Search Results - "Nemec, Paige S."

Dog leukocyte antigen‐88034:01 presents nonamer peptides from canine distemper virus hemagglutinin, large polymerase, and matrix proteins by Nemec, Paige S., Holmes, Jennifer C., Hess, Paul R.

“…Canine spontaneous cancers may offer greater fidelity than rodent models in advancing clinical immunotherapies. Boxers in particular are distinguished as study…”
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The prevalent Boxer MHC class Ia allotype dog leukocyte antigen (DLA)‐88034:01 preferentially binds nonamer peptides with a defined motif by Nemec, Paige S., Kapatos, Alexander, Holmes, Jennifer C., Hess, Paul R.

“…Development of effective immunotherapy for chemoresistant malignancies can be advanced by studies in spontaneous cancer models, such as the dog. A crucial…”
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The canine MHC class Ia allele DLA-88508:01 presents diverse self- and canine distemper virus-origin peptides of varying length that have a conserved binding motif by Ross, Peter, Nemec, Paige S., Kapatos, Alexander, Miller, Keith R., Holmes, Jennifer C., Suter, Steven E., Buntzman, Adam S., Soderblom, Erik J., Collins, Edward J., Hess, Paul R.

“…•DLA-88*508:01 binds peptides 9–12 amino acids in length, preferring 9- and 11-mers.•Hydrophobic residues at positions 2, 3, and K, R or F at the C-terminus…”
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Cancer‐testis antigens in canine histiocytic sarcoma and other malignancies by Nemec, Paige S., Kapatos, Alexander, Holmes, Jennifer C., Stowe, Devorah M., Hess, Paul R.

“…Cancer‐testis antigens (CTAs) are a category of self proteins aberrantly expressed in diverse malignancies, mostly solid tumours, due to epigenetic…”
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The prevalent Boxer MHC class Ia allele Dog Leukocyte Antigen (DLA)-88034:01 presents 9-mer peptides with a defined binding motif by Hess, Paul R., Nemec, Paige S., Kapatos, Alexander, Holmes, Jennifer C.

“…Adoptive cell transfer (ACT) for chemoresistant malignancies can induce dramatic remissions and prolong life, but factors that determine T-cell efficacy and…”
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