Search Results - "Nera, E"

Calorie restriction and cellular proliferation in various tissues of the female Swiss Webster mouse by Lok, E, Scott, F W, Mongeau, R, Nera, E A, Malcolm, S, Clayson, D B

“…Two experiments have been conducted to determine the effects of calorie restriction on cellular proliferation in female mouse tissues. In the first experiment,…”
Get more information

Toxicological consequences of aroclor 1254 ingestion by female rhesus (Macaca mulatta) monkeys and their nursing infants. Part 3: Post-reproduction and pathological findings by Arnold, D.L., Nera, E.A., Stapley, R., Bryce, F., Fernie, S., Tolnai, G., Miller, D., Hayward, S., Campbell, J.S., Greer, I.

“…A group of 80 menstruating rhesus (Macaca mulatta) monkeys were randomly allocated to four similar rooms (20 monkeys/room) and then to one of five dose groups…”
Get full text

Domoic acid poisoning and mussel-associated intoxication: preliminary investigations into the response of mice and rats to toxic mussel extract by Iverson, F, Truelove, J, Nera, E, Tryphonas, L, Campbell, J, Lok, E

“…Consumption of cultivated blue mussels from Prince Edward Island was recently associated with episodes of gastro-intestinal and neurological distress. Extracts…”
Get more information

Dietary restriction, cell proliferation and carcinogenesis: a preliminary study by Lok, E, Nera, E A, Iverson, F, Scott, F, So, Y, Clayson, D B

“…Four groups of female Swiss Webster mice were given either laboratory chow or a purified (semi-synthetic) diet (AIN-76A) either ad libitum or at 75% of the ad…”
Get more information

A carcinogenesis reversibility study of the effects of butylated hydroxyanisole on the forestomach and urinary bladder in male Fischer 344 rats by Nera, E A, Iverson, F, Lok, E, Armstrong, C L, Karpinski, K, Clayson, D B

“…A reversibility study was initiated to determine if the length of feeding with 2% butylated hydroxyanisole (BHA) altered the incidence of forestomach lesions…”
Get more information

Acute neurotoxicity of domoic acid in the rat by Tryphonas, L, Truelove, J, Nera, E, Iverson, F

“…A recent outbreak of human food poisoning, characterized by severe gastrointestinal and neurologic abnormalities, with a fatal outcome in 3 patients, was…”
Get more information

The significance of induced forestomach tumors by Clayson, D B, Iverson, F, Nera, E A, Lok, E

“…This report addresses the development of cancerous lesions in the rodent forestomach, the nature of the chemicals that induce these lesions and their…”
Get full text

Experimental oral toxicity of domoic acid in cynomolgus monkeys (Macaca fascicularis) and rats. Preliminary investigations by Tryphonas, L, Truelove, J, Todd, E, Nera, E, Iverson, F

“…A recent outbreak of marine food poisoning in humans was attributed to the consumption of blue mussels (Mytilus edulis L.) contaminated with domoic acid (DA)…”
Get more information

The effect of butylated hydroxytoluene on the growth of enzyme-altered foci in male Fischer 344 rat liver tissue by Lok, E, Mehta, R, Jee, P, Laver, G, Nera, E A, McMullen, E, Clayson, D B

“…Butylated hydroxytoluene (BHT) is a synthetic, food-use, phenolic antioxidant. It has previously been demonstrated to be operationally non-genotoxic and, in…”
Get more information

Effect of addition of dried healthy or diseased parsnip root tissue to a modified AIN-76A diet on cell proliferation and histopathology in the liver, oesophagus and forestomach of male Swiss Webster mice by Mongeau, R, Brassard, R, Cerkauskas, R, Chiba, M, Lok, E, Nera, E A, Jee, P, McMullen, E, Clayson, D B

“…Umbelliferous crop plants, including the parsnip (Pastinaca sativa L.), elaborate enhanced levels of furocoumarins, including psoralens, when subjected to…”
Get more information

The effect of different levels of dietary α-linolenic and other fatty acids on mammary gland ductular cell proliferation in female Swiss Webster mice by Lok, E., Jee, P., Ratnayake, W.M.N., Scott, F.W., Nera, E.A., Fernie, S., McMullen, E., Clayson, D.B.

