Search Results - "Nesbitt, Jarred J"
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Open-Spaced Ridged Hydrogel Scaffolds Containing TiO2-Self-Assembled Monolayer of Phosphonates Promote Regeneration and Recovery Following Spinal Cord Injury
Published in International journal of molecular sciences (16-06-2023)“…The spinal cord has a poor ability to regenerate after an injury, which may be due to cell loss, cyst formation, inflammation, and scarring. A promising…”
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Comparison of polymer scaffolds in rat spinal cord: A step toward quantitative assessment of combinatorial approaches to spinal cord repair
Published in Biomaterials (01-11-2011)“…Abstract The transected rat thoracic (T9/10 ) spinal cord model is a platform for quantitatively comparing biodegradable polymer scaffolds. Schwann cell-loaded…”
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Newly regenerated axons via scaffolds promote sub-lesional reorganization and motor recovery with epidural electrical stimulation
Published in npj Regenerative medicine (20-10-2021)“…Here, we report the effect of newly regenerated axons via scaffolds on reorganization of spinal circuitry and restoration of motor functions with epidural…”
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Early and sustained improvements in motor function in rats after infusion of allogeneic umbilical cord-derived mesenchymal stem cells following spinal cord injury
Published in Spinal cord (01-03-2021)“…Study design Animal study. Objectives Umbilical cord-derived mesenchymal stem cells (UC-MSCs) have recently been shown to hold great therapeutic potential for…”
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Neural stem cell- and Schwann cell-loaded biodegradable polymer scaffolds support axonal regeneration in the transected spinal cord
Published in Tissue engineering. Part A (01-07-2009)“…Biodegradable polymer scaffolds provide an excellent approach to quantifying critical factors necessary for restoration of function after a transection spinal…”
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A safety study on intrathecal delivery of autologous mesenchymal stromal cells in rabbits directly supporting Phase I human trials
Published in Transfusion (Philadelphia, Pa.) (01-05-2015)“…Background There are no effective treatments that slow the progression of neurodegenerative diseases. A major challenge of treatment in neurodegenerative…”
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Sustained delivery of dibutyryl cyclic adenosine monophosphate to the transected spinal cord via oligo [(polyethylene glycol) fumarate] hydrogels
Published in Tissue engineering. Part A (01-05-2011)“…This study describes the use of oligo [(polyethylene glycol) fumarate] (OPF) hydrogel scaffolds as vehicles for sustained delivery of dibutyryl cyclic…”
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Open-Spaced Ridged Hydrogel Scaffolds Containing TiO[sub.2]-Self-Assembled Monolayer of Phosphonates Promote Regeneration and Recovery Following Spinal Cord Injury
Published in International journal of molecular sciences (01-06-2023)“…The spinal cord has a poor ability to regenerate after an injury, which may be due to cell loss, cyst formation, inflammation, and scarring. A promising…”
Get full text
Journal Article -
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P13. Transduction of the rat spinal cord using adenoassociated virus serotype 2.5
Published in The spine journal (01-09-2022)“…Gene therapy is a method by which exogenous genes are introduced to treat disease or deliver drugs of interest. This is commonly done through either direct…”
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Epidural electrical stimulation assisted gait improvements in spinal cord injured rats using a combinatorial strategy with scaffolds, compounds, cells, and motor training
Published in The spine journal (01-09-2020)“…Traumatic spinal cord injury (SCI) often results in paralysis that leads to loss of quality of life for the patient and socioeconomic loss. The spinal cord has…”
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Open-Spaced Ridged Hydrogel Scaffolds Containing TiO 2 -Self-Assembled Monolayer of Phosphonates Promote Regeneration and Recovery Following Spinal Cord Injury
Published in International journal of molecular sciences (16-06-2023)“…The spinal cord has a poor ability to regenerate after an injury, which may be due to cell loss, cyst formation, inflammation, and scarring. A promising…”
Get full text
Journal Article -
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Abstract #76: Neuromodulation of the spinal cord regeneration with epidural stimulation and Schwann cell seeded hydrogel scaffolds
Published in Brain stimulation (01-03-2019)Get full text
Journal Article -
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A safety study on intrathecal delivery of autologous mesenchymal stromal cells in rabbits directly supporting P hase I human trials
Published in Transfusion (Philadelphia, Pa.) (01-05-2015)“…Background There are no effective treatments that slow the progression of neurodegenerative diseases. A major challenge of treatment in neurodegenerative…”
Get full text
Journal Article