Search Results - "Nemecz, Miruna"

The Distinct Effects of Palmitic and Oleic Acid on Pancreatic Beta Cell Function: The Elucidation of Associated Mechanisms and Effector Molecules by Nemecz, Miruna, Constantin, Alina, Dumitrescu, Madalina, Alexandru, Nicoleta, Filippi, Alexandru, Tanko, Gabriela, Georgescu, Adriana

“…In this study, we aimed to identify the mechanisms underlying the different effects of palmitic acid and oleic acid on human pancreatic beta cell function. To…”
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Extracellular Vesicles from Adipose Tissue Stem Cells in Diabetes and Associated Cardiovascular Disease; Pathobiological Impact and Therapeutic Potential by Constantin, Alina, Filippi, Alexandru, Alexandru, Nicoleta, Nemecz, Miruna, Georgescu, Adriana

“…Adipose tissue-derived stem cells (ADSCs) are pluripotent mesenchymal stem cells found in relatively high percentages in the adipose tissue and able to…”
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Microvesicle-associated and circulating microRNAs in diabetic dyslipidemia: miR-218, miR-132, miR-143, and miR-21, miR-122, miR-155 have biomarker potential by Nemecz, Miruna, Stefan, Diana Simona, Comarița, Ioana Karla, Constantin, Alina, Tanko, Gabriela, Guja, Cristian, Georgescu, Adriana

“…Abstract Background Circulating MicroRNAs (miRNAs) carried by microvesicles (MVs) have various physiological and pathological functions by post-transcriptional…”
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Microvesicles and Microvesicle-Associated microRNAs Reflect Glioblastoma Regression: Microvesicle-Associated miR-625-5p Has Biomarker Potential by Simionescu, Natalia, Nemecz, Miruna, Petrovici, Anca-Roxana, Nechifor, Ioan Sebastian, Buga, Razvan-Cristian, Dabija, Marius Gabriel, Eva, Lucian, Georgescu, Adriana

“…Glioblastoma (GB) is the most aggressive and recurrent form of brain cancer in adults. We hypothesized that the identification of biomarkers such as certain…”
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Stem cell‐derived extracellular vesicles reduce the expression of molecules involved in cardiac hypertrophy—In a model of human-induced pluripotent stem cell-derived cardiomyocytes by Constantin, Alina, Comarița, Ioana Karla, Alexandru, Nicoleta, Filippi, Alexandru, Bojin, Florina, Gherghiceanu, Mihaela, Vîlcu, Alexandra, Nemecz, Miruna, Niculescu, Loredan Stefan, Păunescu, Virgil, Georgescu, Adriana

“…Cardiac pathological hypertrophy is the major risk factor that usually progresses to heart failure. We hypothesized that extracellular vesicles (EVs), known to…”
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Hypertension Associated With Hyperlipidemia Induced Different MicroRNA Expression Profiles in Plasma, Platelets, and Platelet-Derived Microvesicles; Effects of Endothelial Progenitor Cell Therapy by Alexandru, Nicoleta, Constantin, Alina, Nemecz, Miruna, Comariţa, Ioana Karla, Vîlcu, Alexandra, Procopciuc, Anastasia, Tanko, Gabriela, Georgescu, Adriana

“…The aim of this study was to analyze the expressed profiles of miRNAs in plasma, platelets, and platelet-derived microvesicles (PMVs) obtained from…”
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Natural Polymer-Cell Bioconstructs for Bone Tissue Engineering by Titorencu, Irina, Albu, Madalina Georgiana, Nemecz, Miruna, Jinga, Victor V

“…The major goal of bone tissue engineering is to develop bioconstructs which substitute the functionality of damaged natural bone structures as much as possible…”
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Platelets of Healthy Origins Promote Functional Improvement of Atherosclerotic Endothelial Progenitor Cells by Alexandru, Nicoleta, Safciuc, Florentina, Constantin, Alina, Nemecz, Miruna, Tanko, Gabriela, Filippi, Alexandru, Dragan, Emanuel, Bãdilã, Elisabeta, Georgescu, Adriana