“…In previous work we have shown that changing the fatty acid composition of a constant amount of fat in a modified AIN-76A diet affected the level of ductular…”
Get full text

The potential for the use of cell proliferation studies in carcinogen risk assessment by Clayson, D B, Nera, E A, Lok, E

“…The use of observations on cellular proliferation in assessing the mechanism of action of certain factors in the genesis of tumors of the urinary bladder,…”
Get more information

Effects of deoxynivalenol (vomitoxin) on the humoral and cellular immunity of mice by Tryphonas, H, Iverson, F, So, Y, Nera, E A, McGuire, P F, O'Grady, L, Clayson, D B, Scott, P M

“…Sublethal doses (0.00, 0.25, 0.50 and 1.00 mg/kg b.w./day) of vomitoxin (deoxynivalenol; DON) were studied for their effects on humoral and cellular immunity…”
Get more information

Short-term effects of butylated hydroxytoluene on the Wistar rat liver, urinary bladder and thyroid gland by Briggs, D, Lok, E, Nera, E A, Karpinski, K, Clayson, D B

“…Long-term feeding of butylated hydroxytoluene (BHT) to rats and mice has been linked to the enhancement of the incidence of liver tumors. It is shown in this…”
Get more information

The toxicity of orally administered deoxynivalenol (vomitoxin) in rats and mice by Arnold, D L, McGuire, P F, Nera, E A, Karpinski, K F, Bickis, M G, Zawidzka, Z Z, Fernie, S, Vesonder, R F

“…Two studies were conducted with weanling male rodents in an attempt to ascertain more precisely the toxic effects of deoxynivalenol (DON). In a feeding study…”
Get more information

Histopathological and radioautographical studies on the forestomach of F344 rats treated with butylated hydroxyanisole and related chemicals by Clayson, D B, Iverson, F, Nera, E, Lok, E, Rogers, C, Rodrigues, C, Page, D, Karpinski, K

“…Butylated hydroxyanisole, when fed to male Fischer 344 rats for periods of 9 days or more, led to forestomach epithelial cell necrosis and regeneration. Both…”
Get more information

Short-term pathological and proliferative effects of butylated hydroxyanisole and other phenolic antioxidants in the forestomach of Fischer 344 rats by Nera, E A, Lok, E, Iverson, F, Ormsby, E, Karpinski, K F, Clayson, D B

“…Food grade butylated hydroxyanisole (BHA) when incorporated in the diet and fed to male Fischer 344 rats for 9 or 27 days induced proliferative squamous…”
Get more information

Effect of varying the type of fat in a semi-purified AIN-76A diet on cellular proliferation in the mammary gland and intestinal crypts in female Swiss Webster mice by Lok, E, Ratnayake, W M, Scott, F W, Mongeau, R, Fernie, S, Nera, E A, Malcolm, S, McMullen, E, Jee, P, Clayson, D B

“…Young virgin female Swiss Webster mice were fed AIN-76A semi-purified diets containing equal weights of different fats for approximately 30 days. Using…”
Get more information

The importance of cellular proliferation induced by BHA and BHT by Clayson, D B, Iverson, F, Nera, E A, Lok, E

Get more information

Short-term effects of various phenols and acids on the Fischer 344 male rat forestomach epithelium by Rodrigues, C, Lok, E, Nera, E, Iverson, F, Page, D, Karpinski, K, Clayson, D B

“…A series of phenols and acids was fed to rats for 9 days to determine effects on the [methyl-3H]thymidine labelling index and the histological appearance of…”
Get more information