Search Results - "Nesbitt, Jarred"

Low to moderate ethanol exposure reduces astrocyte-induced neuroinflammatory signaling and cognitive decline in presymptomatic APP/PS1 mice by Kang, Shinwoo, Lee, Jeyeon, Ali, Dina N., Choi, Sun, Nesbitt, Jarred, Min, Paul H., Trushina, Eugenia, Choi, Doo-Sup

“…Alcohol use disorder has been associated with the development of neurodegenerative diseases, including Alzheimer’s disease (AD). However, recent studies…”
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Open-Spaced Ridged Hydrogel Scaffolds Containing TiO2-Self-Assembled Monolayer of Phosphonates Promote Regeneration and Recovery Following Spinal Cord Injury by Siddiqui, Ahad M., Thiele, Frederic, Stewart, Rachel N., Rangnick, Simone, Weiss, Georgina J., Chen, Bingkun K., Silvernail, Jodi L., Strickland, Tammy, Nesbitt, Jarred J., Lim, Kelly, Schwarzbauer, Jean E., Schwartz, Jeffrey, Yaszemski, Michael J., Windebank, Anthony J., Madigan, Nicolas N.

“…The spinal cord has a poor ability to regenerate after an injury, which may be due to cell loss, cyst formation, inflammation, and scarring. A promising…”
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Partial inhibition of mitochondrial complex I ameliorates Alzheimer’s disease pathology and cognition in APP/PS1 female mice by Stojakovic, Andrea, Trushin, Sergey, Sheu, Anthony, Khalili, Layla, Chang, Su-Youne, Li, Xing, Christensen, Trace, Salisbury, Jeffrey L., Geroux, Rachel E., Gateno, Benjamin, Flannery, Padraig J., Dehankar, Mrunal, Funk, Cory C., Wilkins, Jordan, Stepanova, Anna, O’Hagan, Tara, Galkin, Alexander, Nesbitt, Jarred, Zhu, Xiujuan, Tripathi, Utkarsh, Macura, Slobodan, Tchkonia, Tamar, Pirtskhalava, Tamar, Kirkland, James L., Kudgus, Rachel A., Schoon, Renee A., Reid, Joel M., Yamazaki, Yu, Kanekiyo, Takahisa, Zhang, Song, Nemutlu, Emirhan, Dzeja, Petras, Jaspersen, Adam, Kwon, Ye In Christopher, Lee, Michael K., Trushina, Eugenia

“…Alzheimer’s Disease (AD) is a devastating neurodegenerative disorder without a cure. Here we show that mitochondrial respiratory chain complex I is an…”
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Early and sustained improvements in motor function in rats after infusion of allogeneic umbilical cord-derived mesenchymal stem cells following spinal cord injury by Moinuddin, F. M., Yolcu, Yagiz U., Wahood, Waseem, Siddiqui, Ahad M., Chen, Bingkun K., Alvi, Mohammed Ali, Goyal, Anshit, Nesbitt, Jarred J., Windebank, Anthony J., Yeh, Jiunn-chern, Petrucci, Kathy, Bydon, Mohamad

“…Study design Animal study. Objectives Umbilical cord-derived mesenchymal stem cells (UC-MSCs) have recently been shown to hold great therapeutic potential for…”
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Comparison of polymer scaffolds in rat spinal cord: A step toward quantitative assessment of combinatorial approaches to spinal cord repair by Chen, Bingkun K, Knight, Andrew M, Madigan, Nicolas N, Gross, LouAnn, Dadsetan, Mahrokh, Nesbitt, Jarred J, Rooney, Gemma E, Currier, Bradford L, Yaszemski, Michael J, Spinner, Robert J, Windebank, Anthony J

“…Abstract The transected rat thoracic (T9/10 ) spinal cord model is a platform for quantitatively comparing biodegradable polymer scaffolds. Schwann cell-loaded…”
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Neural stem cell- and Schwann cell-loaded biodegradable polymer scaffolds support axonal regeneration in the transected spinal cord by Olson, Heather E, Rooney, Gemma E, Gross, LouAnn, Nesbitt, Jarred J, Galvin, Katherine E, Knight, Andrew, Chen, BingKun, Yaszemski, Michael J, Windebank, Anthony J

