Search Results - "Nemesh, J"

Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities by Madison, J M, Zhou, F, Nigam, A, Hussain, A, Barker, D D, Nehme, R, van der Ven, K, Hsu, J, Wolf, P, Fleishman, M, O'Dushlaine, C, Rose, S, Chambert, K, Lau, F H, Ahfeldt, T, Rueckert, E H, Sheridan, S D, Fass, D M, Nemesh, J, Mullen, T E, Daheron, L, McCarroll, S, Sklar, P, Perlis, R H, Haggarty, S J

“…Bipolar disorder (BD) is a common neuropsychiatric disorder characterized by chronic recurrent episodes of depression and mania. Despite evidence for high…”
Get full text

Early-Onset Psychosis and Gray and White Matter Volume Abnormalities

Get full text

Conserved noncoding sequences are selectively constrained and not mutation cold spots by Dermitzakis, Emmanouil T, Hirschhorn, Joel N, Drake, Jared A, Bird, Christine, Nemesh, James, Thomas, Daryl J, Newton-Cheh, Christopher, Reymond, Alexandre, Excoffier, Laurent, Attar, Homa, Antonarakis, Stylianos E

“…Noncoding genetic variants are likely to influence human biology and disease, but recognizing functional noncoding variants is difficult. Approximately 3% of…”
Get full text

The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes by Brewer, Carl, Daly, Mark, Bolk, Stacey, Gaudet, Daniel, Groop, Leif, Nemesh, James, Vohl, Marie-Claude, Schaffner, Stephen F, Hudson, Thomas J, Altshuler, David, Lindgren, Cecilia M, Lander, Eric S, Klannemark, Mia, Hirschhorn, Joel N, Lane, Charles R, Tuomi, Tiinamaija

“…Genetic association studies are viewed as problematic and plagued by irreproducibility. Many associations have been reported for type 2 diabetes, but none have…”
Get full text

Characterization of single-nucleotide polymorphisms in coding regions of human genes by Lander, Eric S, Cargill, Michele, Altshuler, David, Ireland, James, Sklar, Pamela, Ardlie, Kristin, Patil, Nila, Lane, Charles R, Lim, Esther P, Kalyanaraman, Nilesh, Nemesh, James, Ziaugra, Liuda, Friedland, Lisa, Rolfe, Alex, Warrington, Janet, Lipshutz, Robert, Daley, George Q

“…A major goal in human genetics is to understand the role of common genetic variants in susceptibility to common diseases. This will require characterizing the…”
Get full text

Characterization of single-nucleotide polymorphisms in coding regions of human genes by Cargill, Michele

Get full text

The common PPAR gamma Pro12Ala polymorphism is associated with increased risk of type 2 diabetes by Altshuler, D, Hirschhorn, J N, Klannemark, M, Lindgren, C M, Vohl, M-C, Nemesh, J, Lane, C R, Schaffner, S F, Bolk, S, Brewer, C, Tuomi, T, Gaudet, D, Hudson, T J, Daly, M

“…Genetic association studies are viewed as problematic and plagued by irreproducibility. Many associations have been reported for type 2 diabetes, but none have…”
Get full text

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes by Altshuler, D, Hirschhorn, J N, Klannemark, M, Lindgren, C M, Vohl, M C, Nemesh, J, Lane, C R, Schaffner, S F, Bolk, S, Brewer, C, Tuomi, T, Gaudet, D, Hudson, T J, Daly, M, Groop, L, Lander, E S

“…Genetic association studies are viewed as problematic and plagued by irreproducibility. Many associations have been reported for type 2 diabetes, but none have…”
Get full text