“…The purpose was to evaluate the effect of platelets on functional properties of late endothelial progenitor cells (EPCs), in the direct co-culture conditions,…”
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Therapeutic Potential of Stem Cell-Derived Extracellular Vesicles on Atherosclerosis-Induced Vascular Dysfunction and Its Key Molecular Players by Comariţa, Ioana Karla, Vîlcu, Alexandra, Constantin, Alina, Procopciuc, Anastasia, Safciuc, Florentina, Alexandru, Nicoleta, Dragan, Emanuel, Nemecz, Miruna, Filippi, Alexandru, Chiţoiu, Leona, Gherghiceanu, Mihaela, Georgescu, Adriana

“…Atherosclerosis is a progressive, chronic inflammatory disease of the large arteries caused by the constant accumulation of cholesterol, followed by…”
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Role of MicroRNA in Endothelial Dysfunction and Hypertension by Nemecz, Miruna, Alexandru, Nicoleta, Tanko, Gabriela, Georgescu, Adriana

“…Purpose of Review Hypertension is either a cause or a consequence of the endothelial dysfunction and a major risk factor for cardiovascular disease (CVD). In…”
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Irbesartan administration therapeutically influences circulating endothelial progenitor cell and microparticle mobilization by involvement of pro-inflammatory cytokines by Georgescu, Adriana, Alexandru, Nicoleta, Nemecz, Miruna, Titorencu, Irina, Popov, Doina

“…Circulating microparticles (MPs) and endothelial progenitor cells (EPCs) correlate with endothelial dysfunction and contribute to the pathogenesis of…”
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Sera of Obese Type 2 Diabetic Patients Undergoing Metabolic Surgery Instead of Conventional Treatment Exert Beneficial Effects on Beta Cell Survival and Function: Results of a Randomized Clinical Study by Constantin, Alina, Dumitrescu, Mădălina, Nemecz, Miruna, Picu, Ariana, Smeu, Bogdan, Guja, Cristian, Alexandru, Nicoleta, Georgescu, Adriana, Tanko, Gabriela

“…Background Pancreatic beta cells are highly sensitive to oxidative and endoplasmic reticulum (ER) stress, commonly occurring in type 2 diabetes (T2D) and…”
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Dysfunction of human subcutaneous fat arterioles in obesity alone or obesity associated with Type 2 diabetes by Georgescu, Adriana, Popov, Doina, Constantin, Anamaria, Nemecz, Miruna, Alexandru, Nicoleta, Cochior, Daniel, Tudor, Aura

“…The aim of the present study was to examine the effects of obesity alone and obesity associated with Type 2 diabetes on the structure, vascular reactivity and…”
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Long-term high glucose concentration influences Akt, ERK1/2, and PTP1B protein expression in human aortic smooth muscle cells by Popov, Doina, Nemecz, Miruna, Dumitrescu, Madalina, Georgescu, Adriana, Böhmer, Frank D.

“…Hyperglycemia stimulates a plethora of intracellular signaling pathways within the cells of the vascular wall resulting in dysfunction-associated pathologies…”
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Enoxaparin reduces adrenergic contraction of resistance arterioles in aging and in aging associated with diabetes via engagement of MAP kinase pathway by Georgescu, Adriana, Alexandru, Nicoleta, Nemecz, Miruna, Titorencu, Irina, Popov, Doina

“…The arterial endothelial dysfunction in aging and diabetes remains a clinical problem. We questioned the effect of the low-molecular-weight heparin,…”
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MicroRNA-containing microvesicles of healthy origins: a potential tool for the therapy of atherosclerosis by Georgescu, Adriana, Alexandru, Nicoleta, Safciuc, Florentina, Constantin, Alina, Nemecz, Miruna, Tanko, Gabriela, Filippi, Alexandru, Dragan, Emanuel, Simionescu, Maya

“…Background: Microvesicles, endothelial progenitor cells (EPC) and circulating microRNAs (miRNAs) are considered as regulators in atherosclerosis but their…”
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Hypertension induces compensatory left ventricular hypertrophy by a mechanism involving gap junction lateralization and overexpression of CD36, PKC and MMP-2 by Dumitrescu, Mădălina, Constantin, Alina, Nemecz, Andreea Miruna, Drăgan, Emanuel, Popov, Lucia Doina, Tanko, Gabriela

“…Hypertension-induced left ventricular hypertrophy evolves initially as an adaptive response meant to minimize ventricular wall stress. The mechanisms involved…”
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