Search Results - "Nesi, Ilaria"
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Natural α-Glucosidase and Protein Tyrosine Phosphatase 1B Inhibitors: A Source of Scaffold Molecules for Synthesis of New Multitarget Antidiabetic Drugs
Published in Molecules (Basel, Switzerland) (09-08-2021)“…Diabetes mellitus (DM) represents a group of metabolic disorders that leads to acute and long-term serious complications and is considered a worldwide sanitary…”
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Activated fibroblasts enhance cancer cell migration by microvesicles-mediated transfer of Galectin-1
Published in Journal of cell communication and signaling (01-09-2021)“…Cancer-associated fibroblasts (CAFs) are one of the main components of the stromal compartment in the tumor microenvironment (TME) and the crosstalk between…”
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In Search for Multi-Target Ligands as Potential Agents for Diabetes Mellitus and Its Complications-A Structure-Activity Relationship Study on Inhibitors of Aldose Reductase and Protein Tyrosine Phosphatase 1B
Published in Molecules (Basel, Switzerland) (10-01-2021)“…Diabetes mellitus (DM) is a complex disease which currently affects more than 460 million people and is one of the leading cause of death worldwide. Its…”
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Targeting of tumor cells by custom antigen transfer: a novel approach for immunotherapy of cancer
Published in Frontiers in oncology (13-10-2023)“…In the early stages of carcinogenesis, the transformed cells become “invisible” to the immune system. From this moment on, the evolution of the tumor depends…”
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Therapy-Induced Stromal Senescence Promoting Aggressiveness of Prostate and Ovarian Cancer
Published in Cells (Basel, Switzerland) (01-12-2022)“…Cancer progression is supported by the cross-talk between tumor cells and the surrounding stroma. In this context, senescent cells in the tumor…”
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Reducing the Use of Frozen Section for Sentinel Node Biopsy in Breast Carcinoma: Feasibility and Outcome
Published in Anticancer research (01-05-2023)“…Sentinel lymph node biopsy (SLNB) is a standard practice for staging the axilla in breast cancer. Initially, intraoperative frozen section (FS) examination was…”
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Using gamification and IoT-based educational tools towards energy savings - some experiences from two schools in Italy and Greece
Published in Journal of ambient intelligence and humanized computing (03-01-2021)“…Climate change and the need for sustainable development have become part of our daily lives. In this context, it is crucial to involve the educational…”
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SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis
Published in Cell reports (Cambridge) (16-08-2022)“…5-Fluorouracil (5-FU) is a key component of chemotherapy for colorectal cancer (CRC). 5-FU efficacy is established by intracellular levels of folate cofactors…”
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Biomonitoring of polybrominated diphenyl ether (PBDE) pollution: A field study
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01-07-2008)“…Polybrominated diphenyl ethers (PBDEs) and cytochrome P450 enzyme activities were investigated in European eels ( Anguilla anguilla) collected from seven sites…”
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Experiences from Using Gamification and IoT-based Educational Tools in High Schools towards Energy Savings
Published 02-09-2019“…Raising awareness among young people, and especially students, on the relevance of behavior change for achieving energy savings is increasingly being…”
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