Search Results - "Nerlich, Jana"
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1
What calcium channels remember
Published in eLife (11-08-2023)“…A new mechanism involving intermediate gating states of calcium channels explains how analogue postsynaptic potentials influence neurotransmitter release…”
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2
Human antibodies neutralizing the alpha-latrotoxin of the European black widow
Published in Frontiers in immunology (12-06-2024)“…Poisoning by widow-spider (genus ) bites occurs worldwide. The illness, termed latrodectism, can cause severe and persistent pain and can lead to muscle…”
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3
Developmental Shift of Inhibitory Transmitter Content at a Central Auditory Synapse
Published in Frontiers in cellular neuroscience (19-07-2017)“…Synaptic inhibition in the CNS is mostly mediated by GABA or glycine. Generally, the use of the two transmitters is spatially segregated, but there are central…”
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4
Direct whole-cell patch-clamp recordings from small boutons in rodent primary neocortical neuron cultures
Published in STAR protocols (16-06-2023)“…Direct electrical recordings from conventional boutons in the mammalian central nervous system have proven challenging due to their small size. Here, we…”
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Engineering new-to-nature biochemical conversions by combining fermentative metabolism with respiratory modules
Published in Nature communications (07-08-2024)“…Anaerobic microbial fermentations provide high product yields and are a cornerstone of industrial bio-based processes. However, the need for redox balancing…”
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6
Fully-primed slowly-recovering vesicles mediate presynaptic LTP at neocortical neurons
Published in Proceedings of the National Academy of Sciences - PNAS (24-10-2023)“…Pre- and postsynaptic forms of long-term potentiation (LTP) are candidate synaptic mechanisms underlying learning and memory. At layer 5 pyramidal neurons, LTP…”
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Human iPSC-Derived Neurons with Reliable Synapses and Large Presynaptic Action Potentials
Published in The Journal of neuroscience (12-06-2024)“…Understanding the function of the human brain requires determining basic properties of synaptic transmission in human neurons. One of the most fundamental…”
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8
NMDA-receptor-Fc-fusion constructs neutralize anti-NMDA receptor antibodies
Published in Brain (London, England : 1878) (02-05-2023)“…Abstract N-methyl-D-aspartate receptor (NMDAR) encephalitis is the most common subtype of autoimmune encephalitis characterized by a complex neuropsychiatric…”
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9
Dynamic fidelity control to the central auditory system: synergistic glycine/GABAergic inhibition in the cochlear nucleus
Published in The Journal of neuroscience (27-08-2014)“…GABA and glycine are the major inhibitory transmitters that attune neuronal activity in the CNS of mammals. The respective transmitters are mostly spatially…”
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10
Regulation of P2X7 receptor function of neural progenitor cells in the hippocampal subgranular zone by neuronal activity in the dentate gyrus
Published in Neuropharmacology (15-09-2018)“…P2X7 receptors (Rs) mediate apoptosis/necrosis in neuronal and non-neuronal systems. Patch-clamp recordings from dentate gyrus (DG) granule cells in acutely…”
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11
Tonotopic action potential tuning of maturing auditory neurons through endogenous ATP
Published in The Journal of physiology (15-02-2017)“…Key points Following the genetically controlled formation of neuronal circuits, early firing activity guides the development of sensory maps in the auditory,…”
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12
The lipid dependence of diadinoxanthin de-epoxidation presents new evidence for a macrodomain organization of the diatom thylakoid membrane
Published in Journal of plant physiology (15-11-2009)“…The present study shows that thylakoid membranes of the diatom Cyclotella meneghiniana contain much higher amounts of negatively charged lipids than higher…”
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13
Inhibitory properties underlying non-monotonic input-output relationship in low-frequency spherical bushy neurons of the gerbil
Published in Frontiers in neural circuits (31-03-2015)“…Spherical bushy cells (SBCs) of the anteroventral cochlear nucleus (AVCN) receive input from large excitatory auditory nerve (AN) terminals, the endbulbs of…”
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14
Purinergic modulation of neuronal activity in developing auditory brainstem
Published in The Journal of neuroscience (01-08-2012)“…In the developing nervous system, spontaneous neuronal activity arises independently of experience or any environmental input. This activity may play a major…”
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15
Activity-dependent modulation of inhibitory synaptic kinetics in the cochlear nucleus
Published in Frontiers in neural circuits (23-12-2014)“…Spherical bushy cells (SBCs) in the anteroventral cochlear nucleus respond to acoustic stimulation with discharges that precisely encode the phase of…”
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