“…Biodegradable polymer scaffolds provide an excellent approach to quantifying critical factors necessary for restoration of function after a transection spinal…”
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A safety study on intrathecal delivery of autologous mesenchymal stromal cells in rabbits directly supporting Phase I human trials by Chen, Bingkun K., Staff, Nathan P., Knight, Andrew M., Nesbitt, Jarred J., Butler, Greg W., Padley, Douglas J., Parisi, Joseph E., Dietz, Allan B., Windebank, Anthony J.

“…Background There are no effective treatments that slow the progression of neurodegenerative diseases. A major challenge of treatment in neurodegenerative…”
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Newly regenerated axons via scaffolds promote sub-lesional reorganization and motor recovery with epidural electrical stimulation by Siddiqui, Ahad M., Islam, Riazul, Cuellar, Carlos A., Silvernail, Jodi L., Knudsen, Bruce, Curley, Dallece E., Strickland, Tammy, Manske, Emilee, Suwan, Parita T., Latypov, Timur, Akhmetov, Nafis, Zhang, Shuya, Summer, Priska, Nesbitt, Jarred J., Chen, Bingkun K., Grahn, Peter J., Madigan, Nicolas N., Yaszemski, Michael J., Windebank, Anthony J., Lavrov, Igor A.

“…Here, we report the effect of newly regenerated axons via scaffolds on reorganization of spinal circuitry and restoration of motor functions with epidural…”
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Author Correction: Partial inhibition of mitochondrial complex I ameliorates Alzheimer’s disease pathology and cognition in APP/PS1 female mice by Stojakovic, Andrea, Trushin, Sergey, Sheu, Anthony, Khalili, Layla, Chang, Su-Youne, Li, Xing, Christensen, Trace, Salisbury, Jeffrey L., Geroux, Rachel E., Gateno, Benjamin, Flannery, Padraig J., Dehankar, Mrunal, Funk, Cory C., Wilkins, Jordan, Stepanova, Anna, O’Hagan, Tara, Galkin, Alexander, Nesbitt, Jarred, Zhu, Xiujuan, Tripathi, Utkarsh, Macura, Slobodan, Tchkonia, Tamar, Pirtskhalava, Tamar, Kirkland, James L., Kudgus, Rachel A., Schoon, Renee A., Reid, Joel M., Yamazaki, Yu, Kanekiyo, Takahisa, Zhang, Song, Nemutlu, Emirhan, Dzeja, Petras, Jaspersen, Adam, Kwon, Ye In Christopher, Lee, Michael K., Trushina, Eugenia

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Sustained delivery of dibutyryl cyclic adenosine monophosphate to the transected spinal cord via oligo [(polyethylene glycol) fumarate] hydrogels by Rooney, Gemma E, Knight, Andrew M, Madigan, Nicolas N, Gross, Louann, Chen, Bingkun, Giraldo, Catalina Vallejo, Seo, Seungmae, Nesbitt, Jarred J, Dadsetan, Mahrokh, Yaszemski, Michael J, Windebank, Anthony J

“…This study describes the use of oligo [(polyethylene glycol) fumarate] (OPF) hydrogel scaffolds as vehicles for sustained delivery of dibutyryl cyclic…”
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94. Subthreshold epidural electrical stimulation induced regeneration and motor recovery following spinal cord injury by Siddiqui, Ahad M., Ammicht, Tobias, Manske, Emilee, Chen, Bingkun, Islam, Riazul, Zhang, Shuya, Nesbitt, Jarred, Madigan, Nicolas, Lavrov, Igor, Windebank, Anthony

