Search Results - "Neo, Suat Peng"

Systematic Identification of Factors for Provirus Silencing in Embryonic Stem Cells by Yang, Bin Xia, EL Farran, Chadi A., Guo, Hong Chao, Yu, Tao, Fang, Hai Tong, Wang, Hao Fei, Schlesinger, Sharon, Seah, Yu Fen Samantha, Goh, Germaine Yen Lin, Neo, Suat Peng, Li, Yinghui, Lorincz, Matthew C., Tergaonkar, Vinay, Lim, Tit-Meng, Chen, Lingyi, Gunaratne, Jayantha, Collins, James J., Goff, Stephen P., Daley, George Q., Li, Hu, Bard, Frederic A., Loh, Yuin-Han

“…Embryonic stem cells (ESCs) repress the expression of exogenous proviruses and endogenous retroviruses (ERVs). Here, we systematically dissected the cellular…”
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Scd5p mediates phosphoregulation of actin and endocytosis by the type 1 phosphatase Glc7p in yeast by Zeng, Guisheng, Huang, Bo, Neo, Suat Peng, Wang, Junxia, Cai, Mingjie

“…Pan1p plays essential roles in both actin and endocytosis in yeast. It interacts with, and regulates the function of, multiple endocytic proteins and actin…”
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Loss of ABCA8B decreases myelination by reducing oligodendrocyte precursor cells in mice by Liu, Yiran, Castano, David, Girolamo, Francesco, Trigueros-Motos, Laia, Bae, Han-Gyu, Neo, Suat Peng, Oh, Jeongah, Narayanaswamy, Pradeep, Torta, Federico, Rye, Kerry Anne, Jo, Dong-Gyu, Gunaratne, Jayantha, Jung, Sangyong, Virgintino, Daniela, Singaraja, Roshni R.

“…The myelin sheath, which is wrapped around axons, is a lipid-enriched structure produced by mature oligodendrocytes. Disruption of the myelin sheath is…”
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Comprehensive Interactome Analysis for the Sole Adenylyl Cyclase Cyr1 of Candida albicans by Zeng, Guisheng, Neo, Suat Peng, Pang, Li Mei, Gao, Jiaxin, Chong, Shu Chen, Gunaratne, Jayantha, Wang, Yue

“…Cyr1, the sole adenylyl cyclase of the fungal pathogen Candida albicans, is a central component of the cAMP/protein kinase A signaling pathway that controls…”
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System-wide vitreous proteome dissection reveals impaired sheddase activity in diabetic retinopathy by Alli-Shaik, Asfa, Qiu, Beiying, Lai, Siew Li, Cheung, Ning, Tan, Gavin, Neo, Suat Peng, Tan, Alison, Cheung, Chiu Ming Gemmy, Hong, Wanjin, Wong, Tien Yin, Wang, Xiaomeng, Gunaratne, Jayantha

“…Rationale: Diabetic retinopathy (DR) is a major complication of diabetes mellitus causing significant vision loss. DR is a multifactorial disease involving…”
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Novel Septin-Associated Protein, Syp1p, Is Required for Normal Cell Cycle-Dependent Septin Cytoskeleton Dynamics in Yeast by Qiu, Wenjie, Neo, Suat Peng, Yu, Xianwen, Cai, Mingjie

“…Septins are a family of GTP-binding proteins whose heterooligomeric complex is the basic structural element of the septin filaments found in many eukaryotic…”
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EPLIN-β is a novel substrate of ornithine decarboxylase antizyme 1 and mediates cellular migration by Li, Dan, Neo, Suat Peng, Gunaratne, Jayantha, Sabapathy, Kanaga

“…Polyamines promote cellular proliferation. Their levels are controlled by ornithine decarboxylase antizyme 1 (Az1, encoded by OAZ1), through the…”
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Englerin A Rewires Phosphosignaling via Hsp27 Hyperphosphorylation to Induce Cytotoxicity in Renal Cancer Cells by Neo, Suat Peng, Alli-Shaik, Asfa, Wee, Sheena, Lim, Zijie, Gunaratne, Jayantha

“…Englerin A (EA) is a small-molecule natural product with selective cytotoxicity against renal cancer cells. EA has been shown to induce apoptosis and cell…”
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Tensin3 interaction with talin drives the formation of fibronectin-associated fibrillar adhesions by Atherton, Paul, Konstantinou, Rafaella, Neo, Suat Peng, Wang, Emily, Balloi, Eleonora, Ptushkina, Marina, Bennett, Hayley, Clark, Kath, Gunaratne, Jayantha, Critchley, David, Barsukov, Igor, Manser, Edward, Ballestrem, Christoph

“…The formation of healthy tissue involves continuous remodeling of the extracellular matrix (ECM). Whilst it is known that this requires integrin-associated…”
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Single-nucleotide-resolution sequencing of human N 6-methyldeoxyadenosine reveals strand-asymmetric clusters associated with SSBP1 on the mitochondrial genome by Koh, Casslynn W Q, Goh, Yeek Teck, Toh, Joel D W, Neo, Suat Peng, Ng, Sarah B, Gunaratne, Jayantha, Gao, Yong-Gui, Quake, Stephen R, Burkholder, William F, Goh, Wee Siong S

