient-valid-green (EVG) Framework as a Competence Tool by Saleh, Sarah S., Samir, Ahmed, Lotfy, Hayam M., Nessim, Christine K.

“…•UPLC-MS-MS for determination of veterinary residues.•Residues sulfadimidine, sulfaquinoxaline, diaveridine, vitamin K3 in poultry tissues.•Decline curve study…”
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Utility of N-Bromosuccinimide-Water Combination as a Green Reagents for a Validated Indirect Spectrophotometric Determination of Some Antihypertensive Drugs: An Application to Their Monitoring in Marketed Tablets and Capsules by Helmy, Marwa I, Nessim, Christine K

“…Analytical tests were conducted to investigate the use of N-bromosuccinimide (NBS) as an important, safe analytical reagent for the spectrophotometric…”
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Innovative anti-proliferative effect of the antiviral favipiravir against MCF-7 breast cancer cells using green nanoemulsion and eco-friendly assessment tools by Abd-Elrasheed, Eman, Fahim, Sally A., Nessim, Christine K., El-Helaly, Sara Nageeb

“…Telomerase enzyme prevents telomere shortening during division, having human telomerase reverse transcriptase (hTERT) as its catalytic subunit. Favipiravir…”
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Development and Evaluation of Chemometric Models for the Estimation of Sumatriptan in the Presence of Naproxen and a Degradation Product Using UV Spectrophotometry by Michael, Adel M, Lotfy, Hayam M, Rezk, Mamdouh R, Nessim, Christine K

“…Chemometrics is a discipline that allows the spectral resolution of drugs in a pharmaceutical formulation along with degradation product and it is as an…”
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Enhancing the Sustainability of Eco-friendly Potentiometric Ion Selective Electrodes for Stability-Indicating Measurement of Ethamsylate: Application in Bulk and Pharmaceutical Formulations by Monir, Hany H, Mohamed, Heba A, Badawy, Amr M, Nebsen, Marianne, Nessim, Christine K

“…Through the use of sustainable and green chemistry concepts, scientists need to decrease waste, conserve energy, and develop safe substitutes for hazardous…”
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When is it safe to eat different broiler chicken tissues after administration of doxycycline and tylosin mixture? by Monir, Hany H., Fayez, Yasmin M., Nessim, Christine K., Michael, Adel M.

“…Residues of veterinary drugs in poultry meat have serious health effects on humans (e.g., antimicrobial resistance, carcinogenicity, and hypersensitivity),…”
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Nano-scale multi-spectroscopic analysis of the anti-fibromyalgia drug pregabalin based on dihydropyridine ring formation with sustainability and whiteness evaluation by El Hamd, Mohamed A., Obaydo, Reem H., Ibrahim Helmy, Marwa, Mahdi, Wael A., Alshehri, Sultan, El-Maghrabey, Mahmoud, Nessim, Christine K.

“…[Display omitted] •Multiple-spectroscopic assay of the non-chromophoric zwitterionic drug pregabalin.•Employing Hantzsch’s one-pot cyclization reaction in…”
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A Thorough HPLC Assay of Quaternary Veterinary Formulation coupled with Environmental Assessment Tool by Michael, Adel M, Fayez, Yasmin M, Monir, Hany H, Nessim, Christine K

“…Abstract A new and accurate reversed phase HPLC method with UV detection has been established for any veterinarian analyst for simultaneous determination of a…”
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Comprehensive comparative study of eco-friendly Univariate and multivariate methodological approaches on processing multi-component formulation quality by Fayez, Yasmin M., Michael, Adel M., Monir, Hany H., Lotfy, Hayam M., Nessim, Christine K.

“…This study presents comprehensive comparative study of different eco-friendly spectrophotometric approaches without any sample treatment on processing…”
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Simultaneous determination of mebeverine hydrochloride and chlordiazepoxide in their binary mixture using novel univariate spectrophotometric methods via different manipulation pathways by Lotfy, Hayam M., Fayez, Yasmin M., Michael, Adel M., Nessim, Christine K.

“…Smart, sensitive, simple and accurate spectrophotometric methods were developed and validated for the quantitative determination of a binary mixture of…”
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Impact Study of Mathematical Manipulation on the Resolution Efficiency of the Spectrophotometric Technique—An Application on Veterinary Binary Mixture with Overlapping Absorption Bands by Lotfy, Hayam M, Monir, Hany H, Michael, Adel M, Fayez, Yasmin M, Nessim, Christine K

“…Abstract Background The impact of mathematical manipulation on the efficiency of smart spectrophotometric approaches was considered for analyzing a veterinary…”
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Novel Stability-Indicating Chemometric-Assisted Spectrophotometric Methods for the Determination of Chlordiazepoxide and Clidinium Bromide in the Presence of Clidinium Bromide's Alkali-Induced Degradation Product by Nessim, Christine K, Michael, Adel M, Fayez, Yasmin M, Lotfy, Hayam M

“…Two simple and accurate chemometric-assisted spectrophotometric models were developed and validated for the simultaneous determination of chlordiazepoxide…”
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Validated Stability-Indicating Chromatographic Methods for the Determination of Chlordiazepoxide and Clidinium Bromide in the Presence of its Alkali-Induced Degradation Product: Kinetic Study by Fayez, Yasmin M., Nessim, Christine K., Michael, Adel M., Lotfy, Hayam M.

“…Accurate, simple and selective stability-indicating reversed phase HPLC and TLC-densitometric methods with UV detection have been developed and validated for…”
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Greenness profile and whiteness assessment of the stability-indicating HPLC method for the assay of levetiracetam by Michael, Adel M., Lotfy, Hayam M., Nessim, Christine K.

“…[Display omitted] •The proposed method is green, selective and stability-indicating for determination of levetiracetam in Tiratam® dosage…”
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Spider chart and whiteness assessment of synergistic spectrophotometric strategy for quantification of triple combination recommended in seasonal influenza – Detection of spurious drug by Lotfy, Hayam M., Obaydo, Reem H., Nessim, Christine K.

“…Trimed Flu® Tablets are commonly specified to treat the cold, cough, and fever in clinical management protocol for seasonal influenza. These tablets comprise…”
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Corrigendum to “A green LC-MS/MS for energetically assessing an imperative muscle relaxant combination: A clinical pharmacokinetic study in human plasma” [Microchem. J. 202 (2024) 110848] by Helmy, Marwa I., Nessim, Christine K., El Hamd, Mohamed A.

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A green LC-MS/MS for energetically assessing an imperative muscle relaxant combination: A clinical pharmacokinetic study in human plasma by Helmy, Marwa I., Nessim, Christine K., Hamd, Mohamed A. El

“…[Display omitted] •An initial investigation used LC-MS/MS to identify the combination of SMRs: tolperisone HCl, paracetamol, and aceclofenac.•The…”
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Integrative AQbD, up-to-date greenness, and whiteness tools for evaluation of a sustainable RP-HPLC method used for simultaneous separation of triple antihypertensive combination therapy as a model by Kannaiah, Kanaka Parvathi, Chanduluru, Hemanth Kumar, Lotfy, Hayam M., Obaydo, Reem H., El Hamd, Mohamed A., Alshehri, Sultan, A. Mahdi, Wael, Nessim, Christine K.

“…The present study was designed to develop and validate a simple and fast RP-HPLC method for simultaneously evaluating hydrochlorothiazide (HCTZ), amlodipine…”
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