“…SCI is a devastating condition that leads to paralysis due to axonal damage and demyelination of the connections that control sensory and motor functions in…”
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94. Subthreshold epidural electrical stimulation induced regeneration and motor recovery following spinal cord injury by Siddiqui, Ahad M., Ammicht, Tobias, Manske, Emilee, Chen, Bingkun, Islam, Riazul, Zhang, Shuya, Nesbitt, Jarred, Madigan, Nicolas, Lavrov, Igor, Windebank, Anthony

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Open-Spaced Ridged Hydrogel Scaffolds Containing TiO[sub.2]-Self-Assembled Monolayer of Phosphonates Promote Regeneration and Recovery Following Spinal Cord Injury by Siddiqui, Ahad M, Thiele, Frederic, Stewart, Rachel N, Rangnick, Simone, Weiss, Georgina J, Chen, Bingkun K, Silvernail, Jodi L, Strickland, Tammy, Nesbitt, Jarred J, Lim, Kelly, Schwarzbauer, Jean E, Schwartz, Jeffrey, Yaszemski, Michael J, Windebank, Anthony J, Madigan, Nicolas N

“…The spinal cord has a poor ability to regenerate after an injury, which may be due to cell loss, cyst formation, inflammation, and scarring. A promising…”
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P13. Transduction of the rat spinal cord using adenoassociated virus serotype 2.5 by Siddiqui, Ahad M, Garcia, Micklaus, Sorto, Litsi Ocampo, Schwab, Stephan, la Vega, Rodolfo E. De, Chen, Bingkun, Coenen, Michael, Nesbitt, Jarred J., Zhang, Shuya, Madigan, Nicolas N., Evans, Chris, Windebank, Anthony J.

“…Gene therapy is a method by which exogenous genes are introduced to treat disease or deliver drugs of interest. This is commonly done through either direct…”
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Epidural electrical stimulation assisted gait improvements in spinal cord injured rats using a combinatorial strategy with scaffolds, compounds, cells, and motor training by Siddiqui, Ahad M., Islam, Riazul, Cuellar, Carlos, Silvernail, Jodi, Knudsen, Bruce, Curley, Dallece, Strickland, Tammy, Manske, Emilee, Latypov, Timur, Zhang, Shuya, Summer, Priska, Nesbitt, Jarred J., Chen, Bingkun, Grahn, Peter, Madigan, Nicolas N., Yaszemski, Michael J., Lavrov, Igor, Windebank, Anthony J.

“…Traumatic spinal cord injury (SCI) often results in paralysis that leads to loss of quality of life for the patient and socioeconomic loss. The spinal cord has…”
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Open-Spaced Ridged Hydrogel Scaffolds Containing TiO 2 -Self-Assembled Monolayer of Phosphonates Promote Regeneration and Recovery Following Spinal Cord Injury by Siddiqui, Ahad M, Thiele, Frederic, Stewart, Rachel N, Rangnick, Simone, Weiss, Georgina J, Chen, Bingkun K, Silvernail, Jodi L, Strickland, Tammy, Nesbitt, Jarred J, Lim, Kelly, Schwarzbauer, Jean E, Schwartz, Jeffrey, Yaszemski, Michael J, Windebank, Anthony J, Madigan, Nicolas N

“…The spinal cord has a poor ability to regenerate after an injury, which may be due to cell loss, cyst formation, inflammation, and scarring. A promising…”
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Abstract #76: Neuromodulation of the spinal cord regeneration with epidural stimulation and Schwann cell seeded hydrogel scaffolds by Cuellar, Carlos A., Siddiqui, Ahad M., Silvernail, Jodi L., Chen, Bingkun K., Knudsen, Bruce, Nesbitt, Jarred J., Grahn, Peter J., Madigan, Nicolas N., Windebank, Anthony J., Lavrov, Igor A.

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A safety study on intrathecal delivery of autologous mesenchymal stromal cells in rabbits directly supporting P hase I human trials by Chen, Bingkun K., Staff, Nathan P., Knight, Andrew M., Nesbitt, Jarred J., Butler, Greg W., Padley, Douglas J., Parisi, Joseph E., Dietz, Allan B., Windebank, Anthony J.

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