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Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cells by Pfister, Neil T, Fomin, Vitalay, Regunath, Kausik, Zhou, Jeffrey Y, Zhou, Wen, Silwal-Pandit, Laxmi, Freed-Pastor, William A, Laptenko, Oleg, Neo, Suat Peng, Bargonetti, Jill, Hoque, Mainul, Tian, Bin, Gunaratne, Jayantha, Engebraaten, Olav, Manley, James L, Børresen-Dale, Anne-Lise, Neilsen, Paul M, Prives, Carol

“…Mutant p53 impacts the expression of numerous genes at the level of transcription to mediate oncogenesis. We identified vascular endothelial growth factor…”
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Identification and characterization of host proteins bound to dengue virus 3' UTR reveal an antiviral role for quaking proteins by Liao, Kuo-Chieh, Chuo, Vanessa, Ng, Wy Ching, Neo, Suat Peng, Pompon, Julien, Gunaratne, Jayantha, Ooi, Eng Eong, Garcia-Blanco, Mariano A

“…The four dengue viruses (DENV1-4) are rapidly reemerging infectious RNA viruses. These positive-strand viral genomes contain structured 3' untranslated regions…”
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Feedback regulation on PTEN/AKT pathway by the ER stress kinase PERK mediated by interaction with the Vault complex by Zhang, Wei, Neo, Suat Peng, Gunaratne, Jayantha, Poulsen, Anders, Boping, Liu, Ong, Esther Hongqian, Sangthongpitag, Kanda, Pendharkar, Vishal, Hill, Jeffrey, Cohen, Stephen M.

“…The high proliferation rate of cancer cells, together with environmental factors such as hypoxia and nutrient deprivation can cause Endoplasmic Reticulum (ER)…”
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HOXC10 suppresses browning to maintain white adipocyte identity by H Y Angeline, Tan, M F Michelle, Sim, Tan, Shi-Xiong, Ng, Yvonne, Gan, Sin Yee, Li, Hongyu, Neo, Suat Peng, Gunaratne, Jayantha, Xu, Feng, Han, Weiping

“…Promoting beige adipocyte development within white adipose tissue (WAT) is a potential therapeutic approach to staunch the current obesity epidemic…”
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Regulation of the Yeast Formin Bni1p by the Actin-Regulating Kinase Prk1p by Wang, Junxia, Neo, Suat Peng, Cai, Mingjie

“…The formin family of proteins promotes the assembly of linear actin filaments in the cells of diverse eukaryotic organisms. The predominant formins in…”
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Mutant p53 interactome identifies nardilysin as a p53R273H-specific binding partner that promotes invasion by Coffill, Cynthia R, Muller, Patricia A J, Oh, Hue Kian, Neo, Suat Peng, Hogue, Kelly A, Cheok, Chit Fang, Vousden, Karen H, Lane, David P, Blackstock, Walter P, Gunaratne, Jayantha

“…The invasiveness of tumour cells depends on changes in cell shape, polarity and migration. Mutant p53 induces enhanced tumour metastasis in mice, and human…”
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Single-nucleotide-resolution sequencing of human N6-methyldeoxyadenosine reveals strand-asymmetric clusters associated with SSBP1 on the mitochondrial genome by Koh, Casslynn W Q, Goh, Yeek Teck, Toh, Joel D W, Neo, Suat Peng, Ng, Sarah B, Gunaratne, Jayantha, Gao, Yong-Gui, Quake, Stephen R, Burkholder, William F, Goh, Wee Siong S

“…Abstract N 6-methyldeoxyadenosine (6mA) is a well-characterized DNA modification in prokaryotes but reports on its presence and function in mammals have been…”
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Extensive mass spectrometry-based analysis of the fission yeast proteome: the Schizosaccharomyces pombe PeptideAtlas by Gunaratne, Jayantha, Schmidt, Alexander, Quandt, Andreas, Neo, Suat Peng, Saraç, Omer Sinan, Gracia, Tannia, Loguercio, Salvatore, Ahrné, Erik, Xia, Rachel Li Hai, Tan, Keng Hwa, Lössner, Christopher, Bähler, Jürg, Beyer, Andreas, Blackstock, Walter, Aebersold, Ruedi

“…We report a high quality and system-wide proteome catalogue covering 71% (3,542 proteins) of the predicted genes of fission yeast, Schizosaccharomyces pombe,…”
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Extensive Mass Spectrometry-based Analysis of the Fission Yeast Proteome by Gunaratne, Jayantha, Schmidt, Alexander, Quandt, Andreas, Neo, Suat Peng, Saraç, Ömer Sinan, Gracia, Tannia, Loguercio, Salvatore, Ahrné, Erik, Xia, Rachel Li Hai, Tan, Keng Hwa, Lössner, Christopher, Bähler, Jürg, Beyer, Andreas, Blackstock, Walter, Aebersold, Ruedi

“…We report a high quality and system-wide proteome catalogue covering 71% (3,542 proteins) of the predicted genes of fission yeast, Schizosaccharomyces pombe,…”
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